Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   BV189_RS00290 Genome accession   NZ_CP116489
Coordinates   57620..59449 (-) Length   609 a.a.
NCBI ID   WP_011961832.1    Uniprot ID   -
Organism   Haemophilus influenzae strain 93P28H1     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 52620..64449
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  BV189_RS00270 (BV189_0055) - 53606..54634 (-) 1029 WP_005687497.1 zinc-binding dehydrogenase -
  BV189_RS00275 (BV189_0056) - 54795..55544 (+) 750 WP_005687499.1 GntR family transcriptional regulator -
  BV189_RS00280 (BV189_0057) uxuA 55572..56756 (+) 1185 WP_005687501.1 mannonate dehydratase -
  BV189_RS00285 (BV189_0058) - 56809..57522 (-) 714 WP_011961833.1 TerC family protein -
  BV189_RS00290 (BV189_0059) uvrC 57620..59449 (-) 1830 WP_011961832.1 excinuclease ABC subunit UvrC Machinery gene
  BV189_RS00295 (BV189_0060) kdsB 59596..60360 (-) 765 WP_005687509.1 3-deoxy-manno-octulosonate cytidylyltransferase -
  BV189_RS00300 (BV189_0061) lpxK 60431..61430 (-) 1000 Protein_58 tetraacyldisaccharide 4'-kinase -
  BV189_RS00305 (BV189_0062) msbA 61503..63266 (-) 1764 WP_005687513.1 lipid A ABC transporter ATP-binding protein/permease MsbA -

Sequence

Protein


Download         Length: 609 a.a.        Molecular weight: 69602.50 Da        Isoelectric Point: 9.1382

>NTDB_id=710329 BV189_RS00290 WP_011961832.1 57620..59449(-) (uvrC) [Haemophilus influenzae strain 93P28H1]
MFNYKKFLADVSHEPGVYRMYDDKDQVIYVGKAKDLKKRLSSYFRKNLSSKKTEALVASIHHIDTMLTSSETEALLLEHN
FIKLYQPRYNVLLRDDKSYPFILLTKERHPRITSYRGSKKFAGEYFGPYPHAGAVRETLSLLQKLFPVRQCENSVYSNRS
RPCLQYQIGRCSAPCVQGYVSDEEYNQQVELARLFLQGKDQLVLDYLIGKMEQASRNLDFEQAARYRDQIQAVRSVIEKQ
FVSNERLDDMDIMSIAYQHGLACVQVMFIRQGKVLGNRSYFPKVPANTDLSELTETFVGQFYLQGHQGRSIPNSIIVDRQ
LAEKSELEQLLTDQAGRKVTIQESVKGDKSKYLQLAQVNAKAALNVQLKQSSRMSERYQALCDLLNLPEIKRMECFDISH
TMGNQTVASCVVFNQEGPLKSDYRRFNIEGITGGDDYAAMEQALQKRYERDLEEDKIPDIIFIDGGKGQLNRALNVFQHL
QVKWDKNRPHLIGVAKGVDRRAGQEVLIISKQEREIHLPDDSLALHLIQHIRDESHNHAISGHRKKRQKAFTQSGLETIE
GVGAKRRQALLKYLGGLQGVKKATLDEIASVPGISLKLAETIFETLKND

