Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   PHA52_RS12270 Genome accession   NZ_CP116237
Coordinates   2588489..2589133 (+) Length   214 a.a.
NCBI ID   WP_003090351.1    Uniprot ID   A0A0H2ZC55
Organism   Pseudomonas aeruginosa strain MPAO1     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2583489..2594133
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  PHA52_RS12255 (PHA52_12255) - 2584124..2585338 (+) 1215 WP_003113355.1 MFS transporter -
  PHA52_RS12260 (PHA52_12260) - 2585354..2586382 (-) 1029 WP_003097554.1 AraC family transcriptional regulator -
  PHA52_RS12265 (PHA52_12265) pqsH 2587000..2588148 (+) 1149 WP_003090354.1 2-heptyl-3-hydroxy-4(1H)-quinolone synthase -
  PHA52_RS12270 (PHA52_12270) letA 2588489..2589133 (+) 645 WP_003090351.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  PHA52_RS12275 (PHA52_12275) uvrC 2589134..2590960 (+) 1827 WP_003113354.1 excinuclease ABC subunit UvrC -
  PHA52_RS12280 (PHA52_12280) pgsA 2590994..2591554 (+) 561 WP_003090349.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -

Sequence

Protein


Download         Length: 214 a.a.        Molecular weight: 23608.53 Da        Isoelectric Point: 6.1073

>NTDB_id=709280 PHA52_RS12270 WP_003090351.1 2588489..2589133(+) (letA) [Pseudomonas aeruginosa strain MPAO1]
MIKVLVVDDHDLVRTGITRMLADIEGLQVVGQADCGEDCLKLARELKPDVVLMDVKMPGIGGLEATRKLLRSQPDIKVVV
VTVCEEDPFPTRLMQAGAAGYMTKGAGLEEMVQAIRQVFAGQRYISPQIAQQLALKSFQPQQHDSPFDSLSEREIQIALM
IANCHKVQSISDKLCLSPKTVNTYRYRIFEKLSITSDVELALLAVRHGMVDAAS

Nucleotide


Download         Length: 645 bp        

>NTDB_id=709280 PHA52_RS12270 WP_003090351.1 2588489..2589133(+) (letA) [Pseudomonas aeruginosa strain MPAO1]
GTGATTAAGGTGCTGGTGGTCGACGACCACGATCTGGTACGCACCGGTATTACCCGCATGCTGGCCGACATCGAAGGCTT
GCAAGTGGTCGGCCAGGCCGACTGCGGTGAAGACTGTCTGAAACTGGCCCGCGAACTGAAGCCGGATGTCGTCCTGATGG
ACGTGAAGATGCCCGGTATCGGCGGCCTGGAGGCGACCCGCAAGCTGCTGCGCAGCCAGCCCGACATCAAGGTCGTGGTA
GTCACCGTCTGCGAAGAGGATCCGTTCCCCACCCGCCTCATGCAGGCCGGCGCCGCCGGCTACATGACCAAGGGCGCGGG
GCTGGAGGAAATGGTCCAGGCGATTCGCCAGGTCTTCGCCGGCCAGCGCTATATCAGCCCGCAGATCGCCCAGCAACTGG
CGCTGAAGTCCTTCCAGCCGCAGCAGCACGATTCCCCCTTCGATTCGCTGTCCGAGCGCGAGATCCAGATCGCCCTGATG
ATCGCCAACTGCCACAAGGTGCAGAGCATCTCCGACAAGCTGTGCCTGTCGCCGAAGACCGTGAATACCTATCGCTACCG
CATCTTCGAGAAGCTCTCGATCACCAGCGACGTGGAACTGGCGCTGCTCGCCGTCCGCCACGGCATGGTCGATGCCGCCA
GCTAG

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(148-204)

Response regulator receiver domain (Response_reg)

(4-116)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0H2ZC55

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

54.502

98.598

0.537
  letA Legionella pneumophila strain ERS1305867

54.502

98.598

0.537