Detailed information    

insolico Bioinformatically predicted

Overview

Name   comE   Type   Machinery gene
Locus tag   K6J66_RS02900 Genome accession   NZ_AP018771
Coordinates   584909..586252 (+) Length   447 a.a.
NCBI ID   WP_038439361.1    Uniprot ID   -
Organism   Haemophilus influenzae strain CHBN-II-8 isolate 10H27     
Function   type IV pilus biogenesis and function (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 579909..591252
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  K6J66_RS02875 (CHBNII8_05440) - 579974..582568 (-) 2595 WP_038439366.1 penicillin-binding protein 1A -
  K6J66_RS02880 (CHBNII8_05450) comA 582667..583464 (+) 798 WP_038439365.1 pilus assembly protein PilM Machinery gene
  K6J66_RS02885 (CHBNII8_05460) comB 583465..583971 (+) 507 WP_038439363.1 competence protein ComB Machinery gene
  K6J66_RS02890 (CHBNII8_05470) comC 583968..584489 (+) 522 WP_005662592.1 competence protein ComC Machinery gene
  K6J66_RS02895 (CHBNII8_05480) comD 584486..584899 (+) 414 WP_032823984.1 pilus assembly protein PilP Machinery gene
  K6J66_RS02900 (CHBNII8_05490) comE 584909..586252 (+) 1344 WP_038439361.1 type IV pilus secretin PilQ family protein Machinery gene
  K6J66_RS02905 (CHBNII8_05500) - 586249..586473 (+) 225 Protein_554 transposase -
  K6J66_RS02910 (CHBNII8_05510) - 586605..587291 (+) 687 WP_038439360.1 ComF family protein -
  K6J66_RS02915 (CHBNII8_05520) nfuA 587367..587963 (+) 597 WP_038439359.1 Fe-S biogenesis protein NfuA -
  K6J66_RS02920 (CHBNII8_05530) nudC 588030..588824 (+) 795 WP_038439358.1 NAD(+) diphosphatase -
  K6J66_RS02925 (CHBNII8_05540) - 588860..589450 (+) 591 WP_005662597.1 YjaG family protein -
  K6J66_RS02930 (CHBNII8_05550) - 589590..589862 (+) 273 WP_005630954.1 HU family DNA-binding protein -

Sequence

Protein


Download         Length: 447 a.a.        Molecular weight: 49326.86 Da        Isoelectric Point: 8.1365

>NTDB_id=70965 K6J66_RS02900 WP_038439361.1 584909..586252(+) (comE) [Haemophilus influenzae strain CHBN-II-8 isolate 10H27]
MKKYLLKCGYFLVCFCLPLIVFANPKTDNERFFICLSQAPLAQILEQLAFQQDVNLVMGERLEGNISLKLNNIDMPRLLK
IIAKSKKITLNKDEGIYYLNGGLSGKGQVAGNLTTNEPHLVSHTVKLHFAKASELMKSLTTGSGSLLSPAGSITFDDRSN
LLVIQDEPRFVQNIKKLIAEMDKPIEQIAIEARIVTITDESLKELGVRWGIFNPTENARRVAGSLTGNSFENIADNLNVN
FATTTTPAGSIALQVAKINGRLLDLELSALERENNVEIIASPRLLTTNKKSASIKQGTEIPYVVSNTRNDTQSVEFREAV
LGLEVTPHISKDNNILLDLLVSQNSPGSRVAYGQNEVVSIDKQEINTQVFAKDGETIVLGGVFHDTITKSEDKVPLLGDI
PVIKRLFSKESERHQKRELVIFVTPHILKAGETLEALKQKSAGKKLQ

Nucleotide


Download         Length: 1344 bp        

>NTDB_id=70965 K6J66_RS02900 WP_038439361.1 584909..586252(+) (comE) [Haemophilus influenzae strain CHBN-II-8 isolate 10H27]
ATGAAGAAATATCTTTTAAAGTGCGGTTATTTTTTAGTATGTTTTTGTTTGCCATTAATCGTTTTTGCTAATCCTAAAAC
AGATAACGAACGTTTTTTTATTTGTTTATCGCAAGCACCTTTAGCTCAAATACTGGAGCAATTAGCTTTTCAACAAGATG
TGAATTTAGTGATGGGTGAGAGGTTAGAAGGCAATATTTCTTTGAAATTAAACAATATTGATATGCCACGTTTGCTAAAA
ATAATCGCAAAAAGTAAGAAGATTACTTTGAATAAAGATGAGGGTATTTACTATCTGAATGGAGGGCTATCAGGCAAAGG
TCAAGTTGCAGGAAATCTTACTACAAATGAACCGCACTTAGTGAGTCACACGGTAAAACTCCATTTTGCTAAAGCCTCTG
AATTAATGAAATCCTTAACAACAGGAAGTGGATCTTTGCTTTCTCCTGCGGGGAGCATTACCTTTGATGATCGCAGTAAT
TTGCTGGTTATTCAGGATGAACCTCGTTTTGTGCAAAATATCAAAAAACTGATTGCTGAAATGGATAAGCCTATTGAACA
GATCGCTATTGAAGCGCGAATTGTGACAATTACGGATGAGAGTTTGAAAGAACTTGGCGTTCGGTGGGGGATTTTTAATC
CAACTGAAAATGCAAGACGAGTTGCGGGCAGCCTTACAGGCAATAGCTTTGAAAATATTGCGGATAATCTTAATGTAAAT
TTTGCGACAACGACGACACCTGCTGGCTCTATAGCATTACAAGTCGCGAAAATTAATGGGCGATTGCTTGATTTAGAATT
GAGTGCGTTGGAGCGTGAAAATAATGTAGAAATTATTGCAAGTCCTCGCTTACTCACTACCAATAAGAAAAGTGCAAGCA
TTAAACAGGGGACAGAAATTCCTTACGTCGTGAGTAATACTCGTAACGATACGCAGTCTGTGGAATTTCGTGAGGCGGTG
CTTGGTTTGGAAGTGACGCCACATATTTCTAAAGATAACAATATCTTACTTGATTTATTGGTGAGTCAAAATTCCCCTGG
TTCTCGTGTCGCTTATGGACAAAATGAGGTGGTTTCTATTGATAAGCAAGAAATTAATACTCAGGTTTTTGCCAAAGATG
GGGAAACCATTGTGCTTGGCGGCGTATTTCACGACACAATCACGAAAAGCGAAGATAAAGTGCCATTGCTTGGCGATATA
CCCGTTATTAAACGATTATTTAGCAAAGAAAGTGAACGACATCAAAAACGTGAGCTCGTGATTTTCGTGACGCCACATAT
TTTAAAAGCAGGAGAAACGTTAGAGGCGTTGAAACAAAAAAGTGCGGGCAAAAAGTTACAATGA

Domains

Predicted by InterproScan.

Bacterial type II/III secretion system short domain (Secretin_N)

(123-187)

Bacterial type II and III secretion system protein (Secretin)

(269-429)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comE Haemophilus influenzae 86-028NP

97.303

99.553

0.969
  comE Haemophilus influenzae Rd KW20

96.18

99.553

0.957
  comE Glaesserella parasuis strain SC1401

52

95.078

0.494
  pilQ Vibrio campbellii strain DS40M4

42.721

93.736

0.4
  pilQ Vibrio cholerae O1 biovar El Tor strain E7946

42.233

92.17

0.389
  pilQ Vibrio cholerae strain A1552

42.233

92.17

0.389

Multiple sequence alignment