Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   PGH49_RS09615 Genome accession   NZ_CP116035
Coordinates   2032451..2033107 (+) Length   218 a.a.
NCBI ID   WP_000611328.1    Uniprot ID   P66797
Organism   Escherichia coli strain FAH     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2027451..2038107
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  PGH49_RS09585 (PGH49_09585) dcyD 2028330..2029316 (+) 987 WP_001128237.1 D-cysteine desulfhydrase -
  PGH49_RS09590 (PGH49_09590) tcyL 2029331..2029999 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  PGH49_RS09595 (PGH49_09595) tcyN 2029996..2030748 (+) 753 WP_001273000.1 L-cystine ABC transporter ATP-binding protein TcyN -
  PGH49_RS09600 (PGH49_09600) sdiA 2030978..2031700 (+) 723 WP_001154255.1 transcriptional regulator SdiA -
  PGH49_RS09605 (PGH49_09605) yecF 2031768..2031992 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  PGH49_RS09610 (PGH49_09610) yecU 2031979..2032155 (-) 177 WP_001307856.1 protein YecU -
  PGH49_RS09615 (PGH49_09615) letA 2032451..2033107 (+) 657 WP_000611328.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  PGH49_RS09620 (PGH49_09620) uvrC 2033104..2034936 (+) 1833 WP_001773939.1 excinuclease ABC subunit UvrC Machinery gene
  PGH49_RS09625 (PGH49_09625) pgsA 2034993..2035541 (+) 549 WP_001538881.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  PGH49_RS09645 (PGH49_09645) yecA 2036190..2036855 (+) 666 WP_000847877.1 UPF0149 family protein YecA -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23862.63 Da        Isoelectric Point: 6.9614

>NTDB_id=707018 PGH49_RS09615 WP_000611328.1 2032451..2033107(+) (letA) [Escherichia coli strain FAH]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRANAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=707018 PGH49_RS09615 WP_000611328.1 2032451..2033107(+) (letA) [Escherichia coli strain FAH]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAATGGTGCCGGGCAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGAGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTTAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGATATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P66797

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

50.725

94.954

0.482
  letA Legionella pneumophila strain ERS1305867

50.725

94.954

0.482