Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   PIC78_RS13120 Genome accession   NZ_CP116094
Coordinates   2676018..2676674 (-) Length   218 a.a.
NCBI ID   WP_000611328.1    Uniprot ID   P66797
Organism   Escherichia coli strain DETEC-S560     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2671018..2681674
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  PIC78_RS13090 (PIC78_13085) yecA 2672270..2672935 (-) 666 WP_000847902.1 UPF0149 family protein YecA -
  PIC78_RS13110 (PIC78_13105) pgsA 2673584..2674132 (-) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  PIC78_RS13115 (PIC78_13110) uvrC 2674189..2676021 (-) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  PIC78_RS13120 (PIC78_13115) letA 2676018..2676674 (-) 657 WP_000611328.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  PIC78_RS25170 - 2676816..2676932 (+) 117 WP_001302039.1 hypothetical protein -
  PIC78_RS13125 (PIC78_13120) yecU 2676970..2677146 (+) 177 WP_000590344.1 protein YecU -
  PIC78_RS13130 (PIC78_13125) yecF 2677133..2677357 (+) 225 WP_000106474.1 DUF2594 family protein YecF -
  PIC78_RS13135 (PIC78_13130) sdiA 2677425..2678147 (-) 723 WP_001154260.1 transcriptional regulator SdiA -
  PIC78_RS13140 (PIC78_13135) tcyN 2678377..2679129 (-) 753 WP_001272994.1 L-cystine ABC transporter ATP-binding protein TcyN -
  PIC78_RS13145 (PIC78_13140) tcyL 2679126..2679794 (-) 669 WP_001158220.1 cystine ABC transporter permease -
  PIC78_RS13150 (PIC78_13145) dcyD 2679809..2680795 (-) 987 WP_001128215.1 D-cysteine desulfhydrase -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23862.63 Da        Isoelectric Point: 6.9614

>NTDB_id=707674 PIC78_RS13120 WP_000611328.1 2676018..2676674(-) (letA) [Escherichia coli strain DETEC-S560]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRANAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=707674 PIC78_RS13120 WP_000611328.1 2676018..2676674(-) (letA) [Escherichia coli strain DETEC-S560]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGTCGGGCAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P66797

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

50.725

94.954

0.482
  letA Legionella pneumophila strain ERS1305867

50.725

94.954

0.482