Detailed information NTG0713628

Bioinformatically predicted

Overview

• Name: comA/nlmT
• Type: Regulator
• Locus tag: NPS16_RS01315
• Genome accession: NZ_CP101986
• Coordinates: 281843..284125 (+)
• Length: 760 a.a.
• NCBI ID: WP_002271629.1
• Uniprot ID: -
• Organism: Streptococcus mutans strain COCC33-14
• Function: transport of ComC (predicted from homology) Competence regulation

Genomic Context

Location: 276843..289125

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
NPS16_RS01275 (NPS16_01275)	-	277613..277888 (+)	276	WP_002278146.1	hypothetical protein	-
NPS16_RS01280 (NPS16_01280)	-	277885..278061 (+)	177	WP_014834812.1	hypothetical protein	-
NPS16_RS01285 (NPS16_01285)	-	278102..278263 (+)	162	WP_162137516.1	hypothetical protein	-
NPS16_RS01290 (NPS16_01290)	-	278737..278946 (+)	210	WP_002264457.1	hypothetical protein	-
NPS16_RS01295 (NPS16_01295)	-	279183..279440 (+)	258	WP_025998437.1	hypothetical protein	-
NPS16_RS01300 (NPS16_01300)	-	280541..280759 (+)	219	WP_019319873.1	Blp family class II bacteriocin	-
NPS16_RS01305 (NPS16_01305)	-	280784..281188 (+)	405	WP_226730863.1	hypothetical protein	-
NPS16_RS01310 (NPS16_01310)	-	281238..281414 (+)	177	WP_002284943.1	hypothetical protein	-
NPS16_RS01315 (NPS16_01315)	comA/nlmT	281843..284125 (+)	2283	WP_002271629.1	peptide cleavage/export ABC transporter	Regulator
NPS16_RS01320 (NPS16_01320)	comB/nlmE	284139..285041 (+)	903	WP_002266018.1	HlyD family efflux transporter periplasmic adaptor subunit	Regulator
NPS16_RS01325 (NPS16_01325)	-	285417..287084 (+)	1668	WP_002271628.1	transcription antiterminator	-
NPS16_RS01330 (NPS16_01330)	ulaG	287664..288755 (+)	1092	WP_002263526.1	L-ascorbate 6-phosphate lactonase	-

Sequence

Protein

• Length: 760 a.a.
• Molecular weight: 85108.80 Da
• Isoelectric Point: 8.9003

>NTDB_id=713628 NPS16_RS01315 WP_002271629.1 281843..284125(+) (comA/nlmT) [Streptococcus mutans strain COCC33-14]
MKQVIYVVLIVIAVNILLEVIKRVTKRGGTVSSSNPLPDGQSKLFWRRHYKLVPQIDTRDCGPAVLASVAKHYGSNYSIA
YLRELSKTNKQGTTALGIVEAAKKLGFETRSIKADMTLFDYNDLTYPFIVHVIKGKRLQHYYVVYGSQNNQLIIGDPDPS
VKVTRMSKERFQSEWTGLAIFLAPQPNYKPHKGEKNGLSNFFPLIFKQKALMTYIIIASLIVTLIDIVGSYYLQGILDEY
IPDQLISTLGMITIGLIITYIIQQVMAFAKEYLLAVLSLRLVIDVILSYIKHIFTLPMSFFATRRTGEITSRFTDANQII
DAVASTIFSIFLDMTMVILVGGVLLAQNNNLFFLTLLSIPIYAIIIFAFLKPFEKMNHEVMESNAVVSSSIIEDINGMET
IKSLTSESARYQNIDSEFVDYLEKNFKLHKYSAIQTALKSGAKLILNVVILWYGSRLVMDNKISVGQLITFNALLSYFSN
PIENIINLQSKLQSARVANTRLNEVYLVESEFEKDGDLSENSFLDGDISFENLSYKYGFGRDTLSDINLSIKKGSKVSLV
GASGSGKTTLAKLIVNFYEPNKGIVRINGNDLKVIDKTALRRYISYLPQQAYVFSGSIMDNLVLGAKEGTSQEDIIRACE
IAEIRSDIEQMPQGYQTELSDGAGISGGQKQRIALARALLTQAPVLILDEATSSLDILTEKKIISNLLQMTEKTIIFVAH
RLSISQRTDEVIVMDQGKIVEQGTHKELLAKQGFYYNLFN

