Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   PIC49_RS09810 Genome accession   NZ_CP116074
Coordinates   2072561..2073217 (+) Length   218 a.a.
NCBI ID   WP_000611328.1    Uniprot ID   P66797
Organism   Escherichia coli strain DETEC-S586     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2067561..2078217
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  PIC49_RS09780 (PIC49_09780) dcyD 2068440..2069426 (+) 987 WP_001128228.1 D-cysteine desulfhydrase -
  PIC49_RS09785 (PIC49_09785) tcyL 2069441..2070109 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  PIC49_RS09790 (PIC49_09790) tcyN 2070106..2070858 (+) 753 WP_001272982.1 L-cystine ABC transporter ATP-binding protein TcyN -
  PIC49_RS09795 (PIC49_09795) sdiA 2071088..2071810 (+) 723 WP_001154273.1 transcriptional regulator SdiA -
  PIC49_RS09800 (PIC49_09800) yecF 2071878..2072102 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  PIC49_RS09805 (PIC49_09805) yecU 2072089..2072265 (-) 177 WP_000590347.1 protein YecU -
  PIC49_RS09810 (PIC49_09810) letA 2072561..2073217 (+) 657 WP_000611328.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  PIC49_RS09815 (PIC49_09815) uvrC 2073214..2075046 (+) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  PIC49_RS09820 (PIC49_09820) pgsA 2075103..2075651 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  PIC49_RS09840 (PIC49_09840) yecA 2076301..2076966 (+) 666 WP_000847882.1 UPF0149 family protein YecA -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23862.63 Da        Isoelectric Point: 6.9614

>NTDB_id=707433 PIC49_RS09810 WP_000611328.1 2072561..2073217(+) (letA) [Escherichia coli strain DETEC-S586]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRANAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=707433 PIC49_RS09810 WP_000611328.1 2072561..2073217(+) (letA) [Escherichia coli strain DETEC-S586]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGGCAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACGGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTAGTGAGTGCGATCCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P66797

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

50.725

94.954

0.482
  letA Legionella pneumophila strain ERS1305867

50.725

94.954

0.482