Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   PL328_RS09235 Genome accession   NZ_CP116405
Coordinates   1923955..1924611 (+) Length   218 a.a.
NCBI ID   WP_000611328.1    Uniprot ID   P66797
Organism   Escherichia coli strain HH107     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1918955..1929611
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  PL328_RS09205 (PL328_09205) dcyD 1919834..1920820 (+) 987 WP_001128215.1 D-cysteine desulfhydrase -
  PL328_RS09210 (PL328_09210) tcyL 1920835..1921503 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  PL328_RS09215 (PL328_09215) tcyN 1921500..1922252 (+) 753 WP_001272994.1 L-cystine ABC transporter ATP-binding protein TcyN -
  PL328_RS09220 (PL328_09220) sdiA 1922482..1923204 (+) 723 WP_001154273.1 transcriptional regulator SdiA -
  PL328_RS09225 (PL328_09225) yecF 1923272..1923496 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  PL328_RS09230 (PL328_09230) yecU 1923483..1923659 (-) 177 WP_000590344.1 protein YecU -
  PL328_RS24945 - 1923697..1923813 (-) 117 WP_001302039.1 hypothetical protein -
  PL328_RS09235 (PL328_09235) letA 1923955..1924611 (+) 657 WP_000611328.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  PL328_RS09240 (PL328_09240) uvrC 1924608..1926440 (+) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  PL328_RS09245 (PL328_09245) pgsA 1926497..1927045 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  PL328_RS09265 (PL328_09265) yecA 1927695..1928360 (+) 666 WP_000847902.1 UPF0149 family protein YecA -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23862.63 Da        Isoelectric Point: 6.9614

>NTDB_id=709944 PL328_RS09235 WP_000611328.1 1923955..1924611(+) (letA) [Escherichia coli strain HH107]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRANAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=709944 PL328_RS09235 WP_000611328.1 1923955..1924611(+) (letA) [Escherichia coli strain HH107]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGTCGGGCAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P66797

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

50.725

94.954

0.482
  letA Legionella pneumophila strain ERS1305867

50.725

94.954

0.482