Detailed information NTG0708536

Bioinformatically predicted

Overview

• Name: cytR
• Type: Regulator
• Locus tag: PIC26_RS21745
• Genome accession: NZ_CP116159
• Coordinates: 4525384..4526409 (+)
• Length: 341 a.a.
• NCBI ID: WP_000644904.1
• Uniprot ID: P0ACN8
• Organism: Escherichia coli strain DETEC-P351
• Function: promote competence gene expression (predicted from homology) Competence regulation

Genomic Context

Location: 4520384..4531409

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
PIC26_RS21725 (PIC26_21720)	metJ	4521445..4521762 (+)	318	WP_000852812.1	met regulon transcriptional regulator MetJ	-
PIC26_RS21730 (PIC26_21725)	yiiX	4521946..4522554 (+)	609	WP_000797353.1	YiiX family permuted papain-like enzyme	-
PIC26_RS21735 (PIC26_21730)	rpmE	4522615..4522827 (-)	213	WP_000710769.1	50S ribosomal protein L31	-
PIC26_RS21740 (PIC26_21735)	priA	4523030..4525228 (+)	2199	WP_001333520.1	primosomal protein N'	Machinery gene
PIC26_RS21745 (PIC26_21740)	cytR	4525384..4526409 (+)	1026	WP_000644904.1	DNA-binding transcriptional regulator CytR	Regulator
PIC26_RS21750 (PIC26_21745)	ftsN	4526501..4527460 (+)	960	WP_000068828.1	cell division protein FtsN	-
PIC26_RS21755 (PIC26_21750)	hslV	4527553..4528083 (+)	531	WP_000208242.1	ATP-dependent protease subunit HslV	-
PIC26_RS21760 (PIC26_21755)	hslU	4528093..4529424 (+)	1332	WP_001293341.1	HslU--HslV peptidase ATPase subunit	-
PIC26_RS21765 (PIC26_21760)	menA	4529491..4530417 (+)	927	WP_000139496.1	1,4-dihydroxy-2-naphthoate polyprenyltransferase	-
PIC26_RS21770 (PIC26_21765)	rraA	4530510..4530995 (+)	486	WP_000872908.1	ribonuclease E activity regulator RraA	-
PIC26_RS21775 (PIC26_21770)	zapB	4531080..4531325 (-)	246	WP_001296623.1	septal ring assembly protein ZapB	-

Sequence

Protein

• Length: 341 a.a.
• Molecular weight: 37819.78 Da
• Isoelectric Point: 6.3842

>NTDB_id=708536 PIC26_RS21745 WP_000644904.1 4525384..4526409(+) (cytR) [Escherichia coli strain DETEC-P351]
MKAKKQETAATMKDVALKAKVSTATVSRALMNPDKVSQATRNRVEKAAREVGYLPQPMGRNVKRNESRTILVIVPDICDP
FFSEIIRGIEVTAANHGYLVLIGDCAHQNQQEKTFIDLIITKQIDGMLLLGSRLPFDASIEEQRNLPPMVMANEFAPELE
LPTVHIDNLTAAFDAVNYLYEQGHKRIGCIAGPEEMPLCHYRLQGYVQALRRCGIMVDPQYIARGDFTFEAGSKAMQQLL
DLPQPPTAVFCHSDVMALGALSQAKRQGLKVPEDLSIIGFDNIDLTQFCDPPLTTIAQPRYEIGREAMLLLLDQMQGQHV
GSGSRLMDCELIIRGSTRALP

Nucleotide

• Length: 1026 bp

>NTDB_id=708536 PIC26_RS21745 WP_000644904.1 4525384..4526409(+) (cytR) [Escherichia coli strain DETEC-P351]
GTGAAAGCGAAGAAGCAGGAAACTGCCGCGACCATGAAAGACGTTGCCCTCAAGGCAAAAGTCTCTACAGCGACCGTCTC
CCGAGCATTAATGAATCCCGATAAAGTCTCCCAGGCCACCCGTAATCGGGTTGAAAAAGCGGCCCGGGAAGTGGGTTATT
TACCGCAGCCTATGGGGCGCAACGTCAAGCGTAATGAATCCCGCACCATTCTGGTGATTGTCCCGGATATCTGCGATCCC
TTCTTTAGCGAAATTATTCGCGGTATCGAAGTTACGGCGGCAAATCACGGATATCTGGTGCTGATTGGCGACTGTGCGCA
TCAAAATCAGCAGGAAAAAACCTTTATCGATTTGATCATCACCAAGCAAATTGATGGCATGTTGTTGCTGGGTTCAAGGC
TGCCGTTTGATGCCAGCATTGAGGAACAGCGTAATCTGCCGCCGATGGTGATGGCGAACGAATTTGCACCGGAGCTGGAG
CTGCCTACAGTTCATATCGACAATCTGACCGCCGCATTTGATGCAGTAAATTATTTATATGAGCAAGGGCATAAACGGAT
TGGCTGTATAGCCGGTCCCGAAGAGATGCCGCTGTGTCACTACCGCCTGCAAGGCTATGTTCAGGCGCTGCGTCGCTGCG
GCATTATGGTTGATCCGCAATACATCGCCCGTGGCGACTTCACCTTCGAAGCCGGAAGCAAAGCGATGCAGCAGCTGCTT
GATCTTCCACAACCGCCTACTGCTGTCTTCTGCCATAGCGATGTGATGGCGCTCGGCGCACTTTCTCAGGCAAAACGCCA
GGGGCTGAAAGTCCCGGAAGACCTTTCCATAATCGGTTTTGATAACATCGACCTGACGCAATTTTGTGATCCGCCGCTGA
CAACCATCGCGCAGCCGCGTTACGAAATCGGTCGGGAAGCTATGCTGTTATTGCTTGATCAAATGCAGGGGCAACACGTT
GGCAGTGGCTCTCGTTTAATGGACTGCGAACTTATCATCCGGGGATCAACACGCGCGTTACCTTAA

Domains

Predicted by InterProScan.

• Bacterial regulatory proteins, lacI family (LacI) (11-56)

• Periplasmic binding protein-like domain (Peripla_BP_3) (176-337)

3D structure

• AlphaFold DB: P0ACN8

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
cytR	Vibrio parahaemolyticus RIMD 2210633	64.179	98.24	0.63
cytR	Vibrio cholerae C6706	65.443	95.894	0.628