Detailed information    

insolico Bioinformatically predicted

Overview

Name   dprA   Type   Machinery gene
Locus tag   NMK49_RS05710 Genome accession   NZ_CP101124
Coordinates   1180407..1181279 (+) Length   290 a.a.
NCBI ID   WP_000593192.1    Uniprot ID   A0A140HKN1
Organism   Staphylococcus aureus subsp. aureus RN4220     
Function   ssDNA binding; loading RecA onto ssDNA (predicted from homology)   
DNA processing

Genomic Context

Location: 1175407..1186279
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NMK49_RS05690 sucC 1175521..1176687 (+) 1167 WP_001020801.1 ADP-forming succinate--CoA ligase subunit beta -
  NMK49_RS05695 sucD 1176709..1177617 (+) 909 WP_000110253.1 succinate--CoA ligase subunit alpha -
  NMK49_RS05700 - 1177844..1178962 (+) 1119 WP_001041662.1 LysM peptidoglycan-binding domain-containing protein -
  NMK49_RS05705 fmhC 1178990..1180234 (+) 1245 WP_000672867.1 FemA/FemB family glycyltransferase FmhC -
  NMK49_RS05710 dprA 1180407..1181279 (+) 873 WP_000593192.1 DNA-processing protein DprA Machinery gene
  NMK49_RS05715 topA 1181453..1183528 (+) 2076 WP_001548566.1 type I DNA topoisomerase -
  NMK49_RS05720 trmFO 1183684..1184991 (+) 1308 WP_000195254.1 methylenetetrahydrofolate--tRNA-(uracil(54)- C(5))-methyltransferase (FADH(2)-oxidizing) TrmFO -

Sequence

Protein


Download         Length: 290 a.a.        Molecular weight: 33564.99 Da        Isoelectric Point: 9.5094

>NTDB_id=708865 NMK49_RS05710 WP_000593192.1 1180407..1181279(+) (dprA) [Staphylococcus aureus subsp. aureus RN4220]
MIKLFLLKLYWAHFSTKQIHQFLMAYPNVIKEEGRKKDSYLCEWVNREENVHLLRKYYAFIKLDHNDIIKELQKLKVSYI
TYMDSEYPVLLKEIYQFPLLLFYKGNIKLINNMHHLAVVGARDSTSYTQQSLEFLLSNDKSKYLTIVSGLAQGADAMAHQ
IALKYNLPTIAVLAFGHQTHYPKSTLALRNKIEEKGLVISEYPPHTPIAKYRFPERNRIISGLSKGVLITEAKEQSGSHI
TIDFALEQNRNVYVLPGSMFNPMTKGNLLRIQEGAKVVLNANDIFEDYYI

Nucleotide


Download         Length: 873 bp        

>NTDB_id=708865 NMK49_RS05710 WP_000593192.1 1180407..1181279(+) (dprA) [Staphylococcus aureus subsp. aureus RN4220]
TTGATTAAACTATTTTTGCTTAAGTTATACTGGGCACACTTTTCGACTAAACAAATTCATCAATTTTTAATGGCATATCC
TAATGTAATTAAAGAGGAGGGAAGAAAAAAAGATAGTTATTTATGTGAATGGGTGAATAGGGAAGAAAATGTTCATTTAT
TACGTAAATACTATGCTTTTATAAAACTTGATCATAACGATATTATTAAAGAACTGCAGAAATTAAAAGTAAGTTACATT
ACATATATGGATTCTGAATACCCAGTGCTATTAAAAGAAATATATCAATTTCCATTACTTCTTTTCTATAAAGGGAACAT
CAAATTAATAAATAATATGCATCATTTGGCAGTAGTAGGTGCAAGAGATTCTACAAGTTATACCCAACAGTCTTTAGAAT
TTTTATTATCAAATGATAAAAGCAAATATTTAACAATTGTTTCCGGCCTTGCTCAAGGAGCTGATGCAATGGCACATCAA
ATAGCTTTAAAATACAATCTCCCTACAATTGCAGTTTTAGCCTTTGGCCATCAAACACATTATCCCAAAAGTACATTAGC
ATTAAGAAATAAAATAGAAGAAAAAGGTTTAGTTATATCTGAATATCCACCACATACACCAATCGCTAAATATAGATTTC
CTGAGCGCAATAGAATTATCAGCGGTTTGTCAAAAGGGGTTTTAATTACTGAGGCTAAGGAACAAAGTGGCAGTCACATC
ACGATAGATTTTGCATTAGAGCAAAATAGAAATGTTTATGTTTTACCTGGATCTATGTTTAATCCTATGACAAAAGGTAA
TTTATTACGTATCCAAGAAGGTGCTAAGGTAGTATTAAACGCTAATGATATATTTGAAGACTACTATATTTAA

Domains

Predicted by InterproScan.

DNA recombination-mediator protein A (DNA_processg_A)

(72-279)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A140HKN1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  dprA Staphylococcus aureus MW2

100

100

1
  dprA Staphylococcus aureus N315

99.655

100

0.997