Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpX   Type   Regulator
Locus tag   NLY75_RS05755 Genome accession   NZ_CP100432
Coordinates   1143884..1145110 (-) Length   408 a.a.
NCBI ID   WP_002934974.1    Uniprot ID   G7SE29
Organism   Streptococcus suis T15     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1138884..1150110
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NLY75_RS11355 - 1139203..1139430 (-) 228 WP_226315859.1 excalibur calcium-binding domain-containing protein -
  NLY75_RS05730 (NLY75_05730) - 1139446..1140510 (-) 1065 WP_023370392.1 hypothetical protein -
  NLY75_RS05735 (NLY75_05735) - 1140645..1140827 (+) 183 WP_002934978.1 4-oxalocrotonate tautomerase -
  NLY75_RS05740 (NLY75_05740) lepA 1140877..1142709 (-) 1833 WP_023370394.1 translation elongation factor 4 -
  NLY75_RS05745 (NLY75_05745) ndk 1142805..1143218 (-) 414 WP_023370396.1 nucleoside-diphosphate kinase -
  NLY75_RS05750 (NLY75_05750) yihA 1143241..1143828 (-) 588 WP_014638915.1 ribosome biogenesis GTP-binding protein YihA/YsxC -
  NLY75_RS05755 (NLY75_05755) clpX 1143884..1145110 (-) 1227 WP_002934974.1 ATP-dependent Clp protease ATP-binding subunit ClpX Regulator
  NLY75_RS05760 (NLY75_05760) - 1145308..1145820 (-) 513 WP_023370398.1 dihydrofolate reductase -
  NLY75_RS05765 (NLY75_05765) - 1146106..1146945 (-) 840 WP_002934970.1 thymidylate synthase -
  NLY75_RS05770 (NLY75_05770) - 1146998..1147300 (-) 303 WP_023370400.1 hypothetical protein -
  NLY75_RS05775 (NLY75_05775) - 1147312..1147590 (-) 279 WP_012775087.1 hypothetical protein -
  NLY75_RS05780 (NLY75_05780) - 1147717..1148676 (-) 960 WP_023370402.1 ROK family glucokinase -
  NLY75_RS05785 (NLY75_05785) - 1148772..1149107 (-) 336 WP_023370404.1 hypothetical protein -

Sequence

Protein


Download         Length: 408 a.a.        Molecular weight: 45318.84 Da        Isoelectric Point: 4.6382

>NTDB_id=705322 NLY75_RS05755 WP_002934974.1 1143884..1145110(-) (clpX) [Streptococcus suis T15]
MAVKHTHELIYCSFCGKNQEEVKKIIAGNNVFICNECVELAQEIIREELAEEVLTDLADTPKPQELLNILNNYVIGQDRA
KRALAVAVYNHYKRINFQDSRDENDVDLQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATALTEAGYVGEDVENIL
LKLLQAADFNIDRAERGIIYVDEIDKIAKKGENVSITRDVSGEGVQQALLKIIEGTVASVPPQGGRKHPNQEMIHVDTKN
ILFIVGGAFDGIEEIVKQRLGEKIIGFGHNNRAIDEKESYMQHIIADDIQKFGIIPELIGRLPVFAALDQLTTEDLVRIL
TEPKNALVKQYQTLLSYDDVELDFDEDALLAIAEKAIERKTGARGLRSIIEETMLDVMFEVPGQDNVKRVRVTKAAVDGK
EKPLLETA

Nucleotide


Download         Length: 1227 bp        

>NTDB_id=705322 NLY75_RS05755 WP_002934974.1 1143884..1145110(-) (clpX) [Streptococcus suis T15]
ATGGCTGTTAAGCATACACATGAGCTAATATATTGCTCATTTTGCGGAAAAAATCAAGAAGAAGTTAAAAAAATTATCGC
AGGAAACAATGTCTTCATTTGTAATGAGTGCGTGGAACTAGCACAGGAAATCATTCGTGAGGAACTGGCAGAAGAAGTTT
TGACAGACTTGGCCGATACGCCAAAGCCACAAGAATTACTCAATATTCTGAACAACTACGTCATCGGACAGGATCGTGCA
AAACGTGCTTTAGCAGTAGCCGTTTACAACCACTACAAACGTATCAATTTCCAAGATAGCCGTGATGAGAACGATGTTGA
TTTGCAAAAATCAAATATCCTTATGATTGGCCCGACTGGTTCAGGAAAAACCTTCCTAGCTCAGACCTTGGCTAAAAGTT
TGAATGTCCCGTTTGCTATTGCCGATGCGACCGCTCTTACTGAGGCGGGTTATGTTGGTGAAGACGTAGAAAATATCCTC
CTCAAACTTTTGCAGGCTGCAGACTTTAACATTGACCGTGCAGAAAGAGGAATTATCTATGTGGATGAAATTGATAAAAT
TGCCAAAAAAGGTGAAAATGTGTCCATTACCCGCGATGTATCTGGTGAAGGTGTCCAGCAAGCTCTCCTAAAAATTATCG
AGGGAACTGTGGCCAGCGTACCACCACAAGGCGGACGCAAACATCCAAACCAAGAAATGATTCACGTGGACACCAAAAAT
ATCCTGTTTATCGTTGGCGGTGCATTTGATGGTATCGAAGAAATCGTCAAGCAGCGTCTCGGTGAAAAAATCATCGGTTT
TGGTCATAATAATCGTGCTATTGATGAAAAAGAATCATACATGCAACATATCATTGCAGACGATATTCAAAAATTCGGCA
TCATTCCAGAGTTGATTGGTCGCTTGCCTGTATTCGCAGCTTTGGACCAATTGACAACAGAGGATTTGGTACGCATTTTG
ACGGAACCGAAGAATGCTCTGGTAAAACAATACCAGACACTCTTGTCTTATGATGACGTGGAGCTTGACTTTGATGAGGA
CGCCTTGTTAGCAATTGCAGAAAAAGCAATTGAACGTAAAACTGGTGCTCGTGGACTTCGCTCCATCATTGAAGAAACGA
TGTTGGATGTCATGTTTGAGGTGCCAGGTCAAGATAACGTTAAACGCGTTCGTGTAACAAAAGCAGCAGTAGACGGTAAA
GAAAAGCCTTTACTAGAAACTGCATAA

Domains

Predicted by InterproScan.

ClpX C4-type zinc finger (zf-C4_ClpX)

(11-47)

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(311-389)

AAA domain (Cdc48 subfamily) (AAA_2)

(109-304)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB G7SE29

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpX Streptococcus mutans UA159

83.13

100

0.833
  clpX Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

58.209

98.529

0.574