Detailed information    

insolico Bioinformatically predicted

Overview

Name   hexB   Type   Machinery gene
Locus tag   H7679_RS00355 Genome accession   NZ_AP023392
Coordinates   61124..63061 (+) Length   645 a.a.
NCBI ID   WP_063725144.1    Uniprot ID   -
Organism   Streptococcus suis strain DAT300     
Function   DNA mismatch repair (predicted from homology)   
Homologous recombination

Genomic Context

Location: 56124..68061
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  H7679_RS00335 (DAT300_00490) - 56238..56861 (+) 624 WP_024395312.1 HAD-IA family hydrolase -
  H7679_RS00340 (DAT300_00500) comR 56966..57865 (+) 900 WP_015646238.1 helix-turn-helix domain-containing protein Regulator
  H7679_RS00345 (DAT300_00510) - 58072..59292 (+) 1221 WP_024395311.1 bifunctional folylpolyglutamate synthase/dihydrofolate synthase -
  H7679_RS00350 (DAT300_00520) - 59483..61006 (+) 1524 WP_063725143.1 hypothetical protein -
  H7679_RS00355 (DAT300_00530) hexB 61124..63061 (+) 1938 WP_063725144.1 DNA mismatch repair endonuclease MutL Machinery gene
  H7679_RS00360 (DAT300_00540) ruvA 63100..63690 (+) 591 WP_063725145.1 Holliday junction branch migration protein RuvA Machinery gene
  H7679_RS00365 (DAT300_00550) - 63849..64418 (+) 570 WP_014637285.1 DNA-3-methyladenine glycosylase I -
  H7679_RS00370 (DAT300_00560) cinA 64455..65636 (+) 1182 WP_044685818.1 competence/damage-inducible protein A Machinery gene
  H7679_RS00375 (DAT300_00570) recA 65688..66839 (+) 1152 WP_029172053.1 recombinase RecA Machinery gene
  H7679_RS00380 (DAT300_00580) spx 67075..67473 (+) 399 WP_002939362.1 transcriptional regulator Spx -
  H7679_RS00385 (DAT300_00590) - 67573..67839 (+) 267 WP_002939360.1 IreB family regulatory phosphoprotein -

Sequence

Protein


Download         Length: 645 a.a.        Molecular weight: 72851.08 Da        Isoelectric Point: 5.2313

>NTDB_id=70699 H7679_RS00355 WP_063725144.1 61124..63061(+) (hexB) [Streptococcus suis strain DAT300]
MSHIIELPEILANQIAAGEVIERPASVVKELVENSIDAGASQIEISVEEAGLKMIQITDNGEGIAPDEVALALRRHATSK
IKSQSDLFRIRTLGFRGEALPSIASVSHMIIETATADSAHGLHLEAKGGVIEKEEPVSRPVGTQITVSDLFYNTPARLKY
VRSQQAELSHIVDVVNRLSLAHPEIAFVLVNEGRELIRTAGTGKLRQAISGIYGIASAKKMVEIEAEDLDFQISGYVSLP
ELTRANRNYISIFINGRYIKNFLLNRAILEGYGSKLMVGRFPLAVISIEIDPYLADVNVHPTKQEVRISKEKELMTLIRE
AISQALKEQDLIPDALENLAQSSTRPKVKAEQGTLPLREPKIYYDTIKQDFFLKPDVVAEDVKPLEEDRQEIVESPVENK
PTSVQFAERQSVESGDQEHPNLSAKELAKLADKLDREETSTFPELEYFGQMHGTYLFAQGKTGLYIIDQHAAQERVKYEY
YREKIGQVDNSAQQLLVPYIFEFPQNDALNLVHKMDALRQVGVNLEEYGANQFILREHPIWMKEEEIESGIYEMCDMLLL
TDQVSIKQYRAELAIMMSCKRSIKANHALDDYSARDLLRQLSYCQNPYNCPHGRPVLVHFSKSDMEKMFRRIQENHTSLR
ELGKY

