Detailed information    

insolico Bioinformatically predicted

Overview

Name   micB   Type   Regulator
Locus tag   NLY78_RS06185 Genome accession   NZ_CP100435
Coordinates   1260303..1261652 (-) Length   449 a.a.
NCBI ID   WP_012027301.1    Uniprot ID   -
Organism   Streptococcus suis strain DE609B     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1255303..1266652
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NLY78_RS06165 (NLY78_06160) pbp2b 1255368..1257443 (-) 2076 WP_012775443.1 penicillin-binding protein PBP2B -
  NLY78_RS06170 (NLY78_06165) - 1257520..1258269 (-) 750 WP_012027298.1 ATP-binding cassette domain-containing protein -
  NLY78_RS06175 (NLY78_06170) - 1258432..1258974 (-) 543 WP_012027299.1 ATP-binding cassette domain-containing protein -
  NLY78_RS06180 (NLY78_06175) vicX 1259493..1260296 (-) 804 WP_012027300.1 MBL fold metallo-hydrolase Regulator
  NLY78_RS06185 (NLY78_06180) micB 1260303..1261652 (-) 1350 WP_012027301.1 cell wall metabolism sensor histidine kinase VicK Regulator
  NLY78_RS06190 (NLY78_06185) micA 1261645..1262349 (-) 705 WP_004298854.1 response regulator YycF Regulator
  NLY78_RS06195 (NLY78_06190) - 1262543..1263304 (+) 762 WP_012027304.1 amino acid ABC transporter ATP-binding protein -
  NLY78_RS06200 (NLY78_06195) - 1263315..1264154 (+) 840 WP_012027305.1 transporter substrate-binding domain-containing protein -
  NLY78_RS06205 (NLY78_06200) - 1264169..1264867 (+) 699 WP_012028333.1 amino acid ABC transporter permease -
  NLY78_RS06210 (NLY78_06205) - 1264882..1265541 (+) 660 WP_002935828.1 amino acid ABC transporter permease -

Sequence

Protein


Download         Length: 449 a.a.        Molecular weight: 51079.14 Da        Isoelectric Point: 4.4857

>NTDB_id=705375 NLY78_RS06185 WP_012027301.1 1260303..1261652(-) (micB) [Streptococcus suis strain DE609B]
MINQLRYLMTTAEFWFVVILIGFLIALTVLLIENYWDNKQIKQLNQKVNALIEGNYADLLDMRGSPEITDMANSLNDLSE
VIRLTHDNLEQEKTRLTSILSYMSDGVIATDRIGRIIMINDMAQKQLGLSNPKQEQYHLLEVLDLSDRYTLRDLLAQTPE
IVIDHTNENEEFLTLRANFATIRSESGLISGLVVVLHDMTEQAKEERERRLFVSNVSHELRTPLTSVKSYLEALDEGALT
ESVAPSFVKVSLDETNRMMRMITDLLSLSRIDNQVGQIDVELINFTAFVTFILNRFDQMKNADSDKVYTIVRDYQISPIW
VEIDTDKMTQVLDNILNNAIKYSPDGGTITFSMKTTDSQLIVSVSDEGLGIPKADLPRIFDRFYRVDKARSRAQGGTGLG
LAIAKEIVKQHKGFIWAKSEYGHGSTFTIVLPYSKDIALDEWDDSDEEE

Nucleotide


Download         Length: 1350 bp        

>NTDB_id=705375 NLY78_RS06185 WP_012027301.1 1260303..1261652(-) (micB) [Streptococcus suis strain DE609B]
ATGATTAATCAATTACGTTATTTAATGACCACGGCAGAATTTTGGTTTGTTGTCATTTTGATTGGCTTTCTAATTGCTCT
GACGGTCCTTTTGATTGAAAACTATTGGGATAATAAGCAAATTAAACAACTCAATCAAAAAGTCAATGCCTTAATTGAGG
GGAATTATGCAGATCTGTTAGACATGAGGGGAAGTCCTGAAATCACAGACATGGCTAATTCCCTCAATGATTTGTCCGAG
GTCATCCGCTTAACTCATGATAATTTAGAACAAGAAAAGACACGTCTGACGTCCATCCTGTCCTATATGAGTGACGGTGT
TATTGCTACAGACCGTATCGGACGGATCATCATGATTAACGATATGGCCCAGAAACAGTTGGGGTTATCTAACCCAAAGC
AGGAGCAGTATCACCTGCTAGAGGTTTTAGATTTATCAGACCGTTATACATTGAGAGATTTGTTGGCTCAGACACCTGAG
ATTGTGATTGATCACACCAATGAAAACGAAGAATTTCTGACTTTACGCGCTAATTTTGCAACGATTCGTAGTGAGAGTGG
TCTGATTTCTGGCCTGGTTGTCGTCTTGCATGATATGACCGAGCAGGCCAAGGAAGAACGGGAACGTAGGCTGTTTGTGT
CAAATGTGAGTCATGAATTGCGTACGCCATTGACTTCCGTTAAATCCTATCTAGAGGCTCTGGATGAGGGAGCGCTGACG
GAGTCTGTGGCGCCGAGTTTTGTTAAGGTATCCTTAGATGAGACCAACCGCATGATGCGGATGATTACAGATCTCCTTAG
CTTATCGCGCATTGATAATCAAGTTGGTCAGATAGATGTCGAACTGATAAACTTTACTGCTTTTGTGACCTTTATTCTTA
ACCGTTTTGACCAAATGAAAAATGCTGATTCAGATAAGGTCTATACGATTGTTCGTGACTATCAAATCAGTCCTATTTGG
GTTGAGATTGATACAGATAAGATGACTCAGGTTTTAGATAATATCTTAAATAATGCCATTAAATATTCGCCAGACGGCGG
GACAATTACCTTCAGCATGAAGACCACAGATAGCCAGTTGATTGTATCCGTATCAGACGAAGGTCTGGGGATTCCGAAAG
CAGATTTACCTAGAATTTTTGACCGATTTTATCGCGTAGACAAGGCACGATCTCGTGCCCAAGGTGGTACAGGTCTTGGT
TTAGCTATTGCAAAAGAAATCGTAAAACAACATAAGGGCTTTATCTGGGCTAAAAGCGAATATGGTCATGGCTCAACGTT
TACAATTGTCTTGCCGTATAGCAAGGACATCGCACTAGATGAGTGGGATGATTCAGATGAGGAAGAATAG

Domains

Predicted by InterproScan.

His Kinase A (phospho-acceptor) domain (HisKA)

(209-273)

PAS fold (PAS)

(96-199)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(324-434)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  micB Streptococcus pneumoniae Cp1015

69.725

97.105

0.677
  vicK Streptococcus mutans UA159

70.72

89.755

0.635