Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   PIB57_RS10095 Genome accession   NZ_CP116123
Coordinates   2126392..2127048 (+) Length   218 a.a.
NCBI ID   WP_000611328.1    Uniprot ID   P66797
Organism   Escherichia coli strain DETEC-P666     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2121392..2132048
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  PIB57_RS10065 (PIB57_10065) dcyD 2122272..2123258 (+) 987 WP_021561318.1 D-cysteine desulfhydrase -
  PIB57_RS10070 (PIB57_10070) tcyL 2123273..2123941 (+) 669 WP_001158231.1 cystine ABC transporter permease -
  PIB57_RS10075 (PIB57_10075) tcyN 2123938..2124690 (+) 753 WP_001272994.1 L-cystine ABC transporter ATP-binding protein TcyN -
  PIB57_RS10080 (PIB57_10080) sdiA 2124920..2125642 (+) 723 WP_001154271.1 transcriptional regulator SdiA -
  PIB57_RS10085 (PIB57_10085) yecF 2125709..2125933 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  PIB57_RS10090 (PIB57_10090) yecU 2125920..2126096 (-) 177 WP_000590347.1 protein YecU -
  PIB57_RS10095 (PIB57_10095) letA 2126392..2127048 (+) 657 WP_000611328.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  PIB57_RS10100 (PIB57_10100) uvrC 2127045..2128877 (+) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  PIB57_RS10105 (PIB57_10105) pgsA 2128934..2129482 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  PIB57_RS10125 (PIB57_10125) - 2130189..2130920 (-) 732 WP_001595862.1 hypothetical protein -
  PIB57_RS10130 (PIB57_10130) - 2131001..2131684 (+) 684 Protein_1985 integrase arm-type DNA-binding domain-containing protein -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23862.63 Da        Isoelectric Point: 6.9614

>NTDB_id=708176 PIB57_RS10095 WP_000611328.1 2126392..2127048(+) (letA) [Escherichia coli strain DETEC-P666]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRANAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=708176 PIB57_RS10095 WP_000611328.1 2126392..2127048(+) (letA) [Escherichia coli strain DETEC-P666]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGGCAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCTGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATCCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P66797

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

50.725

94.954

0.482
  letA Legionella pneumophila strain ERS1305867

50.725

94.954

0.482