Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   E5Q65_RS05610 Genome accession   NZ_CP116480
Coordinates   1109899..1110555 (-) Length   218 a.a.
NCBI ID   WP_000611328.1    Uniprot ID   P66797
Organism   Escherichia coli strain GTEN_24     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1104899..1115555
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  E5Q65_RS05580 yecA 1106150..1106815 (-) 666 WP_000847882.1 UPF0149 family protein YecA -
  E5Q65_RS05600 pgsA 1107465..1108013 (-) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  E5Q65_RS05605 uvrC 1108070..1109902 (-) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  E5Q65_RS05610 letA 1109899..1110555 (-) 657 WP_000611328.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  E5Q65_RS24850 - 1110697..1110813 (+) 117 WP_001302039.1 hypothetical protein -
  E5Q65_RS05615 yecU 1110851..1111027 (+) 177 WP_000590344.1 protein YecU -
  E5Q65_RS05620 yecF 1111014..1111238 (+) 225 WP_000106474.1 DUF2594 family protein YecF -
  E5Q65_RS05625 sdiA 1111305..1112027 (-) 723 WP_001154265.1 transcriptional regulator SdiA -
  E5Q65_RS05630 tcyN 1112257..1113009 (-) 753 WP_001272994.1 L-cystine ABC transporter ATP-binding protein TcyN -
  E5Q65_RS05635 tcyL 1113006..1113674 (-) 669 WP_001158220.1 cystine ABC transporter permease -
  E5Q65_RS05640 dcyD 1113689..1114675 (-) 987 WP_001128215.1 D-cysteine desulfhydrase -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23862.63 Da        Isoelectric Point: 6.9614

>NTDB_id=710257 E5Q65_RS05610 WP_000611328.1 1109899..1110555(-) (letA) [Escherichia coli strain GTEN_24]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRANAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=710257 E5Q65_RS05610 WP_000611328.1 1109899..1110555(-) (letA) [Escherichia coli strain GTEN_24]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTTGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGTCGGGCAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P66797

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

50.725

94.954

0.482
  letA Legionella pneumophila strain ERS1305867

50.725

94.954

0.482