Nucleotide

• Length: 2283 bp

>NTDB_id=713628 NPS16_RS01315 WP_002271629.1 281843..284125(+) (comA/nlmT) [Streptococcus mutans strain COCC33-14]
ATGAAACAAGTTATTTATGTTGTTTTAATCGTCATAGCCGTTAACATTCTCTTAGAGGTTATCAAAAGAGTAACAAAAAG
GGGAGGGACAGTTTCGTCATCTAATCCTTTACCAGATGGGCAGTCTAAGTTGTTTTGGCGCAGACATTATAAGCTAGTAC
CTCAGATTGATACCAGAGACTGTGGGCCGGCAGTGCTGGCATCTGTTGCAAAGCATTACGGATCTAACTACTCTATCGCT
TATCTGCGGGAACTCTCAAAGACTAACAAGCAGGGAACAACAGCTCTTGGCATTGTTGAAGCTGCTAAAAAGTTAGGCTT
TGAAACACGCTCTATCAAGGCGGATATGACGCTTTTTGATTATAATGATTTGACCTATCCTTTTATCGTCCATGTGATTA
AAGGAAAACGTCTGCAGCATTATTATGTCGTCTATGGCAGCCAGAATAATCAGCTGATTATTGGAGATCCTGATCCTTCA
GTTAAGGTGACTAGGATGAGTAAGGAACGCTTTCAATCAGAGTGGACAGGCCTTGCAATTTTCCTAGCTCCTCAGCCTAA
CTATAAGCCTCATAAAGGTGAAAAAAATGGTTTGTCTAATTTCTTCCCGTTGATCTTTAAGCAGAAAGCTTTGATGACTT
ATATTATCATAGCTAGCTTGATTGTGACGCTCATTGATATTGTCGGATCATACTATCTCCAAGGAATATTGGACGAGTAC
ATTCCTGATCAGCTGATTTCAACTTTAGGAATGATTACGATTGGTCTGATAATAACCTATATTATCCAGCAGGTCATGGC
TTTTGCAAAAGAATACCTCTTGGCCGTACTCAGTTTGCGTTTAGTCATTGATGTTATCCTGTCTTATATCAAACATATTT
TTACGCTTCCTATGTCTTTCTTTGCGACAAGGCGAACAGGAGAAATCACGTCTCGTTTTACAGATGCCAATCAGATTATT
GATGCTGTAGCGTCAACCATCTTTTCAATCTTTTTAGATATGACTATGGTGATTTTGGTTGGCGGGGTTTTGTTGGCGCA
AAACAATAACCTTTTCTTTCTAACCTTGCTCTCCATTCCGATTTATGCCATCATTATTTTTGCTTTCTTGAAACCCTTTG
AGAAAATGAATCACGAAGTGATGGAAAGCAATGCTGTGGTAAGTTCTTCTATCATTGAAGATATCAATGGGATGGAAACC
ATTAAATCACTCACAAGTGAGTCCGCTCGTTATCAAAACATTGATAGTGAATTTGTTGATTATTTGGAGAAAAACTTTAA
GCTACACAAGTATAGTGCCATTCAAACCGCATTAAAAAGCGGTGCTAAGCTTATCCTCAATGTTGTCATTCTCTGGTATG
GCTCTCGTCTAGTTATGGATAATAAAATCTCAGTTGGTCAGCTTATCACCTTTAATGCTTTGCTGTCTTATTTCTCAAAT
CCAATTGAAAATATTATCAATCTGCAATCCAAACTGCAGTCAGCTCGCGTTGCCAATACACGTCTTAATGAGGTCTATCT
TGTCGAATCTGAATTTGAAAAAGACGGTGATTTATCAGAAAATAGCTTTTTAGATGGTGATATTTCGTTTGAAAATCTTT
CTTATAAATATGGATTTGGGCGAGATACCTTATCAGATATTAATTTATCAATCAAAAAAGGCTCCAAGGTCAGTCTAGTT
GGAGCCAGTGGTTCTGGTAAGACAACTTTGGCTAAACTGATTGTCAATTTCTACGAGCCTAACAAGGGGATTGTTCGAAT
CAATGGCAATGATTTAAAAGTTATTGATAAGACAGCTTTGCGGCGGTATATTAGCTATTTGCCGCAACAGGCCTATGTTT
TTAGTGGCTCTATTATGGATAATCTCGTTTTAGGAGCTAAAGAAGGAACGAGTCAGGAAGACATTATTCGTGCTTGTGAA
ATTGCTGAAATCCGCTCGGACATTGAACAAATGCCTCAGGGCTATCAGACAGAGTTATCAGATGGTGCCGGTATTTCTGG
CGGTCAAAAACAGCGGATTGCTTTAGCTAGGGCCTTATTAACACAGGCACCGGTTTTGATTCTGGATGAAGCCACCAGCA
GTCTTGATATTTTGACAGAAAAGAAAATTATCAGCAATCTCTTACAGATGACGGAGAAAACAATAATTTTTGTTGCCCAC
CGCTTAAGCATTTCACAGCGTACTGACGAAGTCATTGTCATGGATCAAGGAAAAATTGTTGAACAAGGCACTCATAAGGA
ACTTTTAGCTAAGCAAGGTTTCTATTATAACCTGTTTAATTGA

Domains

Predicted by InterproScan.

• Peptidase C39 family (Peptidase_C39) (50-186)

• ABC transporter transmembrane region (ABC_membrane) (212-481)

• ABC transporter (ABC_tran) (544-693)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comA/nlmT	Streptococcus mutans UA159	99.737	100	0.997
comA	Streptococcus mitis NCTC 12261	65.551	94.342	0.618
comA	Streptococcus pneumoniae Rx1	64.993	94.342	0.613
comA	Streptococcus pneumoniae D39	64.993	94.342	0.613
comA	Streptococcus pneumoniae R6	64.993	94.342	0.613
comA	Streptococcus mitis SK321	64.854	94.342	0.612
comA	Streptococcus pneumoniae TIGR4	64.714	94.342	0.611
comA	Streptococcus gordonii str. Challis substr. CH1	64.575	94.342	0.609