Nucleotide


Download         Length: 1830 bp        

>NTDB_id=710329 BV189_RS00290 WP_011961832.1 57620..59449(-) (uvrC) [Haemophilus influenzae strain 93P28H1]
ATGTTCAATTACAAAAAATTCCTCGCTGATGTCTCTCACGAACCTGGTGTTTATCGTATGTATGATGATAAAGATCAGGT
TATTTATGTTGGGAAAGCAAAGGATCTAAAAAAACGTCTTTCAAGCTATTTTCGTAAAAACCTGAGCAGTAAAAAAACAG
AGGCGTTGGTGGCATCAATTCATCATATTGACACCATGCTAACTTCATCTGAAACGGAAGCTTTGCTGCTAGAGCATAAT
TTTATCAAGCTTTATCAGCCTCGCTATAACGTATTATTGCGTGATGATAAATCCTATCCATTTATTTTATTAACCAAAGA
ACGTCACCCAAGAATCACTTCCTATCGTGGGTCTAAAAAATTTGCCGGTGAATATTTCGGGCCTTATCCTCATGCGGGAG
CCGTGCGTGAAACTTTATCGCTTTTGCAAAAACTTTTCCCTGTTCGACAATGTGAAAATTCCGTTTATTCCAACCGCTCT
CGTCCTTGTTTGCAATATCAAATTGGGCGTTGTTCTGCACCTTGTGTACAGGGATATGTTTCTGATGAAGAATATAATCA
GCAAGTTGAATTAGCCCGTTTATTTTTACAAGGCAAAGATCAACTGGTGTTAGATTATTTAATCGGGAAAATGGAGCAGG
CAAGCAGAAATTTAGATTTTGAACAGGCGGCTCGTTATCGCGATCAAATTCAGGCGGTGCGTTCGGTTATTGAAAAACAA
TTTGTATCCAATGAACGTTTAGATGATATGGATATTATGTCCATCGCTTACCAACACGGTTTAGCCTGTGTACAGGTGAT
GTTTATTCGTCAAGGAAAAGTGCTAGGCAATCGCAGTTATTTCCCAAAAGTCCCCGCCAATACGGATTTATCGGAACTTA
CCGAAACTTTTGTGGGGCAATTTTATTTACAAGGTCATCAAGGACGAAGTATCCCGAATAGCATTATTGTCGATCGTCAA
TTAGCTGAAAAATCAGAGCTTGAGCAACTTCTTACGGATCAAGCTGGCAGAAAAGTGACGATTCAAGAAAGCGTAAAAGG
CGATAAGAGTAAATATTTACAGCTCGCACAGGTTAATGCTAAAGCGGCCTTAAATGTACAACTTAAACAATCTTCACGAA
TGTCAGAGCGTTATCAAGCGTTGTGTGATCTGTTAAATCTCCCTGAAATTAAGCGTATGGAGTGTTTCGATATAAGCCAC
ACGATGGGAAATCAAACGGTAGCATCTTGTGTTGTTTTTAATCAAGAAGGCCCACTGAAATCTGATTATCGTCGTTTTAA
TATTGAAGGCATTACTGGTGGGGATGATTATGCAGCAATGGAACAAGCGTTGCAGAAACGTTATGAGCGTGATTTAGAAG
AAGATAAAATTCCCGATATTATTTTTATTGATGGTGGAAAAGGGCAATTAAATCGTGCGCTGAACGTGTTCCAACATCTT
CAAGTAAAATGGGATAAAAATAGACCGCACTTAATTGGCGTGGCAAAAGGTGTGGATCGTCGAGCAGGGCAGGAAGTACT
GATCATCAGCAAACAAGAGCGCGAAATTCATTTGCCTGATGATAGTTTGGCATTGCATTTGATTCAACACATCCGTGATG
AAAGTCATAATCACGCCATAAGCGGACACCGTAAAAAACGTCAAAAAGCCTTTACACAAAGTGGTTTAGAAACTATTGAA
GGTGTGGGCGCTAAACGTCGTCAGGCTTTACTGAAATATCTTGGCGGTTTACAAGGTGTGAAAAAGGCGACCTTAGATGA
AATAGCCTCTGTACCAGGAATTTCCCTTAAACTTGCTGAAACGATTTTTGAAACGCTCAAAAACGATTAA

Domains

Predicted by InterProScan.

Helix-hairpin-helix domain (HHH_5)

(556-607)

UvrB/uvrC motif (UVR)

(210-234)

GIY-YIG catalytic domain (GIY-YIG)

(15-90)

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(384-540)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Streptococcus pneumoniae TIGR4

38.151

97.701

0.373
  uvrC Streptococcus pneumoniae R6

37.815

97.701

0.369
  uvrC Streptococcus pneumoniae D39

37.815

97.701

0.369