Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEA   Type   Machinery gene
Locus tag   NLA26_RS05555 Genome accession   NZ_CP101123
Coordinates   1075026..1075712 (-) Length   228 a.a.
NCBI ID   WP_001794049.1    Uniprot ID   A0A0E1X4U4
Organism   Staphylococcus aureus strain MN8     
Function   dsDNA binding to the cell surface (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1070026..1080712
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NLA26_RS05535 rpsT 1070940..1071191 (+) 252 WP_001274017.1 30S ribosomal protein S20 -
  NLA26_RS05540 holA 1071236..1072210 (-) 975 WP_001282570.1 DNA polymerase III subunit delta -
  NLA26_RS05545 comEC 1072267..1074468 (-) 2202 WP_001794051.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  NLA26_RS05550 - 1074473..1074934 (-) 462 WP_000439692.1 ComE operon protein 2 -
  NLA26_RS05555 comEA 1075026..1075712 (-) 687 WP_001794049.1 ComEA family DNA-binding protein Machinery gene
  NLA26_RS05560 - 1075752..1076468 (-) 717 WP_000084835.1 class I SAM-dependent methyltransferase -
  NLA26_RS05565 rsfS 1076471..1076824 (-) 354 WP_001088020.1 ribosome silencing factor -
  NLA26_RS05570 yqeK 1076825..1077409 (-) 585 WP_001019324.1 bis(5'-nucleosyl)-tetraphosphatase (symmetrical) YqeK -
  NLA26_RS05575 nadD 1077399..1077968 (-) 570 WP_000822938.1 nicotinate (nicotinamide) nucleotide adenylyltransferase -
  NLA26_RS05580 yhbY 1077971..1078261 (-) 291 WP_000955232.1 ribosome assembly RNA-binding protein YhbY -
  NLA26_RS05585 aroE 1078265..1079071 (-) 807 WP_000666750.1 shikimate dehydrogenase -
  NLA26_RS05590 yqeH 1079085..1080185 (-) 1101 WP_001280134.1 ribosome biogenesis GTPase YqeH -

Sequence

Protein


Download         Length: 228 a.a.        Molecular weight: 25766.38 Da        Isoelectric Point: 9.3383

>NTDB_id=708831 NLA26_RS05555 WP_001794049.1 1075026..1075712(-) (comEA) [Staphylococcus aureus strain MN8]
MVLLYQFLLRYKDFLAQWKLYIISAVVLIMVLIGFIFWRQDDYTSRDFENKDTVLKQSTSENSSLSKLEDVQVKDGDNSK
NKGPVYVDIKGAVKHPNVYKMTSKDRVVDLLDKAQLLDDADVSQINLSEKLTDQKMIFIPHKGQKNVEPQFGANSVHVKN
GNTNNTKVNLNTASVSELMSVPGVGQAKANAIVEYRNQQGAFQEIDDLKKVKGFGSKTFDKLNSYFTT

Nucleotide


Download         Length: 687 bp        

>NTDB_id=708831 NLA26_RS05555 WP_001794049.1 1075026..1075712(-) (comEA) [Staphylococcus aureus strain MN8]
GTGGTTTTATTGTATCAATTTTTATTACGCTATAAAGATTTTTTAGCTCAATGGAAGTTATATATTATAAGTGCTGTTGT
TTTAATTATGGTATTAATTGGTTTTATATTCTGGAGACAAGATGATTATACTTCAAGAGATTTTGAAAATAAAGATACTG
TTCTGAAACAAAGCACTAGTGAAAATAGTAGTTTGTCCAAATTAGAAGATGTCCAGGTCAAAGATGGAGATAATTCCAAA
AATAAAGGTCCTGTATATGTCGATATAAAAGGTGCTGTTAAACATCCTAATGTTTATAAAATGACATCTAAGGATAGAGT
AGTTGATTTACTTGATAAAGCACAATTATTAGATGATGCAGATGTAAGTCAAATTAATTTGTCTGAAAAATTAACAGATC
AAAAAATGATTTTCATTCCTCATAAAGGACAAAAGAATGTTGAACCACAATTTGGAGCAAACAGTGTGCACGTAAAAAAT
GGGAACACAAATAATACTAAAGTAAATTTAAATACGGCATCTGTATCAGAATTGATGTCTGTTCCTGGAGTAGGGCAAGC
TAAAGCTAATGCAATTGTTGAATATCGCAACCAACAAGGTGCATTTCAAGAAATTGACGATTTGAAAAAAGTAAAAGGTT
TTGGAAGTAAAACTTTTGATAAACTGAATTCTTATTTCACGACATAA

Domains

Predicted by InterproScan.

Helix-hairpin-helix motif (HHH_3)

(164-227)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0E1X4U4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEA Staphylococcus aureus MW2

95.595

99.561

0.952
  comEA Staphylococcus aureus N315

95.595

99.561

0.952