Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   NLK52_RS06185 Genome accession   NZ_CP100436
Coordinates   1197850..1198506 (+) Length   218 a.a.
NCBI ID   WP_015383354.1    Uniprot ID   -
Organism   Bacillus subtilis strain MEC_B298     
Function   degradation of ComK (predicted from homology)   
Competence regulation

Genomic Context

Location: 1192850..1203506
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NLK52_RS06155 (NLK52_06155) oppF 1193319..1194236 (+) 918 WP_003245567.1 oligopeptide ABC transporter ATP-binding protein OppF -
  NLK52_RS06160 (NLK52_06160) yjbB 1194342..1195559 (+) 1218 WP_080030656.1 MFS transporter -
  NLK52_RS06165 (NLK52_06165) yjbC 1195723..1196298 (+) 576 WP_015383352.1 GNAT family N-acetyltransferase -
  NLK52_RS06170 (NLK52_06170) spx 1196479..1196874 (+) 396 WP_014476435.1 transcriptional regulator Spx -
  NLK52_RS06175 (NLK52_06175) yjbE 1196917..1197573 (-) 657 WP_015483086.1 TerC family protein -
  NLK52_RS06180 (NLK52_06180) - 1197743..1197883 (+) 141 WP_119122854.1 hypothetical protein -
  NLK52_RS06185 (NLK52_06185) mecA 1197850..1198506 (+) 657 WP_015383354.1 adaptor protein MecA Regulator
  NLK52_RS06190 (NLK52_06190) - 1198509..1198623 (-) 115 Protein_1159 hypothetical protein -
  NLK52_RS06195 (NLK52_06195) coiA 1198667..1199818 (+) 1152 WP_015483087.1 competence protein CoiA Machinery gene
  NLK52_RS06200 (NLK52_06200) pepF 1200048..1201877 (+) 1830 WP_003245178.1 oligoendopeptidase F -
  NLK52_RS06205 (NLK52_06205) - 1201915..1202082 (-) 168 WP_003244944.1 hypothetical protein -
  NLK52_RS06210 (NLK52_06210) spxH 1202397..1203296 (-) 900 WP_003245184.1 protease adaptor protein SpxH -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 25749.62 Da        Isoelectric Point: 4.0841

>NTDB_id=705417 NLK52_RS06185 WP_015383354.1 1197850..1198506(+) (mecA) [Bacillus subtilis strain MEC_B298]
MEIERINEHTVKFYMSYGDIEDRGFDREEIWYNRERSEELFWEVMDEVHEEEEFAVEGPLWIQVQALDKGLEIIVTKAQL
SKDGQKLELPIPEDKKQEPASEDLDALLDDFQKEEQAVNQEEKEQKLQFVLRFGDFEDVISLSNLNVNGSKTTLYSFENR
YYLYVDFCNMTDEEVENQLSILLEYATESSISIHRLEEYGKLIISEHALETIKKHFAS

Nucleotide


Download         Length: 657 bp        

>NTDB_id=705417 NLK52_RS06185 WP_015383354.1 1197850..1198506(+) (mecA) [Bacillus subtilis strain MEC_B298]
ATGGAAATTGAAAGAATTAACGAGCATACAGTAAAATTTTATATGTCTTACGGAGATATTGAAGATCGCGGTTTTGACAG
AGAAGAAATTTGGTATAACCGTGAGCGCAGTGAAGAACTTTTCTGGGAAGTCATGGATGAAGTTCATGAAGAAGAGGAAT
TCGCTGTGGAAGGCCCACTTTGGATTCAAGTTCAGGCACTGGACAAAGGATTAGAAATCATCGTCACAAAAGCCCAGCTT
TCCAAAGACGGACAAAAGCTCGAACTGCCGATTCCTGAGGATAAAAAGCAAGAACCAGCATCTGAGGATCTTGACGCCTT
GCTGGATGATTTCCAGAAAGAAGAGCAAGCTGTCAATCAGGAAGAGAAGGAGCAAAAGCTTCAATTTGTCTTGCGATTTG
GCGATTTTGAGGATGTTATTTCTCTATCTAATTTGAACGTTAACGGAAGCAAAACGACTTTATATTCGTTTGAGAACCGA
TATTATTTATATGTAGATTTTTGCAATATGACTGATGAAGAGGTTGAAAATCAGCTAAGCATCCTGCTGGAGTACGCAAC
TGAATCCTCAATCAGCATACACCGTCTTGAAGAGTACGGCAAGCTGATTATTTCAGAGCATGCTCTAGAAACGATAAAAA
AACACTTTGCATCATAA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-212)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Bacillus subtilis subsp. subtilis str. 168

99.541

100

0.995