Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   K6J64_RS00175 Genome accession   NZ_AP018775
Coordinates   39841..40515 (-) Length   224 a.a.
NCBI ID   WP_005647998.1    Uniprot ID   Q4QLV0
Organism   Haemophilus influenzae strain CHBN-III-4 isolate 12H35     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 34841..45515
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  K6J64_RS00155 (CHBNIII4_00310) hinT 36550..36900 (+) 351 WP_005627389.1 purine nucleoside phosphoramidase -
  K6J64_RS00160 (CHBNIII4_00320) - 36900..37250 (+) 351 WP_014550994.1 DUF1425 domain-containing protein -
  K6J64_RS00165 (CHBNIII4_00330) nagZ 37254..38308 (+) 1055 Protein_32 beta-N-acetylhexosaminidase -
  K6J64_RS00170 (CHBNIII4_00350) rlmC 38301..39476 (+) 1176 WP_014550995.1 23S rRNA (uracil(747)-C(5))-methyltransferase RlmC -
  K6J64_RS00175 (CHBNIII4_00360) crp 39841..40515 (-) 675 WP_005647998.1 cAMP-activated global transcriptional regulator CRP Regulator
  K6J64_RS00180 (CHBNIII4_00370) - 40500..40751 (-) 252 WP_005647999.1 YheU family protein -
  K6J64_RS00185 (CHBNIII4_00380) slmA 40773..41432 (-) 660 WP_014550996.1 nucleoid occlusion factor SlmA -
  K6J64_RS00190 (CHBNIII4_00390) dut 41436..41891 (-) 456 WP_014550997.1 dUTP diphosphatase -
  K6J64_RS00195 (CHBNIII4_00400) coaBC 41939..43141 (-) 1203 WP_014550998.1 bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase CoaBC -
  K6J64_RS00200 (CHBNIII4_00410) radC 43304..43969 (+) 666 WP_013527272.1 DNA repair protein RadC -
  K6J64_RS00205 (CHBNIII4_00420) rpmB 44183..44419 (+) 237 WP_005542826.1 50S ribosomal protein L28 -
  K6J64_RS00210 (CHBNIII4_00430) rpmG 44431..44601 (+) 171 WP_005613503.1 50S ribosomal protein L33 -

Sequence

Protein


Download         Length: 224 a.a.        Molecular weight: 25151.85 Da        Isoelectric Point: 6.8375

>NTDB_id=71089 K6J64_RS00175 WP_005647998.1 39841..40515(-) (crp) [Haemophilus influenzae strain CHBN-III-4 isolate 12H35]
MSNELTEIDEVVTSSQEEATQRDPVLDWFLTHCHLHKYPAKSTLIHAGEDATTLYYVIKGSVMVSSKDDEGKEMILTYLG
AGQFFGEAGLFDEGSKRSAWVKTKTTCEIAEISYKKYRQLIQANPEILMFLTAQLARRLQNTSRQVTNLAFLDVAGRIAQ
TLMNLAKQPEAMTHPDGMQIKITRQEIGQMVGCSRETVGRIIKMLEDQNLIHAHGKTIVVYGAR

Nucleotide


Download         Length: 675 bp        

>NTDB_id=71089 K6J64_RS00175 WP_005647998.1 39841..40515(-) (crp) [Haemophilus influenzae strain CHBN-III-4 isolate 12H35]
ATGTCAAATGAATTAACCGAAATTGATGAAGTTGTAACCTCCTCTCAAGAAGAAGCAACTCAACGAGATCCCGTTTTAGA
TTGGTTTCTTACTCACTGCCATTTGCATAAATATCCTGCAAAATCAACTTTAATTCATGCTGGGGAAGATGCGACCACGC
TGTATTATGTAATTAAAGGTTCTGTAATGGTATCTTCAAAAGATGATGAAGGCAAAGAGATGATCCTCACTTACTTAGGT
GCAGGACAATTTTTTGGCGAAGCGGGATTATTTGATGAAGGTTCAAAACGATCAGCTTGGGTAAAAACAAAAACAACATG
TGAAATTGCTGAAATTTCCTATAAGAAATATCGCCAGTTGATTCAGGCAAACCCTGAAATCTTAATGTTTCTTACTGCAC
AATTGGCAAGACGTTTGCAAAATACATCACGTCAAGTCACGAATTTGGCATTTTTAGACGTCGCAGGTCGCATCGCTCAA
ACTTTAATGAACTTAGCTAAACAGCCTGAAGCAATGACGCATCCTGATGGTATGCAAATCAAAATTACACGCCAAGAAAT
AGGGCAAATGGTGGGTTGTTCACGAGAAACTGTGGGGCGCATTATTAAGATGTTGGAGGATCAGAATCTTATCCACGCTC
ATGGAAAAACAATCGTTGTATATGGCGCAAGATAA

Domains

Predicted by InterproScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(36-124)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(156-220)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q4QLV0

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Haemophilus influenzae Rd KW20

100

100

1
  crp Vibrio cholerae strain A1552

75.49

91.071

0.687
  crp Acinetobacter baumannii D1279779

48.705

86.161

0.42

Multiple sequence alignment