Detailed information NTG0713417

Bioinformatically predicted

Overview

• Name: degS
• Type: Regulator
• Locus tag: NP445_RS16745
• Genome accession: NZ_CP101938
• Coordinates: 3203854..3205029 (-)
• Length: 391 a.a.
• NCBI ID: WP_024719243.1
• Uniprot ID: A0A081LEM4
• Organism: Bacillus altitudinis strain BDGP7
• Function: phosphorylation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 3198854..3210029

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
NP445_RS16715 (NP445_16715)	-	3199031..3199450 (-)	420	WP_017357864.1	TIGR03826 family flagellar region protein	-
NP445_RS16720 (NP445_16720)	-	3199507..3200229 (-)	723	WP_285891443.1	ComF family protein	-
NP445_RS16725 (NP445_16725)	-	3200190..3200483 (-)	294	WP_008348267.1	late competence development ComFB family protein	-
NP445_RS16730 (NP445_16730)	comFA	3200548..3201927 (-)	1380	WP_370529242.1	DEAD/DEAH box helicase	Machinery gene
NP445_RS16735 (NP445_16735)	-	3202047..3202889 (-)	843	WP_024719242.1	DegV family protein	-
NP445_RS16740 (NP445_16740)	degU	3203100..3203789 (-)	690	WP_008348273.1	two-component system response regulator DegU	Regulator
NP445_RS16745 (NP445_16745)	degS	3203854..3205029 (-)	1176	WP_024719243.1	sensor histidine kinase	Regulator
NP445_RS16750 (NP445_16750)	-	3205251..3205919 (+)	669	WP_017357860.1	YigZ family protein	-
NP445_RS16755 (NP445_16755)	-	3205904..3206995 (+)	1092	WP_135226381.1	LCP family protein	-
NP445_RS16760 (NP445_16760)	-	3207030..3208097 (-)	1068	WP_024719245.1	glycosyltransferase family 4 protein	-
NP445_RS16765 (NP445_16765)	-	3208232..3209479 (-)	1248	WP_256688752.1	glycosyltransferase	-

Sequence

Protein

• Length: 391 a.a.
• Molecular weight: 45550.27 Da
• Isoelectric Point: 5.8757

>NTDB_id=713417 NP445_RS16745 WP_024719243.1 3203854..3205029(-) (degS) [Bacillus altitudinis strain BDGP7]
MTTPKMDPKLLDSIIMKMLSTVDGSKDEVFRIGEQSRQQYESLVEELKQIKQQVNEVIDFGDKLEVHTRHARNRLSEVSR
NFNKFSEEEIREAYEKAHNLQVELTMIQQREKQLRERRDDLERRLLSLQDVIERSETLVSQITVVLNYLNQDLRQVGVLL
EDAQAKQDFGLRIIEAQEEERKRVSREIHDGPAQMLANVMMRSELIERIFRDRGTEEGFKEIRSLRQNVRNALYEVRRII
YDLRPMALDDLGLIPTLRKYLNTIEEYDGKTKITFQCLGDTENERIASQFEVALFRLAQEAVTNSLKHSEAEEISVKVEV
TKDFVTLIIKDDGKGFDMKDVKTNKNKSFGLLGMKERVDLLEGKMTIDSKIGLGTFIMIRVPLTLQNKIVK

Nucleotide

• Length: 1176 bp

>NTDB_id=713417 NP445_RS16745 WP_024719243.1 3203854..3205029(-) (degS) [Bacillus altitudinis strain BDGP7]
ATGACAACACCTAAAATGGATCCGAAGTTATTGGATTCAATCATCATGAAAATGCTAAGTACAGTTGATGGCAGTAAGGA
CGAAGTATTTAGAATCGGCGAACAGTCCCGTCAACAATATGAAAGCCTAGTAGAAGAGCTCAAGCAAATTAAACAGCAAG
TCAACGAAGTAATTGATTTTGGGGATAAACTAGAAGTACATACGAGACATGCTAGAAATCGATTATCTGAGGTCAGCAGA
AACTTCAACAAATTCAGCGAAGAAGAAATACGAGAAGCCTATGAAAAAGCACATAACCTGCAAGTAGAATTGACCATGAT
CCAGCAGCGCGAAAAACAGCTGAGGGAAAGAAGAGATGATCTCGAAAGACGATTGTTAAGCTTACAAGATGTCATTGAAC
GTTCAGAAACGCTTGTGAGCCAGATCACGGTCGTTCTCAACTACTTGAACCAAGATTTACGTCAGGTCGGTGTTTTACTT
GAAGATGCTCAGGCAAAACAAGATTTTGGACTAAGAATTATTGAAGCCCAGGAAGAAGAGCGCAAAAGGGTATCACGAGA
AATCCATGATGGACCTGCTCAGATGCTGGCAAACGTGATGATGCGTTCAGAACTAATTGAACGAATTTTTAGAGACCGTG
GAACAGAAGAAGGCTTTAAAGAAATTAGAAGTCTAAGACAGAATGTGCGAAATGCACTGTACGAAGTGAGAAGAATCATT
TATGATTTAAGACCGATGGCTTTAGATGATTTGGGTCTCATTCCGACACTGCGAAAATACTTAAACACAATTGAAGAATA
TGATGGAAAAACCAAAATTACGTTCCAATGCCTAGGGGATACAGAAAATGAAAGAATTGCTTCTCAGTTCGAAGTGGCAC
TGTTTAGACTAGCCCAAGAAGCTGTCACAAATTCATTGAAGCATTCCGAAGCTGAAGAAATCTCTGTAAAAGTAGAAGTG
ACAAAAGACTTTGTCACGTTAATTATCAAAGACGATGGAAAAGGCTTTGATATGAAAGATGTGAAAACAAATAAAAACAA
ATCCTTCGGTTTACTTGGCATGAAAGAGCGCGTAGACTTACTAGAAGGTAAAATGACCATAGACTCAAAAATAGGTCTAG
GGACATTTATCATGATTAGAGTACCGTTAACATTACAAAATAAAATTGTAAAATAG

Domains

Predicted by InterproScan.

• Sensor protein DegS (DegS) (12-170)

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (291-384)

• Histidine kinase (HisKA_3) (180-248)

3D structure

• AlphaFold DB: A0A081LEM4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
degS	Bacillus subtilis subsp. subtilis str. 168	85.455	98.465	0.841