Detailed information NTG0708985

Bioinformatically predicted

Overview

• Name: comEC
• Type: Machinery gene
• Locus tag: NL113_RS18165
• Genome accession: NZ_CP101130
• Coordinates: 3636631..3638961 (+)
• Length: 776 a.a.
• NCBI ID: WP_006637630.1
• Uniprot ID: M5P6B2
• Organism: Bacillus sp. KRF7
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Genomic Context

Location: 3631631..3643961

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
NL113_RS18125	yhbY	3631835..3632125 (+)	291	WP_006637638.1	ribosome assembly RNA-binding protein YhbY	-
NL113_RS18130	-	3632144..3632713 (+)	570	WP_006637637.1	nicotinate-nucleotide adenylyltransferase	-
NL113_RS18135	yqeK	3632703..3633266 (+)	564	WP_006637636.1	bis(5'-nucleosyl)-tetraphosphatase (symmetrical) YqeK	-
NL113_RS18140	rsfS	3633280..3633633 (+)	354	WP_006637635.1	ribosome silencing factor	-
NL113_RS18145	-	3633633..3634388 (+)	756	WP_006637634.1	class I SAM-dependent methyltransferase	-
NL113_RS18150	comER	3634456..3635277 (-)	822	WP_006637633.1	late competence protein ComER	-
NL113_RS18155	comEA	3635361..3635987 (+)	627	WP_040348230.1	helix-hairpin-helix domain-containing protein	Machinery gene
NL113_RS18160	-	3636055..3636624 (+)	570	WP_006637631.1	ComE operon protein 2	-
NL113_RS18165	comEC	3636631..3638961 (+)	2331	WP_006637630.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
NL113_RS18170	-	3639052..3639183 (-)	132	WP_006637629.1	YqzM family protein	-
NL113_RS18175	holA	3639416..3640456 (+)	1041	WP_006637628.1	DNA polymerase III subunit delta	-
NL113_RS18180	rpsT	3640504..3640770 (-)	267	WP_006637627.1	30S ribosomal protein S20	-
NL113_RS18185	gpr	3640976..3642082 (+)	1107	WP_006637626.1	GPR endopeptidase	-
NL113_RS18190	spoIIP	3642217..3643419 (+)	1203	WP_006637625.1	stage II sporulation protein P	-
NL113_RS18195	-	3643437..3643760 (+)	324	WP_006637624.1	YqxA family protein	-

Sequence

Protein

• Length: 776 a.a.
• Molecular weight: 85558.84 Da
• Isoelectric Point: 9.5265

>NTDB_id=708985 NL113_RS18165 WP_006637630.1 3636631..3638961(+) (comEC) [Bacillus sp. KRF7]
MGLLYRILPCGAISAAAGIASAQSSSFLPLIIFLSLLFIFSQIKKQFLLFFICTVICGFYMIYFMAIDSSNTTRYKEGAF
RAYMSVRDIPRIDGDRLAFTAEMAEGEAVKANYILQSPQEKAALSKLEPGSTCFMTGVLKTPKRATVPGTFDRKEYLRQQ
GIHWNFAVQSIKGCQSGGGPASFLLKIRKAGLGFIEKHVPETSAGIVQALVFGDRFLIEQDVLDGYQSLGIIHLLAISGL
HVGILSAVLFYMLLRIGITREHAKWCLIMMLPAAVMLTGAAPSVLRAAFMSEIYLLSSLFKNRLRGAQVLSIAWLGLLLF
NPYMLFQAGFQLSFAASFVFILSKEILLKPKHQTVRLLLASFVAQLGSLPILLFHFQEVSFLSVLMNLCFVPFYVFIVMP
LSFGGLLILLVAPPLGNLAMGVLDWLLGWSHWAVKAASSLEIFTFSAVKPDVIHLLFYIASICVLLMSIEKAISCKTLAI
PACLLASAFLFHAAAPHFIGSGEVTMLDVGQGDSIYISAPGQKGNVLIDTGGIVSFKKEAWRERKKDVSLGERVLIPFLA
SKGVKQLDALILTHADHDHMGEAEILIGKNKVKQLIVPKGYAAEPADEKLLRFALERGVDVKTAKRGDRLVIGDLVFYVL
SPETADKNSKNNSSLVLWMNAGGFSWLLTGDLEKEGEREMLKAYPRLKADILKVGHHGSKGSTGEELINRIEPKAALISA
GENNRYRHPHKEVLEILKRHQVKVFRTDRDGAVQYLFGRGDGTFLLHPPYDKVYSP

