Detailed information    

insolico Bioinformatically predicted

Overview

Name   comD/blpH   Type   Regulator
Locus tag   NPS17_RS08720 Genome accession   NZ_CP101985
Coordinates   1842789..1844114 (-) Length   441 a.a.
NCBI ID   WP_002267940.1    Uniprot ID   -
Organism   Streptococcus mutans strain COCC33-14R     
Function   phosphorylation of ComE; regulation of comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1837789..1849114
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NPS17_RS08690 (NPS17_08690) comB 1838461..1839333 (+) 873 WP_374684427.1 HlyD family efflux transporter periplasmic adaptor subunit Regulator
  NPS17_RS10135 comB 1839323..1839475 (+) 153 WP_372552041.1 hypothetical protein Regulator
  NPS17_RS08695 (NPS17_08695) - 1839736..1839879 (-) 144 WP_002263740.1 hypothetical protein -
  NPS17_RS08700 (NPS17_08700) - 1840171..1841193 (-) 1023 WP_258968990.1 thioredoxin family protein -
  NPS17_RS08705 (NPS17_08705) - 1841678..1841866 (-) 189 WP_002270918.1 Blp family class II bacteriocin -
  NPS17_RS08710 (NPS17_08710) - 1842030..1842242 (-) 213 WP_002264173.1 Blp family class II bacteriocin -
  NPS17_RS08715 (NPS17_08715) comC/blpC 1842507..1842647 (+) 141 WP_002270250.1 ComC/BlpC family leader-containing pheromone/bacteriocin Regulator
  NPS17_RS08720 (NPS17_08720) comD/blpH 1842789..1844114 (-) 1326 WP_002267940.1 sensor histidine kinase Regulator
  NPS17_RS08725 (NPS17_08725) comE/blpR 1844111..1844863 (-) 753 WP_002270252.1 response regulator transcription factor Regulator
  NPS17_RS08730 (NPS17_08730) - 1845334..1845972 (-) 639 WP_002271525.1 VTT domain-containing protein -
  NPS17_RS08735 (NPS17_08735) - 1846020..1846646 (-) 627 WP_002273094.1 hypothetical protein -
  NPS17_RS08740 (NPS17_08740) der 1846721..1848031 (-) 1311 WP_002262117.1 ribosome biogenesis GTPase Der -
  NPS17_RS08745 (NPS17_08745) dnaI 1848044..1848943 (-) 900 WP_002273096.1 primosomal protein DnaI -

Sequence

Protein


Download         Length: 441 a.a.        Molecular weight: 50538.74 Da        Isoelectric Point: 9.8155

>NTDB_id=713597 NPS17_RS08720 WP_002267940.1 1842789..1844114(-) (comD/blpH) [Streptococcus mutans strain COCC33-14R]
MNEALMILSNGLLTYLTVLFLLFLFSKVSNVTLSKKELTLFSISNFLIMIAVTMVNVNLFYPAEPLYFIVLSIYLNRQNS
LSLNIFYGLLPVASSDLFRRAIIFFILDGNQGIVMDSSIITTYMIEFAGIALSYLFLSVFNVDIGRLKDSLTKMKVKKRL
IPMNITMLLYYLLIQALYIIESYNVIPTLKFRKFVVIVYLILFLILISFLSQYTKQKVQNEIMAQKEAQIRNITQYSQQI
ESLYKDIRSFRHDYLNILTSLRLGIENKDLASIEKIYHQILEKTGHQLQDTRYNIGHLANIQNDAVKGILSAKILEAQNK
KIAVNVEVSGKIQLPDMELLDFITILSILCDNAIEAALESLKPEIQLAFFKKNGSIVFIIQNSSKEKQIDVSKIFKENYS
TKGSNRGIGLAKVNHILEHYPKTSLQTSSHHHLFKQLLIMK

Nucleotide


Download         Length: 1326 bp        

>NTDB_id=713597 NPS17_RS08720 WP_002267940.1 1842789..1844114(-) (comD/blpH) [Streptococcus mutans strain COCC33-14R]
ATGAATGAAGCCTTAATGATACTTTCAAATGGTTTATTAACTTATCTAACCGTTCTATTTCTCTTGTTTCTATTTTCTAA
GGTAAGTAATGTCACTTTATCGAAAAAGGAATTAACTCTTTTTTCGATAAGCAATTTTCTGATAATGATTGCTGTTACGA
TGGTAAATGTAAACCTGTTTTATCCTGCAGAGCCTCTTTATTTTATAGTTTTATCAATTTATCTTAATAGACAGAATAGT
CTTTCTCTAAATATATTTTATGGTCTGCTGCCTGTTGCCAGTTCTGACTTGTTTAGGCGGGCAATCATATTCTTTATCTT
GGATGGAAATCAAGGAATTGTAATGGACAGTAGCATTATAACCACCTATATGATCGAGTTTGCAGGAATAGCGCTAAGTT
ACCTCTTTCTAAGTGTGTTCAATGTTGATATTGGTCGACTTAAAGATAGTTTGACCAAGATGAAGGTCAAAAAACGCTTG
ATCCCAATGAATATTACTATGCTTCTATACTACCTTTTAATACAGGCATTGTATATTATAGAGAGTTATAATGTGATACC
GACTTTAAAATTTCGTAAATTTGTCGTTATTGTCTATCTTATTTTATTTTTGATTCTGATCTCATTTTTAAGCCAATATA
CCAAACAAAAGGTTCAAAATGAGATAATGGCACAAAAGGAAGCTCAGATTCGAAATATCACCCAGTATAGTCAGCAAATA
GAATCTCTTTACAAGGATATTCGAAGTTTCCGCCATGATTATCTGAATATTTTAACTAGCCTCAGATTAGGCATTGAAAA
TAAAGATTTAGCTAGTATTGAAAAGATTTACCATCAAATCTTAGAAAAAACAGGACATCAATTGCAGGATACCCGTTATA
ATATCGGCCATCTAGCTAATATTCAAAACGATGCTGTCAAGGGTATCTTATCAGCAAAAATCTTAGAAGCTCAAAATAAA
AAAATTGCTGTCAATGTAGAGGTCTCAGGTAAAATACAGCTGCCTGATATGGAGTTGCTTGATTTCATTACTATACTTTC
TATCTTGTGCGATAATGCTATTGAGGCCGCTCTCGAATCACTAAAACCTGAAATTCAGTTAGCCTTTTTTAAGAAAAATG
GCAGCATAGTCTTTATCATCCAGAATTCCTCCAAAGAAAAACAAATAGATGTGAGTAAAATTTTTAAAGAAAACTATTCC
ACTAAAGGCTCCAATCGCGGTATTGGTTTAGCAAAGGTGAATCATATTCTTGAACATTATCCCAAAACCAGTTTACAAAC
AAGCAGTCATCATCATTTATTCAAGCAACTCCTAATAATGAAATAG

Domains

Predicted by InterproScan.

GHKL domain (HATPase_c_5)

(337-440)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comD/blpH Streptococcus mutans UA159

97.279

100

0.973