Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   PID12_RS09355 Genome accession   NZ_CP116166
Coordinates   1933359..1934015 (+) Length   218 a.a.
NCBI ID   WP_000611335.1    Uniprot ID   Q3Z2T8
Organism   Escherichia coli strain DETEC-P169     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1928359..1939015
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  PID12_RS09325 (PID12_09325) dcyD 1929239..1930225 (+) 987 WP_046659907.1 D-cysteine desulfhydrase -
  PID12_RS09330 (PID12_09330) tcyL 1930240..1930908 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  PID12_RS09335 (PID12_09335) tcyN 1930905..1931657 (+) 753 WP_001272994.1 L-cystine ABC transporter ATP-binding protein TcyN -
  PID12_RS09340 (PID12_09340) sdiA 1931887..1932609 (+) 723 WP_001154276.1 transcriptional regulator SdiA -
  PID12_RS09345 (PID12_09345) yecF 1932676..1932900 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  PID12_RS09350 (PID12_09350) yecU 1932887..1933063 (-) 177 WP_000590347.1 protein YecU -
  PID12_RS24490 - 1933146..1933217 (-) 72 Protein_1829 transcriptional regulator -
  PID12_RS09355 (PID12_09355) letA 1933359..1934015 (+) 657 WP_000611335.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  PID12_RS09360 (PID12_09360) uvrC 1934012..1935844 (+) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  PID12_RS09365 (PID12_09365) pgsA 1935901..1936449 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  PID12_RS09385 (PID12_09385) yecA 1937099..1937764 (+) 666 WP_000847902.1 UPF0149 family protein YecA -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23892.65 Da        Isoelectric Point: 6.9614

>NTDB_id=708583 PID12_RS09355 WP_000611335.1 1933359..1934015(+) (letA) [Escherichia coli strain DETEC-P169]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRTNAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=708583 PID12_RS09355 WP_000611335.1 1933359..1934015(+) (letA) [Escherichia coli strain DETEC-P169]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGACAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-115)

Bacterial regulatory proteins, luxR family (GerE)

(149-204)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q3Z2T8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

51.208

94.954

0.486
  letA Legionella pneumophila strain ERS1305867

51.208

94.954

0.486