Nucleotide


Download         Length: 1938 bp        

>NTDB_id=70699 H7679_RS00355 WP_063725144.1 61124..63061(+) (hexB) [Streptococcus suis strain DAT300]
ATGTCACATATTATTGAACTACCAGAAATACTAGCCAACCAGATTGCGGCTGGTGAGGTCATTGAGCGACCAGCCAGTGT
GGTTAAGGAGTTGGTGGAAAATTCCATTGACGCAGGGGCTAGTCAGATTGAAATTAGTGTTGAAGAGGCTGGCCTTAAAA
TGATTCAAATTACGGATAACGGTGAGGGGATTGCCCCTGATGAAGTAGCGCTTGCCCTCCGCCGTCACGCCACCAGTAAG
ATAAAAAGTCAATCGGATTTGTTTCGTATTCGCACCCTCGGTTTTCGTGGAGAAGCTCTGCCCTCCATTGCCTCTGTCAG
TCATATGATCATTGAGACAGCTACGGCAGACTCTGCACACGGACTTCATTTGGAGGCCAAAGGTGGTGTCATCGAGAAAG
AGGAGCCAGTTAGTCGTCCAGTTGGTACGCAGATTACTGTTTCGGATTTATTTTACAATACCCCTGCTCGTCTCAAATAT
GTTCGCAGTCAACAGGCTGAATTATCACATATTGTTGATGTTGTAAATCGATTGAGTCTAGCTCATCCGGAAATAGCTTT
TGTCTTAGTAAACGAAGGACGAGAATTAATTAGAACTGCAGGGACAGGGAAACTTCGTCAGGCAATTTCAGGGATTTATG
GGATTGCTTCAGCCAAAAAAATGGTTGAAATTGAGGCAGAAGATCTGGATTTTCAGATTTCAGGTTATGTTTCCTTGCCA
GAGTTGACTCGTGCCAACCGCAACTACATTTCCATTTTCATCAACGGTCGTTATATCAAGAATTTTTTGCTGAATCGAGC
AATTTTGGAAGGTTACGGCAGTAAGTTGATGGTTGGACGCTTTCCGTTGGCAGTGATTTCTATAGAAATTGACCCCTATC
TTGCTGATGTCAATGTGCATCCGACCAAGCAGGAAGTTCGCATCTCCAAGGAAAAAGAACTCATGACCTTGATTCGAGAG
GCGATTAGTCAAGCGCTTAAAGAGCAGGACTTGATACCAGATGCTCTTGAGAATTTAGCTCAGTCAAGTACTCGACCAAA
AGTAAAAGCAGAGCAAGGCACCTTACCACTCAGAGAGCCAAAAATCTATTATGATACGATTAAGCAAGACTTTTTCTTAA
AACCAGACGTGGTCGCTGAGGATGTCAAACCTCTCGAAGAGGATAGGCAAGAGATTGTTGAGTCGCCTGTCGAAAATAAA
CCGACATCCGTTCAATTTGCAGAACGTCAGTCGGTGGAATCAGGAGATCAGGAGCATCCTAATCTAAGTGCAAAAGAATT
GGCAAAACTGGCAGATAAATTAGACCGGGAGGAAACATCGACATTTCCAGAGTTAGAATATTTTGGTCAAATGCATGGGA
CGTATTTATTTGCACAAGGCAAGACAGGACTTTATATCATTGACCAGCATGCCGCACAAGAACGGGTCAAATACGAATAC
TATCGTGAGAAAATTGGACAGGTTGACAATTCAGCTCAACAGTTATTGGTGCCGTATATTTTTGAATTTCCGCAGAATGA
TGCCCTTAACCTTGTCCACAAAATGGATGCTCTTCGTCAAGTTGGTGTCAACTTAGAAGAATATGGAGCTAATCAATTTA
TTCTGCGTGAACATCCTATTTGGATGAAGGAAGAGGAGATTGAGTCTGGCATCTATGAGATGTGTGACATGTTGCTCTTG
ACGGATCAGGTGTCAATCAAGCAGTATCGGGCAGAACTGGCCATCATGATGTCTTGTAAACGGTCGATCAAGGCCAACCA
TGCTTTGGATGATTATTCGGCGCGTGATTTATTGAGACAATTGTCTTACTGCCAAAATCCCTATAACTGCCCGCACGGTC
GCCCAGTCTTAGTGCATTTTAGCAAATCGGATATGGAAAAAATGTTCCGTCGCATTCAAGAAAATCACACGAGTTTGCGA
GAATTGGGCAAGTATTAA

Domains

Predicted by InterProScan.

MutL C terminal dimerisation domain (MutL_C)

(447-589)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c_3)

(25-124)

DNA mismatch repair protein, C-terminal domain (DNA_mis_repair)

(210-326)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  hexB Streptococcus pneumoniae R6

72.462

100

0.73

Multiple sequence alignment