Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   NPS16_RS01160 Genome accession   NZ_CP101986
Coordinates   251586..252308 (+) Length   240 a.a.
NCBI ID   WP_002263984.1    Uniprot ID   A0AAX1K0W7
Organism   Streptococcus mutans strain COCC33-14     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 246586..257308
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NPS16_RS01145 (NPS16_01145) - 246987..248540 (-) 1554 WP_258969043.1 ABC transporter substrate-binding protein/permease -
  NPS16_RS01150 (NPS16_01150) - 248692..250593 (+) 1902 WP_258969044.1 DUF2207 domain-containing protein -
  NPS16_RS01155 (NPS16_01155) - 250651..251496 (+) 846 WP_002270787.1 undecaprenyl-diphosphate phosphatase -
  NPS16_RS01160 (NPS16_01160) mecA 251586..252308 (+) 723 WP_002263984.1 adaptor protein MecA Regulator
  NPS16_RS01165 (NPS16_01165) rgpG 252314..253474 (+) 1161 WP_002262748.1 rhamnose-glucose polysaccharide biosynthesis protein RgpB -
  NPS16_RS01170 (NPS16_01170) sufC 253548..254318 (+) 771 WP_002262747.1 Fe-S cluster assembly ATPase SufC -
  NPS16_RS01175 (NPS16_01175) sufD 254356..255618 (+) 1263 WP_002293727.1 Fe-S cluster assembly protein SufD -
  NPS16_RS01180 (NPS16_01180) - 255623..256852 (+) 1230 WP_002262745.1 cysteine desulfurase -
  NPS16_RS01185 (NPS16_01185) sufU 256839..257273 (+) 435 WP_002262744.1 Fe-S cluster assembly sulfur transfer protein SufU -

Sequence

Protein


Download         Length: 240 a.a.        Molecular weight: 28028.63 Da        Isoelectric Point: 4.2340

>NTDB_id=713625 NPS16_RS01160 WP_002263984.1 251586..252308(+) (mecA) [Streptococcus mutans strain COCC33-14]
MEMKQISETTLKITISMEDLEERGMELKDFLIPQEKTEEFFYTVMDELDLPENFKDSGMLSFRVTPRNDRIDVFVTKSEI
NKNLNLEDLSDFDDISKMSPEDFFNTLEETMREKGDAAALDKLAEIEKREEEKTQQEKGETKEKRDYVHFVLDFPNIQQV
ISFAKTVDYDVEASELFKESDAYHMTVLLNLEDKPDYYADLMFARMLEHAGRGTKTRAYLLEHGVQLIKADALQELQMIG

Nucleotide


Download         Length: 723 bp        

>NTDB_id=713625 NPS16_RS01160 WP_002263984.1 251586..252308(+) (mecA) [Streptococcus mutans strain COCC33-14]
ATGGAAATGAAACAAATCAGCGAAACAACATTAAAAATCACCATCAGTATGGAAGATTTAGAAGAAAGAGGCATGGAATT
AAAAGATTTCTTGATTCCGCAGGAAAAGACGGAAGAATTTTTCTATACTGTTATGGATGAGCTGGACTTGCCTGAAAATT
TCAAGGACAGTGGGATGTTAAGCTTTCGAGTAACACCAAGGAATGATCGCATTGATGTTTTTGTCACTAAGTCAGAAATC
AATAAAAATCTTAATTTGGAGGATTTGTCTGATTTTGATGATATTTCAAAAATGTCCCCGGAGGATTTCTTTAATACCTT
GGAGGAAACCATGCGTGAAAAAGGGGATGCTGCAGCTCTGGATAAATTGGCTGAAATTGAAAAAAGAGAAGAAGAGAAGA
CTCAGCAGGAAAAAGGTGAAACTAAGGAAAAAAGAGATTACGTTCACTTTGTGCTGGATTTTCCTAATATTCAGCAAGTC
ATAAGTTTTGCTAAGACAGTTGACTATGATGTAGAGGCTTCAGAACTTTTTAAGGAGTCTGACGCTTATCACATGACTGT
TTTGCTTAATCTCGAAGATAAACCTGACTATTATGCTGATCTTATGTTTGCAAGAATGTTGGAGCATGCTGGTAGAGGAA
CAAAGACACGTGCTTATCTATTAGAACATGGAGTTCAGCTCATTAAAGCAGATGCTCTGCAAGAATTACAAATGATTGGA
TAA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-236)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Streptococcus mutans UA159

99.583

100

0.996
  mecA Streptococcus thermophilus LMD-9

57.787

100

0.588
  mecA Streptococcus thermophilus LMG 18311

57.377

100

0.583
  mecA Streptococcus pneumoniae Rx1

48.571

100

0.496
  mecA Streptococcus pneumoniae D39

48.571

100

0.496
  mecA Streptococcus pneumoniae R6

48.571

100

0.496
  mecA Streptococcus pneumoniae TIGR4

48.571

100

0.496