Nucleotide

• Length: 2331 bp

>NTDB_id=708985 NL113_RS18165 WP_006637630.1 3636631..3638961(+) (comEC) [Bacillus sp. KRF7]
ATGGGTCTTCTCTACCGCATCCTTCCCTGCGGAGCAATTTCAGCAGCAGCCGGAATTGCTTCCGCCCAATCTTCTTCTTT
TCTCCCCCTCATCATCTTTTTAAGTCTGCTTTTCATCTTCAGTCAGATCAAGAAGCAATTTCTCCTTTTTTTCATTTGTA
CAGTCATCTGCGGTTTTTATATGATTTATTTTATGGCCATTGACAGTTCGAATACGACTCGCTACAAGGAAGGCGCTTTC
CGTGCGTACATGTCTGTTCGCGATATTCCGAGAATAGACGGGGACCGTCTCGCTTTCACTGCCGAAATGGCTGAAGGAGA
AGCGGTGAAAGCGAACTACATCCTTCAGTCTCCACAGGAAAAAGCGGCGCTTTCGAAGCTTGAGCCGGGCAGTACATGTT
TCATGACAGGCGTATTAAAAACTCCTAAGAGAGCAACTGTACCCGGGACGTTTGATCGTAAAGAATATCTGCGCCAGCAG
GGCATTCACTGGAATTTTGCGGTTCAGTCGATCAAAGGCTGTCAGTCAGGAGGCGGTCCGGCTTCATTTTTGCTGAAAAT
CCGAAAAGCCGGTCTTGGTTTTATAGAGAAACATGTGCCTGAAACATCTGCGGGTATTGTACAGGCGCTGGTTTTCGGCG
ACAGGTTTCTGATTGAGCAGGACGTGCTGGACGGATATCAAAGCCTCGGGATCATCCATCTTCTAGCCATTTCAGGTCTC
CATGTAGGCATACTTTCGGCCGTTTTATTTTACATGCTGCTCCGGATCGGGATAACGAGGGAACATGCAAAATGGTGCTT
GATCATGATGCTTCCAGCCGCGGTTATGCTGACAGGCGCAGCTCCCTCGGTGCTTAGAGCGGCGTTCATGTCTGAAATAT
ATTTGCTTTCTTCATTGTTCAAGAATCGTTTAAGAGGCGCGCAGGTTCTCAGCATTGCCTGGCTCGGTCTATTGTTATTC
AACCCCTATATGCTTTTCCAGGCAGGTTTTCAGCTTTCTTTTGCAGCATCCTTCGTGTTTATTCTTTCAAAAGAAATACT
TTTAAAACCTAAACATCAAACCGTCAGGCTGCTGTTGGCTTCTTTTGTGGCCCAGCTCGGTTCACTTCCGATTCTTCTCT
TTCACTTTCAAGAGGTTTCCTTCCTCAGTGTCCTCATGAATCTATGTTTTGTACCGTTTTATGTGTTCATCGTGATGCCG
CTGTCATTTGGCGGGTTATTGATTTTGTTGGTTGCGCCTCCTCTTGGGAATCTTGCAATGGGCGTGCTTGACTGGCTGCT
CGGATGGAGCCATTGGGCGGTAAAAGCGGCGTCTTCCCTTGAGATCTTCACGTTCTCCGCTGTTAAACCCGATGTCATCC
ATTTGCTTTTTTATATAGCTTCAATATGTGTCCTTCTGATGTCTATCGAAAAAGCAATCTCTTGCAAAACGCTCGCCATT
CCGGCTTGTCTGCTTGCTTCCGCTTTTCTGTTTCACGCCGCTGCCCCGCATTTCATCGGTTCAGGAGAAGTGACAATGCT
TGATGTCGGGCAGGGAGACAGCATATATATCAGCGCTCCGGGGCAAAAGGGAAATGTTTTAATTGATACCGGAGGGATTG
TTTCCTTTAAAAAGGAGGCATGGCGGGAAAGAAAAAAAGATGTATCCTTGGGAGAAAGAGTATTAATCCCCTTTCTTGCT
TCAAAAGGCGTTAAACAACTTGATGCTTTGATTTTGACGCATGCCGATCATGATCATATGGGAGAGGCTGAAATTCTGAT
CGGGAAAAATAAGGTGAAACAATTGATTGTGCCGAAAGGATATGCGGCAGAACCGGCAGATGAAAAGCTCCTCCGTTTTG
CTCTGGAAAGGGGAGTGGATGTGAAAACGGCAAAGAGAGGGGACCGCTTGGTCATTGGTGATCTGGTGTTTTATGTTCTT
TCGCCGGAAACGGCAGACAAAAACAGCAAAAACAACAGTTCCCTCGTTTTATGGATGAACGCTGGAGGCTTCAGCTGGCT
TTTAACAGGCGATTTGGAAAAGGAAGGCGAGCGGGAGATGCTCAAAGCCTATCCAAGGCTGAAAGCCGACATTCTTAAAG
TCGGCCACCATGGGAGCAAAGGATCGACAGGAGAGGAGCTGATCAACCGTATCGAACCGAAAGCGGCCCTCATATCGGCG
GGGGAAAACAATCGCTACCGCCATCCCCACAAAGAGGTGCTGGAGATTTTAAAACGCCATCAGGTCAAGGTGTTCAGGAC
AGACCGGGACGGAGCGGTTCAGTACCTATTTGGAAGAGGGGACGGAACGTTTTTGCTCCATCCTCCATATGATAAAGTAT
ATTCCCCGTAA

Domains

Predicted by InterproScan.

• Metallo-beta-lactamase superfamily (Lactamase_B) (508-721)

• Competence protein (Competence) (210-470)

• Domain of unknown function (DUF4131) (DUF4131) (28-171)

3D structure

• AlphaFold DB: M5P6B2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEC	Bacillus subtilis subsp. subtilis str. 168	49.347	98.711	0.487