Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   PL330_RS09635 Genome accession   NZ_CP116411
Coordinates   2047818..2048474 (+) Length   218 a.a.
NCBI ID   WP_000611328.1    Uniprot ID   P66797
Organism   Escherichia coli strain HH45     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2042818..2053474
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  PL330_RS09605 (PL330_09605) dcyD 2043697..2044683 (+) 987 WP_001128215.1 D-cysteine desulfhydrase -
  PL330_RS09610 (PL330_09610) tcyL 2044698..2045366 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  PL330_RS09615 (PL330_09615) tcyN 2045363..2046115 (+) 753 WP_001272992.1 L-cystine ABC transporter ATP-binding protein TcyN -
  PL330_RS09620 (PL330_09620) sdiA 2046345..2047067 (+) 723 WP_001154288.1 transcriptional regulator SdiA -
  PL330_RS09625 (PL330_09625) yecF 2047135..2047359 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  PL330_RS09630 (PL330_09630) yecU 2047346..2047522 (-) 177 WP_000590347.1 protein YecU -
  PL330_RS09635 (PL330_09635) letA 2047818..2048474 (+) 657 WP_000611328.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  PL330_RS09640 (PL330_09640) uvrC 2048471..2050303 (+) 1833 WP_001283427.1 excinuclease ABC subunit UvrC Machinery gene
  PL330_RS09645 (PL330_09645) pgsA 2050360..2050908 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  PL330_RS09665 (PL330_09665) yecA 2051558..2052223 (+) 666 WP_000847882.1 UPF0149 family protein YecA -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23862.63 Da        Isoelectric Point: 6.9614

>NTDB_id=710110 PL330_RS09635 WP_000611328.1 2047818..2048474(+) (letA) [Escherichia coli strain HH45]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRANAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=710110 PL330_RS09635 WP_000611328.1 2047818..2048474(+) (letA) [Escherichia coli strain HH45]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGGCAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
AATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P66797

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

50.725

94.954

0.482
  letA Legionella pneumophila strain ERS1305867

50.725

94.954

0.482