Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   H7678_RS08235 Genome accession   NZ_AP023393
Coordinates   1670486..1671127 (-) Length   213 a.a.
NCBI ID   WP_014612503.1    Uniprot ID   A0A9X9QU89
Organism   Streptococcus dysgalactiae subsp. equisimilis strain 89     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1665486..1676127
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  H7678_RS08215 (SDSE89_15970) - 1666860..1667498 (+) 639 WP_004230529.1 YigZ family protein -
  H7678_RS08220 (SDSE89_15980) cysK 1667602..1668537 (+) 936 WP_004230536.1 cysteine synthase A -
  H7678_RS08225 (SDSE89_15990) - 1668690..1669049 (-) 360 WP_003056775.1 S1 RNA-binding domain-containing protein -
  H7678_RS08230 (SDSE89_16000) - 1669049..1670449 (-) 1401 WP_184010292.1 bifunctional Cof-type HAD-IIB family hydrolase/peptidylprolyl isomerase -
  H7678_RS08235 (SDSE89_16010) vraR 1670486..1671127 (-) 642 WP_014612503.1 response regulator transcription factor Regulator
  H7678_RS08240 (SDSE89_16020) - 1671120..1672124 (-) 1005 WP_003061197.1 sensor histidine kinase -
  H7678_RS08245 (SDSE89_16030) liaF 1672121..1672813 (-) 693 WP_065355409.1 cell wall-active antibiotics response protein LiaF -
  H7678_RS08250 (SDSE89_16040) pknB 1672940..1674835 (-) 1896 WP_004230538.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  H7678_RS08255 (SDSE89_16050) - 1674832..1675572 (-) 741 WP_014612505.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -

Sequence

Protein


Download         Length: 213 a.a.        Molecular weight: 23806.38 Da        Isoelectric Point: 4.7966

>NTDB_id=70863 H7678_RS08235 WP_014612503.1 1670486..1671127(-) (vraR) [Streptococcus dysgalactiae subsp. equisimilis strain 89]
MSNIRVILVDDHEMVRMGLKSFLNLQPDIDVIGEASNGREGVELALALKPDVLVMDLVMPELGGVEATLEILDKWKDAKV
LVLTSYLDNEKIYPVIDAGAKGYMLKTSSAAEILNAIRKVSKGELAIETEVDKKIKAHDQHPDLHEELTAREYDILHLLA
KGYDNQTIADELFISLKTVKTHVSNILAKLEVDDRTQAVVYAFRHHLVPQDDN

Nucleotide


Download         Length: 642 bp        

>NTDB_id=70863 H7678_RS08235 WP_014612503.1 1670486..1671127(-) (vraR) [Streptococcus dysgalactiae subsp. equisimilis strain 89]
ATGAGTAACATAAGAGTGATACTAGTGGATGATCATGAAATGGTCCGTATGGGACTTAAAAGTTTTTTGAATTTACAACC
AGATATCGACGTTATTGGCGAAGCTTCTAATGGACGTGAGGGAGTTGAGTTGGCCTTAGCCTTAAAACCAGATGTGCTGG
TTATGGATTTGGTGATGCCAGAATTAGGTGGGGTTGAGGCGACTTTGGAAATCCTCGATAAGTGGAAAGATGCCAAAGTA
TTGGTCTTGACCTCTTATTTGGACAATGAGAAAATTTACCCTGTCATTGATGCTGGTGCTAAAGGTTACATGTTAAAGAC
TTCTAGTGCAGCCGAAATTCTAAACGCTATTCGGAAAGTTTCAAAAGGTGAATTGGCCATTGAAACAGAGGTAGACAAAA
AAATTAAAGCGCATGACCAACACCCCGATTTGCATGAAGAGCTAACCGCGCGCGAGTATGATATTTTACATCTTTTAGCT
AAAGGGTATGATAATCAAACTATAGCGGATGAACTTTTCATCTCCTTGAAAACCGTCAAAACACATGTGTCCAATATTCT
AGCCAAGTTAGAAGTTGATGACCGAACTCAAGCTGTTGTATACGCTTTCCGACACCATTTAGTCCCCCAAGATGATAATT
AG

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(6-118)

Bacterial regulatory proteins, luxR family (GerE)

(148-202)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A9X9QU89

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

51.691

97.183

0.502
  degU Bacillus subtilis subsp. subtilis str. 168

35.398

100

0.376

Multiple sequence alignment