Detailed information    

insolico Bioinformatically predicted

Overview

Name   comB   Type   Machinery gene
Locus tag   K6J66_RS02885 Genome accession   NZ_AP018771
Coordinates   583465..583971 (+) Length   168 a.a.
NCBI ID   WP_038439363.1    Uniprot ID   -
Organism   Haemophilus influenzae strain CHBN-II-8 isolate 10H27     
Function   type IV pilus biogenesis and function (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 578465..588971
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  K6J66_RS02865 (CHBNII8_05420) - 578570..578899 (-) 330 WP_005629464.1 YbaB/EbfC family nucleoid-associated protein -
  K6J66_RS02870 (CHBNII8_05430) - 579052..579897 (-) 846 WP_038439368.1 23S rRNA (adenine(2030)-N(6))-methyltransferase RlmJ -
  K6J66_RS02875 (CHBNII8_05440) - 579974..582568 (-) 2595 WP_038439366.1 penicillin-binding protein 1A -
  K6J66_RS02880 (CHBNII8_05450) comA 582667..583464 (+) 798 WP_038439365.1 pilus assembly protein PilM Machinery gene
  K6J66_RS02885 (CHBNII8_05460) comB 583465..583971 (+) 507 WP_038439363.1 competence protein ComB Machinery gene
  K6J66_RS02890 (CHBNII8_05470) comC 583968..584489 (+) 522 WP_005662592.1 competence protein ComC Machinery gene
  K6J66_RS02895 (CHBNII8_05480) comD 584486..584899 (+) 414 WP_032823984.1 pilus assembly protein PilP Machinery gene
  K6J66_RS02900 (CHBNII8_05490) comE 584909..586252 (+) 1344 WP_038439361.1 type IV pilus secretin PilQ family protein Machinery gene
  K6J66_RS02905 (CHBNII8_05500) - 586249..586473 (+) 225 Protein_554 transposase -
  K6J66_RS02910 (CHBNII8_05510) - 586605..587291 (+) 687 WP_038439360.1 ComF family protein -
  K6J66_RS02915 (CHBNII8_05520) nfuA 587367..587963 (+) 597 WP_038439359.1 Fe-S biogenesis protein NfuA -
  K6J66_RS02920 (CHBNII8_05530) nudC 588030..588824 (+) 795 WP_038439358.1 NAD(+) diphosphatase -

Sequence

Protein


Download         Length: 168 a.a.        Molecular weight: 19793.72 Da        Isoelectric Point: 9.4939

>NTDB_id=70962 K6J66_RS02885 WP_038439363.1 583465..583971(+) (comB) [Haemophilus influenzae strain CHBN-II-8 isolate 10H27]
MSMNLLPWRTYQHQKRLRRLAFYIALFILLAINLMLAFSNLIEQQKQNLQAQQKSFEQLNQQLHKTTMQIDQLRRAVKVG
EVLTSIPNEQVKKSLQQLSELPFQQGELNKFKQDANNLSLEGNAQDQTEFELIHQFLKKHFPNVKLSQVQPEQDTLFFHF
DVEQGAEK

Nucleotide


Download         Length: 507 bp        

>NTDB_id=70962 K6J66_RS02885 WP_038439363.1 583465..583971(+) (comB) [Haemophilus influenzae strain CHBN-II-8 isolate 10H27]
ATGTCGATGAATTTATTGCCTTGGCGTACTTATCAACATCAAAAGCGTTTACGTCGTTTAGCTTTTTATATCGCTTTATT
TATCTTGCTTGCTATTAATTTAATGTTGGCTTTTAGCAATTTGATTGAACAACAGAAACAAAATTTGCAGGCACAGCAAA
AGTCGTTTGAACAACTTAATCAACAGCTTCATAAAACTACCATGCAAATTGATCAGTTACGCAGAGCGGTGAAAGTTGGT
GAAGTTTTGACATCTATTCCCAACGAGCAAGTAAAAAAGAGTTTACAACAGCTAAGTGAATTACCTTTTCAACAAGGAGA
ACTGAATAAATTTAAACAAGATGCGAATAACTTAAGCTTGGAAGGTAACGCACAAGATCAAACAGAATTTGAACTGATTC
ATCAATTTTTAAAGAAACATTTTCCCAATGTGAAATTAAGTCAGGTTCAACCTGAACAAGATACATTGTTTTTTCACTTT
GATGTGGAACAAGGGGCGGAAAAATGA

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comB Haemophilus influenzae Rd KW20

99.405

100

0.994
  comB Haemophilus influenzae 86-028NP

98.81

100

0.988

Multiple sequence alignment