Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   PBU98_RS10865 Genome accession   NZ_CP115821
Coordinates   2255132..2255788 (+) Length   218 a.a.
NCBI ID   WP_000611328.1    Uniprot ID   P66797
Organism   Escherichia coli strain E1     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2250132..2260788
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  PBU98_RS10835 dcyD 2251012..2251998 (+) 987 WP_001373912.1 D-cysteine desulfhydrase -
  PBU98_RS10840 tcyL 2252013..2252681 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  PBU98_RS10845 tcyN 2252678..2253430 (+) 753 WP_001273003.1 L-cystine ABC transporter ATP-binding protein TcyN -
  PBU98_RS10850 sdiA 2253660..2254382 (+) 723 WP_001154271.1 transcriptional regulator SdiA -
  PBU98_RS10855 yecF 2254449..2254673 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  PBU98_RS10860 yecU 2254660..2254836 (-) 177 WP_000590347.1 protein YecU -
  PBU98_RS10865 letA 2255132..2255788 (+) 657 WP_000611328.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  PBU98_RS10870 uvrC 2255785..2257617 (+) 1833 WP_001595863.1 excinuclease ABC subunit UvrC Machinery gene
  PBU98_RS10875 pgsA 2257674..2258222 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  PBU98_RS10895 - 2258929..2259660 (-) 732 WP_001595862.1 hypothetical protein -
  PBU98_RS10900 - 2259741..2260424 (+) 684 Protein_2126 integrase arm-type DNA-binding domain-containing protein -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23862.63 Da        Isoelectric Point: 6.9614

>NTDB_id=706041 PBU98_RS10865 WP_000611328.1 2255132..2255788(+) (letA) [Escherichia coli strain E1]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRANAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=706041 PBU98_RS10865 WP_000611328.1 2255132..2255788(+) (letA) [Escherichia coli strain E1]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGGCAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCTGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATCCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P66797

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

50.725

94.954

0.482
  letA Legionella pneumophila strain ERS1305867

50.725

94.954

0.482