Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA   Type   Regulator
Locus tag   NLK52_RS15665 Genome accession   NZ_CP100436
Coordinates   3032514..3033158 (-) Length   214 a.a.
NCBI ID   WP_003220716.1    Uniprot ID   -
Organism   Bacillus subtilis strain MEC_B298     
Function   promoting transcription of comS (predicted from homology)   
Competence regulation

Genomic Context

Location: 3027514..3038158
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NLK52_RS15630 (NLK52_15630) mrpB 3028707..3029138 (+) 432 WP_003228819.1 Na(+)/H(+) antiporter subunit B -
  NLK52_RS15635 (NLK52_15635) mrpC 3029138..3029479 (+) 342 WP_003220730.1 Na(+)/H(+) antiporter subunit C -
  NLK52_RS15640 (NLK52_15640) mrpD 3029472..3030953 (+) 1482 WP_015384516.1 Na+/H+ antiporter subunit D -
  NLK52_RS15645 (NLK52_15645) mrpE 3030959..3031435 (+) 477 WP_003228815.1 Na+/H+ antiporter subunit E -
  NLK52_RS15650 (NLK52_15650) mrpF 3031435..3031719 (+) 285 WP_003228814.1 Na(+)/H(+) antiporter subunit F1 -
  NLK52_RS15655 (NLK52_15655) mnhG 3031703..3032077 (+) 375 WP_014477830.1 monovalent cation/H(+) antiporter subunit G -
  NLK52_RS15660 (NLK52_15660) yuxO 3032116..3032496 (-) 381 WP_015483631.1 hotdog fold thioesterase -
  NLK52_RS15665 (NLK52_15665) comA 3032514..3033158 (-) 645 WP_003220716.1 two-component system response regulator ComA Regulator
  NLK52_RS15670 (NLK52_15670) comP 3033239..3035539 (-) 2301 WP_046340263.1 histidine kinase Regulator
  NLK52_RS15675 (NLK52_15675) comX 3035551..3035715 (-) 165 WP_015384519.1 competence pheromone ComX -
  NLK52_RS15680 (NLK52_15680) - 3035728..3036588 (-) 861 WP_015483633.1 polyprenyl synthetase family protein -
  NLK52_RS15685 (NLK52_15685) degQ 3036773..3036913 (-) 141 WP_003220708.1 degradation enzyme regulation protein DegQ Regulator
  NLK52_RS15690 (NLK52_15690) - 3037135..3037197 (+) 63 Protein_3034 hypothetical protein -
  NLK52_RS15695 (NLK52_15695) - 3037375..3037743 (+) 369 WP_015483634.1 hypothetical protein -

Sequence

Protein


Download         Length: 214 a.a.        Molecular weight: 24128.51 Da        Isoelectric Point: 4.6857

>NTDB_id=705453 NLK52_RS15665 WP_003220716.1 3032514..3033158(-) (comA) [Bacillus subtilis strain MEC_B298]
MKKILVIDDHPAVMEGTKTILETDSNLSVDCLSPEPSEQFIKQHDFSSYDLILMDLNLGGEVNGMELSKQILQENPHCKI
IVYTGYEVEDYFEEAIRAGLHGAISKTESKEKITQYIYHVLNGEILVDFAYFKQLMTQQKTKPAPSSQKEQDVLTPRECL
ILQEVEKGFTNQEIADALHLSKRSIEYSLTSIFNKLNVGSRTEAVLIAKSDGVL

Nucleotide


Download         Length: 645 bp        

>NTDB_id=705453 NLK52_RS15665 WP_003220716.1 3032514..3033158(-) (comA) [Bacillus subtilis strain MEC_B298]
ATGAAAAAGATACTAGTGATTGATGACCATCCGGCTGTCATGGAAGGCACCAAGACAATTTTGGAAACGGATTCGAATCT
GTCTGTTGATTGTCTCAGTCCTGAACCGAGCGAACAGTTTATCAAGCAGCATGATTTCTCGTCATATGATCTCATTTTAA
TGGATCTGAATTTAGGCGGCGAGGTCAATGGGATGGAGCTTTCTAAACAGATTTTACAAGAGAATCCTCATTGTAAAATT
ATCGTGTATACCGGTTATGAGGTCGAGGATTATTTCGAGGAAGCGATTCGTGCGGGTCTGCACGGTGCCATCAGCAAAAC
GGAATCTAAAGAAAAGATCACCCAATACATATACCACGTACTCAACGGAGAAATTTTAGTCGATTTTGCTTACTTTAAAC
AGCTGATGACTCAGCAAAAAACAAAGCCGGCTCCTTCCTCTCAAAAAGAACAAGATGTGCTCACACCTAGAGAATGCCTG
ATTCTTCAAGAAGTTGAAAAGGGATTTACAAACCAAGAAATCGCAGATGCCCTTCATTTAAGCAAGCGGTCCATTGAATA
CAGCTTGACATCGATTTTCAATAAGCTGAATGTCGGTTCCCGGACGGAAGCGGTTTTGATTGCGAAATCAGACGGTGTAC
TTTAA

Domains

Predicted by InterproScan.

Bacterial regulatory proteins, luxR family (GerE)

(152-208)

Response regulator receiver domain (Response_reg)

(4-117)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA Bacillus subtilis subsp. subtilis str. 168

100

100

1