Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYB   Type   Machinery gene
Locus tag   NLY78_RS00770 Genome accession   NZ_CP100435
Coordinates   120781..121818 (+) Length   345 a.a.
NCBI ID   WP_011921719.1    Uniprot ID   -
Organism   Streptococcus suis strain DE609B     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 115781..126818
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NLY78_RS00755 (NLY78_00750) - 118490..118855 (+) 366 WP_002936568.1 DUF1033 family protein -
  NLY78_RS00760 (NLY78_00755) - 118890..119833 (-) 944 Protein_115 S66 peptidase family protein -
  NLY78_RS00765 (NLY78_00760) comYA 119919..120869 (+) 951 WP_011921718.1 competence type IV pilus ATPase ComGA Machinery gene
  NLY78_RS00770 (NLY78_00765) comYB 120781..121818 (+) 1038 WP_011921719.1 competence type IV pilus assembly protein ComGB Machinery gene
  NLY78_RS00775 (NLY78_00770) comYC 121820..122101 (+) 282 WP_011921720.1 competence type IV pilus major pilin ComGC Machinery gene
  NLY78_RS00780 (NLY78_00775) comGD 122082..122489 (+) 408 WP_011921721.1 competence type IV pilus minor pilin ComGD -
  NLY78_RS00785 (NLY78_00780) comYE 122461..122754 (+) 294 WP_011921722.1 competence type IV pilus minor pilin ComGE Machinery gene
  NLY78_RS00790 (NLY78_00785) comGF/cglF 122741..123175 (+) 435 WP_011922561.1 competence type IV pilus minor pilin ComGF Machinery gene
  NLY78_RS00795 (NLY78_00790) comGG 123153..123563 (+) 411 WP_011921724.1 competence type IV pilus minor pilin ComGG -
  NLY78_RS00800 (NLY78_00795) comYH 123620..124573 (+) 954 WP_011922562.1 class I SAM-dependent methyltransferase Machinery gene
  NLY78_RS00805 (NLY78_00800) - 124623..125810 (+) 1188 WP_012775422.1 acetate kinase -
  NLY78_RS00810 (NLY78_00805) - 126125..126676 (+) 552 WP_012774908.1 folate family ECF transporter S component -

Sequence

Protein


Download         Length: 345 a.a.        Molecular weight: 38954.94 Da        Isoelectric Point: 9.3127

>NTDB_id=705349 NLY78_RS00770 WP_011921719.1 120781..121818(+) (comYB) [Streptococcus suis strain DE609B]
MRKLIGFLQQDISVFGRQKQKKLPLARQRKVIELFNNLFASGFHLGEIVDFLKRSQLLADPYTQVLSDGLLAGKPFSSLL
ADLRFSDAVVTQVALAEVHGNTSLSLIHIQSYLENVSKVRKKLIEVATYPIILLGFLLLIMLGLKNYLLPQLEEGNAATV
LINHLPTIFLSLSGLSLVAVLAGMVWFRKTNKIKVFSCLAALPFFGKLIQTYLTAYYAREWGSLIGQGLDLPQIVGLMQE
QQSQLFREIGQDLEQSLSNGQSFHEHIKTYAFFKRELSLIVEYGQVKSKLGSELTVYAAECWEDFFSRVNRAMQLIQPLV
FLFVALMVVLIYAAMLLPIYQNMEL

Nucleotide


Download         Length: 1038 bp        

>NTDB_id=705349 NLY78_RS00770 WP_011921719.1 120781..121818(+) (comYB) [Streptococcus suis strain DE609B]
ATGCGCAAATTGATCGGCTTTTTGCAGCAGGACATATCAGTCTTCGGCAGGCAGAAACAGAAAAAATTACCCTTGGCTCG
CCAGCGTAAGGTCATTGAGCTTTTCAATAATCTTTTTGCCAGTGGTTTTCATCTGGGGGAGATTGTTGATTTCCTCAAAC
GCAGTCAGCTTCTGGCAGATCCCTATACCCAGGTCTTGTCAGACGGGTTGCTGGCAGGCAAACCCTTTTCGAGTTTGCTG
GCAGATTTGCGATTTTCAGATGCGGTGGTCACACAGGTGGCTCTAGCAGAAGTTCATGGTAATACCAGCCTGAGTTTGAT
TCATATCCAGTCCTATCTGGAAAATGTCAGCAAGGTTCGTAAAAAGCTGATTGAGGTGGCGACCTATCCGATTATATTGC
TTGGTTTTCTGCTTTTGATTATGCTTGGCTTGAAAAACTATCTTCTGCCCCAGTTGGAGGAAGGCAATGCAGCGACAGTG
CTGATTAATCATCTACCGACCATCTTTTTATCTCTAAGTGGACTTAGTTTGGTGGCGGTCTTAGCTGGTATGGTTTGGTT
TCGCAAAACCAATAAAATTAAGGTCTTTTCCTGCTTGGCAGCTCTGCCATTTTTCGGAAAACTCATCCAAACCTACCTGA
CGGCCTATTACGCCAGGGAGTGGGGGAGTTTGATTGGGCAAGGCTTGGACCTGCCGCAGATTGTGGGCTTGATGCAAGAG
CAGCAGTCGCAGCTTTTTCGGGAGATTGGCCAGGACCTGGAGCAGTCGCTTTCCAATGGTCAGAGTTTTCACGAACACAT
TAAGACCTACGCCTTTTTTAAGCGGGAGCTGAGTTTGATTGTCGAGTACGGTCAGGTCAAGTCCAAGTTGGGTAGCGAGT
TGACAGTTTATGCGGCTGAATGTTGGGAGGATTTTTTCTCTCGGGTCAATAGAGCCATGCAGCTAATCCAACCGCTGGTC
TTTCTCTTTGTGGCCTTAATGGTCGTTCTCATCTACGCAGCCATGTTGCTGCCGATTTATCAAAATATGGAGTTGTAA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(33-150)

Type II secretion system (T2SS), protein F (T2SSF)

(218-338)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYB Streptococcus gordonii str. Challis substr. CH1

63.743

99.13

0.632
  comGB/cglB Streptococcus mitis NCTC 12261

60.896

97.101

0.591
  comYB Streptococcus mutans UA140

59.531

98.841

0.588
  comYB Streptococcus mutans UA159

59.531

98.841

0.588
  comGB/cglB Streptococcus mitis SK321

60.597

97.101

0.588
  comGB/cglB Streptococcus pneumoniae Rx1

60.299

97.101

0.586
  comGB/cglB Streptococcus pneumoniae D39

60.299

97.101

0.586
  comGB/cglB Streptococcus pneumoniae R6

60.299

97.101

0.586
  comGB/cglB Streptococcus pneumoniae TIGR4

60.299

97.101

0.586
  comGB Lactococcus lactis subsp. cremoris KW2

50.445

97.681

0.493