Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   PND17_RS07875 Genome accession   NZ_CP116772
Coordinates   1495605..1496249 (+) Length   214 a.a.
NCBI ID   WP_002951384.1    Uniprot ID   -
Organism   Streptococcus thermophilus strain strain TSGB 4141     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1490605..1501249
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  PND17_RS07855 (PND17_07855) stkP/pknB 1490980..1492851 (+) 1872 WP_271298435.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  PND17_RS07860 (PND17_07860) - 1493488..1493655 (+) 168 WP_271298436.1 potassium channel family protein -
  PND17_RS07865 (PND17_07865) liaF 1493910..1494608 (+) 699 WP_011226289.1 cell wall-active antibiotics response protein LiaF -
  PND17_RS07870 (PND17_07870) - 1494605..1495615 (+) 1011 WP_087010056.1 sensor histidine kinase -
  PND17_RS07875 (PND17_07875) vraR 1495605..1496249 (+) 645 WP_002951384.1 response regulator transcription factor Regulator
  PND17_RS07890 (PND17_07890) rimM 1496925..1497443 (+) 519 WP_011226286.1 ribosome maturation factor RimM -
  PND17_RS07895 (PND17_07895) trmD 1497433..1498152 (+) 720 WP_179970957.1 tRNA (guanosine(37)-N1)-methyltransferase TrmD -
  PND17_RS07900 (PND17_07900) - 1498154..1499152 (+) 999 WP_084829748.1 NAD(P)/FAD-dependent oxidoreductase -

Sequence

Protein


Download         Length: 214 a.a.        Molecular weight: 24048.39 Da        Isoelectric Point: 4.5864

>NTDB_id=712935 PND17_RS07875 WP_002951384.1 1495605..1496249(+) (vraR) [Streptococcus thermophilus strain strain TSGB 4141]
MSNKINVILVDDHEMVRLGLKSFLNLQGDVEVVGEAENGREGVDLALELRPDVVVMDLVMPELDGVQATLELLKEWPEAK
ILVLTSYLDNEKIYPVIEAGAKGYMLKTSSAAEILNSIRKVYRGEEAIETEVDNKIKYHDSHPNLHDDLTARERDILALL
AKGYDNQTIANELFISLKTVKTHVSNILGKLNVDDRTQAVVYAFRHHLVSQDDE

Nucleotide


Download         Length: 645 bp        

>NTDB_id=712935 PND17_RS07875 WP_002951384.1 1495605..1496249(+) (vraR) [Streptococcus thermophilus strain strain TSGB 4141]
ATGTCGAATAAGATTAATGTAATTTTGGTAGATGATCATGAAATGGTTCGTTTAGGCCTTAAGAGTTTCTTGAATCTCCA
AGGAGATGTAGAAGTGGTTGGAGAGGCAGAAAACGGCCGTGAGGGTGTCGATCTTGCCCTGGAGCTACGACCAGATGTCG
TTGTTATGGACCTTGTTATGCCTGAGCTAGATGGTGTTCAGGCGACTTTGGAATTGCTCAAAGAATGGCCTGAAGCTAAG
ATTCTAGTTTTGACCAGCTATTTGGACAATGAAAAAATTTATCCAGTCATTGAAGCTGGCGCCAAAGGCTATATGCTTAA
AACGAGCAGTGCAGCAGAGATTCTAAATAGTATCCGTAAGGTTTACCGTGGAGAGGAAGCTATCGAAACTGAGGTAGACA
ATAAGATTAAATACCATGATAGTCACCCGAACTTACATGATGACTTGACCGCGCGCGAACGTGATATCTTAGCCCTCCTA
GCTAAAGGCTATGACAATCAAACCATTGCTAACGAACTTTTTATTTCTTTAAAAACTGTCAAGACTCATGTGTCTAATAT
CCTTGGGAAATTAAATGTTGATGACCGTACTCAGGCTGTAGTTTATGCCTTTAGACATCATCTGGTTTCACAGGATGATG
AATAA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(7-118)

Bacterial regulatory proteins, luxR family (GerE)

(149-203)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

50.485

96.262

0.486
  degU Bacillus subtilis subsp. subtilis str. 168

36.161

100

0.379