Detailed information NTG0706752

Bioinformatically predicted

Overview

• Name: hexB
• Type: Machinery gene
• Locus tag: PF976_RS09455
• Genome accession: NZ_CP116011
• Coordinates: 1764914..1766791 (+)
• Length: 625 a.a.
• NCBI ID: WP_013352326.1
• Uniprot ID: A0A9P1JH09
• Organism: Bacillus amyloliquefaciens strain SRCM124317
• Function: DNA mismatch repair (predicted from homology) Homologous recombination

Genomic Context

Location: 1759914..1771791

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
PF976_RS09440 (PF976_09440)	ymcA	1760967..1761398 (+)	432	WP_013352323.1	RicAFT regulatory complex protein RicA family protein	Regulator
PF976_RS09445 (PF976_09445)	cotE	1761652..1762197 (+)	546	WP_013352324.1	outer spore coat protein CotE	-
PF976_RS09450 (PF976_09450)	hexA	1762313..1764898 (+)	2586	WP_014470386.1	DNA mismatch repair protein MutS	Machinery gene
PF976_RS09455 (PF976_09455)	hexB	1764914..1766791 (+)	1878	WP_013352326.1	DNA mismatch repair endonuclease MutL	Machinery gene
PF976_RS09460 (PF976_09460)	-	1767257..1767934 (+)	678	WP_013352327.1	MBL fold metallo-hydrolase	-
PF976_RS09465 (PF976_09465)	fabD	1768239..1769108 (+)	870	WP_013352328.1	ACP S-malonyltransferase	-
PF976_RS09470 (PF976_09470)	-	1769243..1770217 (+)	975	WP_013352329.1	acyltransferase domain-containing protein	-

Sequence

Protein

• Length: 625 a.a.
• Molecular weight: 70353.50 Da
• Isoelectric Point: 5.9217

>NTDB_id=706752 PF976_RS09455 WP_013352326.1 1764914..1766791(+) (hexB) [Bacillus amyloliquefaciens strain SRCM124317]
MAKVIQLSDELSNKIAAGEVVERPASVVKELVENAIDANSTVIEIDIEEAGLSSIRVLDNGEGMETEDCKRAFRRHATSK
IKDENDLFRVRTLGFRGEALPSIASVSHLEIKTSIGEGAGTHLILQGGNMISEQRTSSRKGTEIIVTNLFFNTPARLKYM
KTVHTELGNITDVVNRIALAHPEVSIRLRHQGKNLLQTNGNGDVRHVLAAIYGTAVAKKMIPLHVSSLDFEVKGYIALPE
ITRASRNYMSSVINGRYIKNFPLVKAVHEGYHTLLPIGRHPITFIEITMDPILVDVNVHPSKLEVRLSKETELHELIRDG
IKEVFQKQRLIPSAQLPKKSAPAPIKNEQQFMTFGESEPERKLPEKTPEPSYSPMKLSSVVKEPAPVTEEEFHPNEADHE
VPSETSMPEMAAPVSDIPAPEEEAVSEEIQEERVPVMYPIGQMHGTYILAQNENGLYIIDQHAAQERIKYEYFREKVGQV
EPEVQDMIVPLTFHYAANEALIIEQHQHELESVGVFLEAFGTNSYIVRCHPAWFPKGEEAELIEEIIQQVLDAKQIDIKK
LREEAAIMMSCKGSIKANRHLRNDEIKALLDDLRRTADPFTCPHGRPIIIHHSTYEMEKMFKRVM

