Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   PL329_RS11530 Genome accession   NZ_CP116409
Coordinates   2386311..2386967 (+) Length   218 a.a.
NCBI ID   WP_000611335.1    Uniprot ID   Q3Z2T8
Organism   Escherichia coli strain HH97     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2381311..2391967
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  PL329_RS11500 (PL329_11500) dcyD 2382190..2383176 (+) 987 WP_001373912.1 D-cysteine desulfhydrase -
  PL329_RS11505 (PL329_11505) tcyL 2383191..2383859 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  PL329_RS11510 (PL329_11510) tcyN 2383856..2384608 (+) 753 WP_001461119.1 L-cystine ABC transporter ATP-binding protein TcyN -
  PL329_RS11515 (PL329_11515) sdiA 2384838..2385560 (+) 723 WP_001154267.1 transcriptional regulator SdiA -
  PL329_RS11520 (PL329_11520) yecF 2385628..2385852 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  PL329_RS11525 (PL329_11525) yecU 2385839..2386015 (-) 177 WP_000590344.1 protein YecU -
  PL329_RS24650 - 2386053..2386169 (-) 117 WP_001302039.1 hypothetical protein -
  PL329_RS11530 (PL329_11530) letA 2386311..2386967 (+) 657 WP_000611335.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  PL329_RS11535 (PL329_11535) uvrC 2386964..2388796 (+) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  PL329_RS11540 (PL329_11540) pgsA 2388853..2389401 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  PL329_RS11560 (PL329_11560) yecA 2390050..2390715 (+) 666 WP_271711304.1 UPF0149 family protein YecA -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23892.65 Da        Isoelectric Point: 6.9614

>NTDB_id=710038 PL329_RS11530 WP_000611335.1 2386311..2386967(+) (letA) [Escherichia coli strain HH97]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRTNAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=710038 PL329_RS11530 WP_000611335.1 2386311..2386967(+) (letA) [Escherichia coli strain HH97]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGACAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-115)

Bacterial regulatory proteins, luxR family (GerE)

(149-204)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q3Z2T8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

51.208

94.954

0.486
  letA Legionella pneumophila strain ERS1305867

51.208

94.954

0.486