Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   PIC22_RS01255 Genome accession   NZ_CP116088
Coordinates   236094..236750 (+) Length   218 a.a.
NCBI ID   WP_000611335.1    Uniprot ID   Q3Z2T8
Organism   Escherichia coli strain DETEC-S565     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 231094..241750
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  PIC22_RS01225 (PIC22_01225) dcyD 231974..232960 (+) 987 WP_001128215.1 D-cysteine desulfhydrase -
  PIC22_RS01230 (PIC22_01230) tcyL 232975..233643 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  PIC22_RS01235 (PIC22_01235) tcyN 233640..234392 (+) 753 WP_001272986.1 L-cystine ABC transporter ATP-binding protein TcyN -
  PIC22_RS01240 (PIC22_01240) sdiA 234622..235344 (+) 723 WP_001154267.1 transcriptional regulator SdiA -
  PIC22_RS01245 (PIC22_01245) yecF 235411..235635 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  PIC22_RS01250 (PIC22_01250) yecU 235622..235798 (-) 177 WP_000590347.1 protein YecU -
  PIC22_RS25460 - 235881..235952 (-) 72 Protein_245 transcriptional regulator -
  PIC22_RS01255 (PIC22_01255) letA 236094..236750 (+) 657 WP_000611335.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  PIC22_RS01260 (PIC22_01260) uvrC 236747..238579 (+) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  PIC22_RS01265 (PIC22_01265) pgsA 238636..239184 (+) 549 WP_001160188.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  PIC22_RS01285 (PIC22_01285) - 240179..240460 (+) 282 WP_071589622.1 hypothetical protein -
  PIC22_RS01290 (PIC22_01290) - 240652..240792 (-) 141 WP_000078920.1 Hok/Gef family protein -
  PIC22_RS01295 (PIC22_01295) - 240983..241243 (-) 261 WP_000488113.1 ogr/Delta-like zinc finger family protein -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23892.65 Da        Isoelectric Point: 6.9614

>NTDB_id=707567 PIC22_RS01255 WP_000611335.1 236094..236750(+) (letA) [Escherichia coli strain DETEC-S565]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRTNAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=707567 PIC22_RS01255 WP_000611335.1 236094..236750(+) (letA) [Escherichia coli strain DETEC-S565]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGACAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-115)

Bacterial regulatory proteins, luxR family (GerE)

(149-204)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q3Z2T8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

51.208

94.954

0.486
  letA Legionella pneumophila strain ERS1305867

51.208

94.954

0.486