Detailed information    

insolico Bioinformatically predicted

Overview

Name   sigH   Type   Regulator
Locus tag   NMJ60_RS02805 Genome accession   NZ_CP101314
Coordinates   594094..594663 (+) Length   189 a.a.
NCBI ID   WP_000872882.1    Uniprot ID   A0A7U7EXA1
Organism   Staphylococcus aureus strain #492     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 589094..599663
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NMJ60_RS02780 cysE 590307..590954 (+) 648 WP_001805237.1 serine O-acetyltransferase -
  NMJ60_RS02785 cysS 590938..592338 (+) 1401 WP_000631969.1 cysteine--tRNA ligase -
  NMJ60_RS02790 - 592331..592735 (+) 405 WP_000370182.1 Mini-ribonuclease 3 -
  NMJ60_RS02795 rlmB 592743..593489 (+) 747 WP_000390332.1 23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB -
  NMJ60_RS02800 - 593489..594013 (+) 525 WP_000664737.1 NYN domain-containing protein -
  NMJ60_RS02805 sigH 594094..594663 (+) 570 WP_000872882.1 sigma-70 family RNA polymerase sigma factor Regulator
  NMJ60_RS02810 rpmG 594778..594921 (+) 144 WP_001788193.1 50S ribosomal protein L33 -
  NMJ60_RS02815 secE 594977..595159 (+) 183 WP_001074473.1 preprotein translocase subunit SecE -
  NMJ60_RS02820 nusG 595172..595720 (+) 549 WP_001288302.1 transcription termination/antitermination protein NusG -
  NMJ60_RS02825 rplK 595901..596323 (+) 423 WP_001085792.1 50S ribosomal protein L11 -
  NMJ60_RS02830 rplA 596531..597223 (+) 693 WP_001074619.1 50S ribosomal protein L1 -
  NMJ60_RS02835 rplJ 597495..597995 (+) 501 WP_001273085.1 50S ribosomal protein L10 -
  NMJ60_RS02840 rplL 598038..598406 (+) 369 WP_001273586.1 50S ribosomal protein L7/L12 -
  NMJ60_RS02845 - 598581..599189 (+) 609 WP_000020304.1 class I SAM-dependent methyltransferase -

Sequence

Protein


Download         Length: 189 a.a.        Molecular weight: 23044.91 Da        Isoelectric Point: 9.4170

>NTDB_id=709624 NMJ60_RS02805 WP_000872882.1 594094..594663(+) (sigH) [Staphylococcus aureus strain #492]
MKYDLTTQDSTIKRNNSINDKDFEKLVMDLQPLIIRRIKTFGFNHYDLEDLYQEILIRMYRSVQTFDFSGEQPFTNYVQC
LITSVKYDYLRKYLATNKRMDNLINEYRVTYPCAIKRFDVENNYLNKLAIKELICQFKYLSAFEKDVMYLMCEQYKPREI
AQLMHVKEKVIYNAIQRCKNKIKRYFKMI

Nucleotide


Download         Length: 570 bp        

>NTDB_id=709624 NMJ60_RS02805 WP_000872882.1 594094..594663(+) (sigH) [Staphylococcus aureus strain #492]
TTGAAATATGATTTGACAACTCAAGACAGTACAATCAAACGTAACAATTCAATAAATGATAAAGACTTCGAAAAGTTAGT
AATGGATCTACAACCATTAATTATTCGACGCATCAAAACATTTGGATTTAATCATTATGATTTAGAAGACTTATATCAAG
AAATACTTATACGGATGTATAGGTCGGTCCAAACATTTGATTTTAGTGGAGAGCAGCCTTTCACAAATTATGTTCAATGT
TTAATTACGTCTGTAAAGTATGATTATTTGAGAAAATATTTAGCTACAAATAAAAGAATGGATAATTTGATTAATGAATA
TAGAGTTACGTATCCATGTGCAATAAAGCGTTTTGATGTTGAAAACAATTATTTGAATAAATTAGCAATTAAAGAGTTGA
TTTGTCAGTTTAAGTATTTGAGTGCATTTGAAAAAGATGTCATGTATTTAATGTGTGAACAATATAAGCCGAGAGAAATT
GCTCAATTGATGCATGTAAAAGAGAAAGTGATTTATAATGCCATACAACGATGTAAAAATAAAATAAAACGTTATTTCAA
AATGATTTGA

Domains

Predicted by InterproScan.

Sigma-70 region 2 (Sigma70_r2)

(26-92)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7U7EXA1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  sigH Staphylococcus aureus N315

100

100

1
  sigH Staphylococcus aureus MW2

97.884

100

0.979