Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   H7677_RS02040 Genome accession   NZ_AP023391
Coordinates   413290..413931 (+) Length   213 a.a.
NCBI ID   WP_184493896.1    Uniprot ID   -
Organism   Streptococcus suis strain DAT299     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 408290..418931
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  H7677_RS02020 (DAT299_03590) - 408590..409327 (+) 738 WP_004194145.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -
  H7677_RS02025 (DAT299_03600) pknB 409327..410985 (+) 1659 Protein_362 Stk1 family PASTA domain-containing Ser/Thr kinase -
  H7677_RS10725 - 411106..411321 (+) 216 Protein_363 serine/threonine protein kinase -
  H7677_RS02030 (DAT299_03610) liaF 411646..412305 (+) 660 WP_232088995.1 cell wall-active antibiotics response protein LiaF -
  H7677_RS02035 (DAT299_03620) - 412302..413318 (+) 1017 WP_002937028.1 sensor histidine kinase -
  H7677_RS02040 (DAT299_03630) vraR 413290..413931 (+) 642 WP_184493896.1 response regulator transcription factor Regulator
  H7677_RS02045 (DAT299_03640) - 413981..415381 (+) 1401 WP_184493898.1 bifunctional Cof-type HAD-IIB family hydrolase/peptidylprolyl isomerase -
  H7677_RS02050 (DAT299_03650) - 415383..415754 (+) 372 WP_002937017.1 S1 RNA-binding domain-containing protein -
  H7677_RS02055 (DAT299_03660) cysK 415781..416707 (-) 927 WP_002937015.1 cysteine synthase A -
  H7677_RS02060 (DAT299_03670) - 416797..417429 (-) 633 WP_015646510.1 YigZ family protein -
  H7677_RS02065 (DAT299_03680) comFA/cflA 417486..418778 (+) 1293 WP_184493900.1 DEAD/DEAH box helicase Machinery gene

Sequence

Protein


Download         Length: 213 a.a.        Molecular weight: 23746.35 Da        Isoelectric Point: 5.0067

>NTDB_id=70628 H7677_RS02040 WP_184493896.1 413290..413931(+) (vraR) [Streptococcus suis strain DAT299]
MNTIRVMLVDDHEMVRLGLKSYLNLQPDVEVVAEASDGEEGLAKALEVKPDVIVMDLVMPKMTGVEATLALLKEWPQAQI
VILTSYLDNEKIYPVLEAGARGYMLKTSSADEILAAIRKVALGEYAIETEVEKKVEHHKRHPDLHDDLTAREREILTLLA
KGYDNQRIADESFISLKTVKTHVSNILSKLAVSDRTQAVVYAFQHGLVAQADQ

Nucleotide


Download         Length: 642 bp        

>NTDB_id=70628 H7677_RS02040 WP_184493896.1 413290..413931(+) (vraR) [Streptococcus suis strain DAT299]
ATGAATACGATTCGAGTGATGCTGGTTGACGACCATGAGATGGTTCGTCTAGGATTGAAAAGTTACTTAAATTTACAGCC
AGATGTTGAAGTAGTTGCAGAAGCTAGTGATGGCGAGGAAGGTTTGGCTAAAGCATTAGAGGTTAAACCCGATGTTATAG
TGATGGACTTGGTTATGCCCAAGATGACTGGCGTAGAAGCAACCCTGGCCTTGCTGAAGGAATGGCCGCAAGCGCAGATT
GTCATCCTGACCTCCTACCTAGATAATGAAAAAATCTATCCTGTGCTGGAAGCAGGAGCTCGTGGTTATATGTTGAAAAC
GTCAAGTGCTGACGAAATCTTAGCAGCCATCCGCAAGGTAGCTCTTGGAGAATATGCTATTGAGACAGAAGTAGAGAAAA
AAGTAGAGCACCATAAACGCCACCCAGATTTACATGATGACTTGACAGCTCGTGAACGCGAAATCTTGACGCTGTTAGCC
AAGGGATATGATAATCAACGAATTGCAGATGAGTCCTTCATTTCCCTAAAAACTGTTAAGACCCATGTTTCCAATATCTT
ATCCAAACTAGCTGTTAGCGATCGTACTCAAGCAGTTGTTTATGCTTTCCAGCATGGTTTGGTGGCGCAAGCGGACCAAT
AG

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(148-202)

Response regulator receiver domain (Response_reg)

(6-118)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

55.072

97.183

0.535
  degU Bacillus subtilis subsp. subtilis str. 168

38.496

100

0.408