Detailed information    

insolico Bioinformatically predicted

Overview

Name   sigH   Type   Regulator
Locus tag   NMK49_RS02480 Genome accession   NZ_CP101124
Coordinates   526687..527256 (+) Length   189 a.a.
NCBI ID   WP_000872873.1    Uniprot ID   -
Organism   Staphylococcus aureus subsp. aureus RN4220     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 521687..532256
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NMK49_RS02455 cysE 522900..523547 (+) 648 WP_001805237.1 serine O-acetyltransferase -
  NMK49_RS02460 cysS 523531..524931 (+) 1401 WP_000631963.1 cysteine--tRNA ligase -
  NMK49_RS02465 - 524924..525328 (+) 405 WP_000370182.1 Mini-ribonuclease 3 -
  NMK49_RS02470 rlmB 525336..526082 (+) 747 WP_000390328.1 23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB -
  NMK49_RS02475 - 526082..526606 (+) 525 WP_000664738.1 NYN domain-containing protein -
  NMK49_RS02480 sigH 526687..527256 (+) 570 WP_000872873.1 sigma-70 family RNA polymerase sigma factor Regulator
  NMK49_RS02485 rpmG 527371..527514 (+) 144 WP_001788193.1 50S ribosomal protein L33 -
  NMK49_RS02490 secE 527570..527752 (+) 183 WP_001074473.1 preprotein translocase subunit SecE -
  NMK49_RS02495 nusG 527765..528313 (+) 549 WP_001288302.1 transcription termination/antitermination protein NusG -
  NMK49_RS02500 rplK 528494..528916 (+) 423 WP_001085792.1 50S ribosomal protein L11 -
  NMK49_RS02505 rplA 529124..529816 (+) 693 WP_001074619.1 50S ribosomal protein L1 -
  NMK49_RS02510 rplJ 530088..530588 (+) 501 WP_001273085.1 50S ribosomal protein L10 -
  NMK49_RS02515 rplL 530631..530999 (+) 369 WP_001273586.1 50S ribosomal protein L7/L12 -
  NMK49_RS02520 - 531174..531782 (+) 609 WP_000020304.1 class I SAM-dependent methyltransferase -

Sequence

Protein


Download         Length: 189 a.a.        Molecular weight: 23028.91 Da        Isoelectric Point: 9.4170

>NTDB_id=708858 NMK49_RS02480 WP_000872873.1 526687..527256(+) (sigH) [Staphylococcus aureus subsp. aureus RN4220]
MKYDLTTQDSTIKRNNAINDKDFEKLVMDLQPLIIRRIKTFGFNHYDLEDLYQEILIRMYRSVQTFDFSGEQPFTNYVQC
LITSVKYDYLRKYLATNKRMDNLINEYRVTYPCAIKRFDVENNYLNKLAIKELICQFKYLSAFEKDVMYLMCEQYKPREI
AQLMHVKEKVIYNAIQRCKNKIKRYFKMI

Nucleotide


Download         Length: 570 bp        

>NTDB_id=708858 NMK49_RS02480 WP_000872873.1 526687..527256(+) (sigH) [Staphylococcus aureus subsp. aureus RN4220]
TTGAAATACGATTTGACAACTCAAGACAGTACAATCAAACGTAACAATGCAATAAATGATAAAGACTTCGAAAAGTTAGT
AATGGATCTACAACCATTAATTATTCGACGCATCAAAACATTTGGATTTAATCATTATGATTTAGAAGACTTATATCAAG
AAATACTTATACGGATGTATAGGTCGGTCCAAACATTTGATTTTAGTGGAGAGCAGCCTTTCACAAATTATGTTCAATGT
TTAATTACGTCTGTAAAGTATGATTATTTGAGAAAATATTTAGCTACAAATAAAAGAATGGATAATTTGATTAATGAATA
TAGAGTTACGTATCCATGTGCAATAAAGCGTTTTGATGTTGAAAACAATTATTTGAATAAATTAGCAATTAAAGAGTTGA
TTTGTCAGTTTAAGTATTTGAGTGCATTTGAAAAAGATGTCATGTATTTAATGTGTGAACAATATAAGCCGAGAGAAATT
GCTCAATTGATGCATGTAAAAGAGAAAGTGATTTATAATGCCATACAACGATGTAAAAATAAAATAAAACGTTATTTCAA
AATGATTTGA

Domains

Predicted by InterproScan.

Sigma-70 region 2 (Sigma70_r2)

(26-92)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  sigH Staphylococcus aureus N315

99.471

100

0.995
  sigH Staphylococcus aureus MW2

98.413

100

0.984