Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   PIC86_RS09360 Genome accession   NZ_CP116169
Coordinates   1927657..1929489 (+) Length   610 a.a.
NCBI ID   WP_073520308.1    Uniprot ID   -
Organism   Escherichia coli strain DETEC-P1056     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1922657..1934489
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  PIC86_RS09325 (PIC86_09325) dcyD 1922883..1923869 (+) 987 WP_001128213.1 D-cysteine desulfhydrase -
  PIC86_RS09330 (PIC86_09330) tcyL 1923884..1924552 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  PIC86_RS09335 (PIC86_09335) tcyN 1924549..1925301 (+) 753 WP_001272994.1 L-cystine ABC transporter ATP-binding protein TcyN -
  PIC86_RS09340 (PIC86_09340) sdiA 1925531..1926253 (+) 723 WP_001154287.1 transcriptional regulator SdiA -
  PIC86_RS09345 (PIC86_09345) yecF 1926321..1926545 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  PIC86_RS09350 (PIC86_09350) yecU 1926532..1926708 (-) 177 WP_000590347.1 protein YecU -
  PIC86_RS24305 - 1926746..1926862 (-) 117 WP_001302039.1 hypothetical protein -
  PIC86_RS09355 (PIC86_09355) letA 1927004..1927660 (+) 657 WP_000611335.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  PIC86_RS09360 (PIC86_09360) uvrC 1927657..1929489 (+) 1833 WP_073520308.1 excinuclease ABC subunit UvrC Machinery gene
  PIC86_RS09365 (PIC86_09365) pgsA 1929546..1930094 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  PIC86_RS09385 (PIC86_09385) yecA 1930744..1931409 (+) 666 WP_000847902.1 UPF0149 family protein YecA -
  PIC86_RS09390 (PIC86_09390) tyrP 1931471..1932682 (-) 1212 WP_000797573.1 tyrosine transporter TyrP -
  PIC86_RS09395 (PIC86_09395) yecH 1932873..1933112 (+) 240 WP_000377225.1 YecH family metal-binding protein -
  PIC86_RS09400 (PIC86_09400) ftnA 1933150..1933647 (-) 498 WP_000917208.1 non-heme ferritin -
  PIC86_RS09405 (PIC86_09405) yecR 1933818..1934141 (-) 324 WP_001237866.1 YecR-like lipofamily protein -

Sequence

Protein


Download         Length: 610 a.a.        Molecular weight: 68202.06 Da        Isoelectric Point: 9.3685

>NTDB_id=708661 PIC86_RS09360 WP_073520308.1 1927657..1929489(+) (uvrC) [Escherichia coli strain DETEC-P1056]
MSDQFDAKAFLKTVTSQPGVYRMYDAGGTVIYIGKAKDLKKRLSSYFRSNLASRKTEALVAQIQQIDVTVTHTETEALLL
EHNYIKLYQPRYNVLLRDDKSYPFIFLSGDTHPRLAMHRGAKHAKGEYFGPFPNGYAVRETLALLQKIFPIRQCENSVYR
NRSRPCLQYQIGRCLGPCVEGLVSEEEYAQQVEYVRLFLSGKDDQVLTQLISRMETASQNLEFEEAARIRDQIQAVRRVT
EKQFVSNTGDDLDVIGVAFDAGMACVHVLFIRQGKVLGSRSYFPKVPGGTELSEVVETFVGQFYLQGSQMRTLPGEILLD
FNLSDKTLLADSLSELAGRKINVQTKPRGDRARYLKLARTNAATALTSKLSQQSTVHQRLTALASVLKLPEVKRMECFDI
SHTMGEQTVASCVVFDANGPLRAEYRRYNITGITPGDDYAAMNQVLRRRYGKAIDDSKIPDVILIDGGKGQLAQAKNVFA
ELDVSWDKNHPLLLGVAKGADRKAGLETLFFEPEGEGFSLPPDSPALHVIQHIRDESHDHAIGGHRKKRAKVKNTSSLET
IEGVGPKRRQMLLKYMGGLQGLRNASVEEIAKVPGISQGLAEKIFWSLKH

