Detailed information NTG0713574

Bioinformatically predicted

Overview

• Name: clpX
• Type: Regulator
• Locus tag: NPS17_RS04340
• Genome accession: NZ_CP101985
• Coordinates: 911610..912842 (+)
• Length: 410 a.a.
• NCBI ID: WP_002262816.1
• Uniprot ID: A0AAX1K4W9
• Organism: Streptococcus mutans strain COCC33-14R
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 906610..917842

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
NPS17_RS04315 (NPS17_04315)	-	907682..908857 (-)	1176	WP_002271714.1	hydroxymethylglutaryl-CoA synthase	-
NPS17_RS04320 (NPS17_04320)	-	909065..909904 (+)	840	WP_258969179.1	thymidylate synthase	-
NPS17_RS04325 (NPS17_04325)	pnuC	910021..910800 (+)	780	WP_002266473.1	nicotinamide riboside transporter PnuC	-
NPS17_RS04330 (NPS17_04330)	-	910885..911397 (+)	513	WP_082999592.1	dihydrofolate reductase	-
NPS17_RS04335 (NPS17_04335)	-	911415..911585 (+)	171	WP_002262815.1	hypothetical protein	-
NPS17_RS04340 (NPS17_04340)	clpX	911610..912842 (+)	1233	WP_002262816.1	ATP-dependent Clp protease ATP-binding subunit ClpX	Regulator
NPS17_RS04345 (NPS17_04345)	yihA	912858..913451 (+)	594	WP_168742335.1	ribosome biogenesis GTP-binding protein YihA/YsxC	-
NPS17_RS04350 (NPS17_04350)	-	913788..915164 (+)	1377	WP_168742333.1	amino acid permease	-
NPS17_RS04355 (NPS17_04355)	mmuM	915174..916124 (+)	951	WP_002303868.1	homocysteine S-methyltransferase	-
NPS17_RS04360 (NPS17_04360)	-	916258..917520 (-)	1263	WP_002283146.1	PLP-dependent aminotransferase family protein	-

Sequence

Protein

• Length: 410 a.a.
• Molecular weight: 45181.65 Da
• Isoelectric Point: 4.4495

>NTDB_id=713574 NPS17_RS04340 WP_002262816.1 911610..912842(+) (clpX) [Streptococcus mutans strain COCC33-14R]
MAGNRTNDVTVHCSFCGKNQDEVKKIIAGNGVFICNECVELSQEIIREELAEEVLADLSEVPKPKELLAILDSYVIGQDR
AKRALAVAVYNHYKRISFTESQDDQDVDLQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATALTEAGYVGEDVENI
LLKLIQAADYNVERAERGIIYVDEIDKIAKKGENVSITRDVSGEGVQQALLKIIEGTVASVPPQGGRKHPQQEMIQIDTK
NILFIVGGAFDGIEDIVKQRLGEKIIGFGQNNKKIDDQSSYMQEIISEDIQKFGLIPEFIGRLPVLAALEQLTVDDLVKI
LTEPKNALVKQYQTLLSYDGVELEFDQEALQAIAQKAIERKTGARGLRSIIEETMLDLMFEIPSQEDVTCVRITKKAVEG
TDKPILETAS

Nucleotide

• Length: 1233 bp

>NTDB_id=713574 NPS17_RS04340 WP_002262816.1 911610..912842(+) (clpX) [Streptococcus mutans strain COCC33-14R]
ATGGCTGGAAATAGAACCAATGATGTCACAGTGCATTGTTCATTCTGTGGCAAAAATCAAGATGAAGTTAAAAAAATTAT
TGCAGGTAATGGCGTTTTTATTTGCAATGAATGTGTTGAATTATCACAAGAAATTATCCGTGAAGAACTAGCAGAAGAGG
TATTGGCTGATCTTTCAGAAGTTCCAAAACCAAAAGAATTGTTGGCAATACTAGACAGTTATGTTATCGGTCAGGACCGT
GCCAAACGTGCTTTAGCAGTTGCTGTCTATAATCATTATAAGCGTATCAGTTTTACTGAGAGCCAAGACGACCAAGATGT
TGACTTACAAAAATCAAATATTCTTATGATTGGACCGACAGGTTCTGGAAAAACTTTCTTAGCACAGACTTTGGCTAAGA
GTCTCAATGTGCCCTTTGCTATTGCTGATGCAACAGCCTTGACTGAAGCGGGTTATGTAGGTGAAGATGTTGAAAACATT
TTGCTTAAATTGATTCAGGCAGCTGATTATAATGTTGAACGCGCGGAGCGTGGCATCATTTATGTTGATGAAATTGATAA
GATTGCTAAAAAAGGCGAAAATGTTTCCATCACACGTGATGTATCTGGTGAAGGTGTCCAACAAGCTCTGCTTAAGATTA
TTGAAGGAACAGTAGCTAGTGTGCCACCACAAGGTGGTCGGAAACATCCCCAACAGGAAATGATTCAAATTGATACGAAA
AACATCCTCTTCATAGTTGGTGGCGCTTTTGATGGTATTGAAGATATCGTTAAACAGCGTTTGGGTGAGAAAATTATTGG
CTTTGGTCAAAATAATAAGAAGATTGATGATCAATCTTCTTATATGCAAGAAATTATTTCAGAAGACATTCAAAAATTTG
GTCTTATTCCAGAGTTTATTGGTCGTTTGCCAGTTTTAGCTGCGCTTGAGCAATTAACGGTTGATGATTTGGTTAAGATT
TTGACAGAACCTAAAAATGCTTTAGTTAAACAATATCAGACGCTTTTATCTTATGATGGTGTTGAGCTTGAGTTTGATCA
AGAGGCGCTTCAAGCGATTGCTCAAAAGGCGATTGAACGTAAGACAGGCGCACGCGGTCTTCGCTCTATTATTGAAGAAA
CGATGCTGGATCTGATGTTTGAAATTCCGAGTCAAGAGGATGTCACTTGCGTTCGCATTACTAAGAAAGCGGTAGAAGGG
ACTGACAAACCTATTCTTGAGACAGCTTCCTAA

Domains

Predicted by InterproScan.

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (312-388)

• AAA domain (Cdc48 subfamily) (AAA_2) (110-305)

• ClpX C4-type zinc finger (zf-C4_ClpX) (12-48)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpX	Streptococcus mutans UA159	100	100	1
clpX	Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819	59.102	97.805	0.578