Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   PID00_RS06640 Genome accession   NZ_CP116067
Coordinates   1264177..1264833 (-) Length   218 a.a.
NCBI ID   WP_000611328.1    Uniprot ID   P66797
Organism   Escherichia coli strain DETEC-S792     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1259177..1269833
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  PID00_RS06610 (PID00_06610) yecA 1260428..1261093 (-) 666 WP_000847877.1 UPF0149 family protein YecA -
  PID00_RS06630 (PID00_06630) pgsA 1261743..1262291 (-) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  PID00_RS06635 (PID00_06635) uvrC 1262348..1264180 (-) 1833 WP_001283427.1 excinuclease ABC subunit UvrC Machinery gene
  PID00_RS06640 (PID00_06640) letA 1264177..1264833 (-) 657 WP_000611328.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  PID00_RS06645 (PID00_06645) yecU 1265129..1265305 (+) 177 WP_000590347.1 protein YecU -
  PID00_RS06650 (PID00_06650) yecF 1265292..1265516 (+) 225 WP_000106474.1 DUF2594 family protein YecF -
  PID00_RS06655 (PID00_06655) sdiA 1265583..1266305 (-) 723 WP_001563516.1 transcriptional regulator SdiA -
  PID00_RS06660 (PID00_06660) tcyN 1266535..1267287 (-) 753 WP_001272991.1 L-cystine ABC transporter ATP-binding protein TcyN -
  PID00_RS06665 (PID00_06665) tcyL 1267284..1267952 (-) 669 WP_001158220.1 cystine ABC transporter permease -
  PID00_RS06670 (PID00_06670) dcyD 1267967..1268953 (-) 987 WP_001128215.1 D-cysteine desulfhydrase -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23862.63 Da        Isoelectric Point: 6.9614

>NTDB_id=707237 PID00_RS06640 WP_000611328.1 1264177..1264833(-) (letA) [Escherichia coli strain DETEC-S792]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRANAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=707237 PID00_RS06640 WP_000611328.1 1264177..1264833(-) (letA) [Escherichia coli strain DETEC-S792]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGAGAGGCATCGTGCGGTGAAGACGCCGTTAAATGGTGCCGGGCAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGCCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTTAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTTGTGAGTGCGATCCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P66797

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

50.725

94.954

0.482
  letA Legionella pneumophila strain ERS1305867

50.725

94.954

0.482