Nucleotide


Download         Length: 1833 bp        

>NTDB_id=708661 PIC86_RS09360 WP_073520308.1 1927657..1929489(+) (uvrC) [Escherichia coli strain DETEC-P1056]
GTGAGTGATCAGTTTGACGCAAAAGCGTTTTTAAAAACCGTAACCAGCCAGCCAGGCGTTTATCGCATGTACGATGCTGG
TGGTACGGTTATCTATATCGGCAAAGCGAAAGACCTGAAAAAACGGCTTTCCAGCTATTTCCGTAGCAACCTCGCTTCGC
GCAAAACCGAAGCGCTGGTCGCCCAGATTCAGCAAATTGATGTAACGGTTACTCATACAGAAACCGAAGCGCTGTTGCTG
GAACACAACTACATCAAACTCTATCAGCCGCGTTACAACGTTTTGCTACGCGATGATAAATCTTATCCTTTTATCTTCCT
GAGTGGCGATACCCACCCGCGTCTGGCGATGCATCGTGGTGCGAAGCATGCCAAAGGTGAATATTTCGGCCCGTTCCCGA
ATGGCTATGCCGTACGTGAAACTCTGGCGCTACTGCAAAAGATTTTCCCCATTCGCCAGTGCGAAAATAGTGTTTATCGC
AATCGCTCGCGTCCGTGTCTGCAATATCAGATAGGGCGCTGTCTGGGACCGTGCGTTGAAGGACTGGTGAGTGAAGAAGA
ATACGCTCAGCAGGTCGAGTATGTGCGCCTGTTTTTGTCTGGCAAAGATGATCAGGTGCTTACGCAACTCATTAGCCGTA
TGGAAACTGCCAGTCAGAATCTGGAGTTTGAAGAAGCGGCACGTATTCGCGACCAAATTCAGGCGGTGCGACGCGTCACC
GAAAAACAATTCGTTTCCAATACCGGCGACGACCTTGACGTTATTGGTGTGGCGTTCGATGCGGGCATGGCTTGTGTCCA
CGTATTGTTCATTCGTCAGGGCAAAGTGCTCGGCAGCCGCAGCTATTTCCCGAAAGTGCCTGGCGGTACGGAACTGAGCG
AGGTGGTAGAAACCTTCGTAGGTCAGTTCTATTTACAAGGCAGCCAGATGCGCACCTTACCGGGTGAGATCCTGCTCGAT
TTTAATCTTAGCGATAAAACGCTGCTCGCCGATTCCCTTTCAGAACTGGCGGGACGCAAGATTAATGTTCAAACCAAACC
TCGCGGCGATAGGGCGCGTTATCTGAAACTCGCGCGCACCAATGCGGCGACGGCCTTAACCAGCAAACTTTCGCAGCAAT
CTACCGTTCACCAGCGGCTGACCGCGCTTGCCAGCGTGTTGAAATTGCCGGAAGTGAAGCGGATGGAGTGCTTTGACATC
AGCCATACCATGGGCGAACAAACCGTCGCTTCCTGTGTGGTGTTTGATGCTAACGGCCCGCTGCGTGCGGAGTATCGGCG
CTATAACATTACAGGCATCACGCCGGGCGATGATTATGCGGCGATGAATCAGGTGCTGCGTCGGCGTTATGGTAAAGCCA
TTGACGACAGTAAGATCCCGGATGTGATCCTTATCGACGGCGGCAAAGGCCAGCTTGCGCAGGCGAAAAATGTCTTCGCC
GAACTGGATGTCTCATGGGATAAAAATCATCCGCTGCTACTTGGCGTTGCCAAAGGTGCAGATCGTAAGGCTGGACTGGA
AACGCTGTTCTTTGAGCCGGAAGGTGAGGGATTTAGTTTGCCGCCAGATTCACCCGCGCTGCATGTTATCCAGCATATTC
GCGATGAATCACATGATCACGCGATTGGCGGGCACCGTAAAAAACGGGCGAAAGTCAAAAATACCAGTTCCCTGGAAACC
ATTGAAGGCGTCGGGCCAAAACGTCGGCAAATGTTGTTGAAATATATGGGCGGTTTGCAAGGTTTACGTAACGCCAGCGT
CGAGGAAATTGCAAAAGTGCCGGGTATTTCGCAAGGTCTGGCAGAAAAGATCTTCTGGTCGTTGAAACATTGA

Domains

Predicted by InterProScan.

UvrB/uvrC motif (UVR)

(205-237)

Helix-hairpin-helix domain (HHH_5)

(558-609)

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(385-542)

GIY-YIG catalytic domain (GIY-YIG)

(18-93)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Streptococcus pneumoniae TIGR4

37.727

99.508

0.375
  uvrC Streptococcus pneumoniae R6

37.397

99.508

0.372
  uvrC Streptococcus pneumoniae D39

37.397

99.508

0.372