Nucleotide

• Length: 1878 bp

>NTDB_id=706752 PF976_RS09455 WP_013352326.1 1764914..1766791(+) (hexB) [Bacillus amyloliquefaciens strain SRCM124317]
TTGGCAAAAGTCATCCAGCTGTCAGATGAGCTTTCAAATAAAATAGCGGCCGGTGAGGTGGTGGAACGGCCCGCCTCTGT
CGTTAAAGAATTGGTGGAAAACGCAATCGACGCAAACAGCACAGTCATTGAAATCGATATAGAGGAAGCGGGGCTTTCGT
CGATTCGGGTGCTCGACAACGGCGAAGGTATGGAAACCGAGGATTGCAAGCGGGCTTTCCGCCGCCATGCGACCAGTAAA
ATCAAAGATGAAAATGACCTGTTCCGGGTGAGAACACTCGGTTTCCGCGGAGAAGCTTTGCCAAGTATCGCGTCTGTTTC
TCATCTGGAAATCAAAACGAGCATCGGCGAGGGAGCGGGAACTCATCTCATTCTTCAGGGCGGGAATATGATTTCTGAAC
AGAGAACTTCCAGCAGAAAAGGGACGGAGATCATCGTCACTAACCTGTTTTTCAATACACCCGCCAGATTAAAATATATG
AAAACCGTGCATACGGAGCTCGGCAATATTACGGATGTCGTCAACCGGATCGCTCTTGCGCATCCGGAAGTATCGATCCG
CCTCCGCCATCAGGGGAAAAACCTGCTGCAGACAAACGGAAACGGGGACGTGCGCCATGTGCTGGCCGCAATTTACGGGA
CGGCGGTTGCGAAAAAAATGATACCGCTCCATGTCAGCTCACTTGATTTTGAAGTCAAGGGCTACATTGCGCTGCCGGAA
ATCACGCGTGCATCCAGAAACTACATGTCATCTGTCATTAACGGAAGATACATTAAGAATTTCCCGCTTGTAAAAGCGGT
GCATGAGGGCTATCACACGCTTCTGCCGATCGGCCGCCATCCGATTACGTTTATCGAAATTACGATGGATCCGATTTTAG
TCGATGTCAATGTCCATCCGTCGAAGCTTGAAGTCCGCCTCAGCAAAGAGACGGAACTGCATGAGCTGATCCGTGACGGC
ATAAAGGAAGTTTTTCAAAAGCAGCGGCTTATTCCAAGCGCCCAGCTTCCGAAAAAATCAGCGCCGGCACCGATCAAAAA
TGAACAGCAATTTATGACGTTCGGTGAAAGTGAGCCTGAGCGGAAACTGCCTGAAAAAACGCCGGAGCCGTCTTACTCGC
CGATGAAGCTGAGTTCGGTCGTAAAAGAGCCGGCGCCGGTAACAGAAGAAGAGTTTCACCCAAATGAAGCGGATCATGAA
GTGCCGTCGGAAACCAGCATGCCGGAAATGGCTGCGCCTGTTTCTGATATTCCGGCGCCGGAAGAGGAAGCTGTCTCCGA
AGAAATACAGGAAGAAAGAGTTCCGGTCATGTATCCGATCGGCCAAATGCACGGGACATATATTTTAGCCCAAAACGAAA
ACGGCCTGTATATCATTGACCAGCATGCGGCCCAAGAGCGGATTAAATACGAATATTTCCGGGAAAAAGTCGGGCAGGTT
GAGCCTGAAGTGCAGGATATGATCGTGCCGCTCACCTTTCACTATGCGGCAAATGAAGCGCTTATCATTGAACAGCATCA
GCATGAGCTTGAAAGTGTAGGGGTATTTTTAGAAGCTTTCGGCACTAACAGCTATATCGTCCGCTGCCATCCGGCCTGGT
TTCCAAAAGGGGAAGAAGCTGAACTGATTGAAGAAATCATTCAGCAGGTGCTTGACGCCAAACAGATCGACATTAAAAAA
CTTCGGGAGGAAGCCGCCATAATGATGAGCTGCAAAGGCTCGATCAAAGCGAACCGTCATTTGCGCAACGATGAAATCAA
AGCGCTCTTGGACGATCTGCGCCGAACGGCAGACCCGTTCACATGCCCGCACGGCCGGCCGATCATTATTCACCATAGCA
CGTATGAGATGGAAAAGATGTTTAAACGCGTGATGTAG

Domains

Predicted by InterProScan.

• MutL C terminal dimerisation domain (MutL_C) (440-581)

• DNA mismatch repair protein, C-terminal domain (DNA_mis_repair) (209-325)

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c_3) (25-85)

3D structure

• AlphaFold DB: A0A9P1JH09

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
hexB	Streptococcus pneumoniae R6	46.368	100	0.48