Detailed information    

insolico Bioinformatically predicted

Overview


Name   comB   Type   Regulator
Locus tag   NPS17_RS10135 Genome accession   NZ_CP101985
Coordinates   1839323..1839475 (+) Length   50 a.a.
NCBI ID   WP_372552041.1    Uniprot ID   -
Organism   Streptococcus mutans strain COCC33-14R     
Function   transport of ComC (predicted from homology)   
Competence regulation

Genomic Context


Location: 1834323..1844475
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NPS17_RS08660 (NPS17_08660) - 1834355..1834519 (-) 165 WP_002273566.1 class IIb bacteriocin, lactobin A/cerein 7B family -
  NPS17_RS08665 (NPS17_08665) - 1834559..1834762 (-) 204 WP_258968989.1 ComC/BlpC family leader-containing pheromone/bacteriocin -
  NPS17_RS08670 (NPS17_08670) - 1835063..1835248 (-) 186 WP_002263346.1 ComC/BlpC family leader-containing pheromone/bacteriocin -
  NPS17_RS08675 (NPS17_08675) - 1835386..1835547 (-) 162 WP_002263734.1 Blp family class II bacteriocin -
  NPS17_RS08680 (NPS17_08680) - 1835592..1835846 (-) 255 WP_002267515.1 Blp family class II bacteriocin -
  NPS17_RS08685 (NPS17_08685) - 1836234..1838448 (+) 2215 Protein_1669 peptide cleavage/export ABC transporter -
  NPS17_RS08690 (NPS17_08690) comB 1838461..1839333 (+) 873 WP_374684427.1 HlyD family efflux transporter periplasmic adaptor subunit Regulator
  NPS17_RS10135 comB 1839323..1839475 (+) 153 WP_372552041.1 hypothetical protein Regulator
  NPS17_RS08695 (NPS17_08695) - 1839736..1839879 (-) 144 WP_002263740.1 hypothetical protein -
  NPS17_RS08700 (NPS17_08700) - 1840171..1841193 (-) 1023 WP_258968990.1 thioredoxin family protein -
  NPS17_RS08705 (NPS17_08705) - 1841678..1841866 (-) 189 WP_002270918.1 Blp family class II bacteriocin -
  NPS17_RS08710 (NPS17_08710) - 1842030..1842242 (-) 213 WP_002264173.1 Blp family class II bacteriocin -
  NPS17_RS08715 (NPS17_08715) comC/blpC 1842507..1842647 (+) 141 WP_002270250.1 ComC/BlpC family leader-containing pheromone/bacteriocin Regulator
  NPS17_RS08720 (NPS17_08720) comD/blpH 1842789..1844114 (-) 1326 WP_002267940.1 sensor histidine kinase Regulator

Sequence


Protein


Download         Length: 50 a.a.        Molecular weight: 5878.96 Da        Isoelectric Point: 10.6821

>NTDB_id=713621 NPS17_RS10135 WP_372552041.1 1839323..1839475(+) (comB) [Streptococcus mutans strain COCC33-14R]
MFFKVTAKAKVSKKDSQTIKYGLQGKTITVVEKKTFFDYYKDKLLNKNQK

Nucleotide


Download         Length: 153 bp        

>NTDB_id=713621 NPS17_RS10135 WP_372552041.1 1839323..1839475(+) (comB) [Streptococcus mutans strain COCC33-14R]
ATGTTTTTTAAAGTGACAGCTAAAGCAAAAGTTTCTAAAAAAGACAGCCAAACCATTAAATACGGCCTCCAGGGTAAAAC
CATCACAGTTGTTGAAAAAAAGACTTTCTTTGATTATTATAAAGATAAACTGTTAAATAAAAATCAAAAATAA

Domains



No domain identified.



Secondary structure


Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure


Source ID Structure

Transmembrane helices


Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.



Visualization of predicted probability:


Similar proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comB Streptococcus mutans UA159

100

96

0.96

  comB/nlmE Streptococcus mutans UA159

71.739

92

0.66

  comB Streptococcus gordonii str. Challis substr. CH1

44.444

90

0.4