Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpX   Type   Regulator
Locus tag   NLY77_RS04680 Genome accession   NZ_CP100431
Coordinates   925079..926305 (+) Length   408 a.a.
NCBI ID   WP_002934974.1    Uniprot ID   G7SE29
Organism   Streptococcus suis strain 1521251     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 920079..931305
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NLY77_RS04650 (NLY77_04650) - 921193..921528 (+) 336 WP_024394321.1 hypothetical protein -
  NLY77_RS04655 (NLY77_04655) - 921624..922583 (+) 960 WP_024394320.1 ROK family glucokinase -
  NLY77_RS04660 (NLY77_04660) - 922709..922987 (+) 279 WP_024394319.1 hypothetical protein -
  NLY77_RS04665 (NLY77_04665) - 922999..923301 (+) 303 WP_024394318.1 hypothetical protein -
  NLY77_RS04670 (NLY77_04670) - 923354..924193 (+) 840 WP_024394317.1 thymidylate synthase -
  NLY77_RS04675 (NLY77_04675) - 924369..924881 (+) 513 WP_024394316.1 dihydrofolate reductase -
  NLY77_RS04680 (NLY77_04680) clpX 925079..926305 (+) 1227 WP_002934974.1 ATP-dependent Clp protease ATP-binding subunit ClpX Regulator
  NLY77_RS04685 (NLY77_04685) yihA 926361..926948 (+) 588 WP_014638915.1 ribosome biogenesis GTP-binding protein YihA/YsxC -
  NLY77_RS04690 (NLY77_04690) ndk 926971..927384 (+) 414 WP_024394314.1 nucleoside-diphosphate kinase -
  NLY77_RS04695 (NLY77_04695) lepA 927480..929312 (+) 1833 WP_002943192.1 translation elongation factor 4 -
  NLY77_RS04700 (NLY77_04700) - 929362..929544 (-) 183 WP_002934978.1 4-oxalocrotonate tautomerase -
  NLY77_RS04705 (NLY77_04705) - 929679..930986 (+) 1308 WP_002934980.1 excalibur calcium-binding domain-containing protein -
  NLY77_RS04710 (NLY77_04710) - 931048..931272 (+) 225 WP_002934981.1 hypothetical protein -

Sequence

Protein


Download         Length: 408 a.a.        Molecular weight: 45318.84 Da        Isoelectric Point: 4.6382

>NTDB_id=705257 NLY77_RS04680 WP_002934974.1 925079..926305(+) (clpX) [Streptococcus suis strain 1521251]
MAVKHTHELIYCSFCGKNQEEVKKIIAGNNVFICNECVELAQEIIREELAEEVLTDLADTPKPQELLNILNNYVIGQDRA
KRALAVAVYNHYKRINFQDSRDENDVDLQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATALTEAGYVGEDVENIL
LKLLQAADFNIDRAERGIIYVDEIDKIAKKGENVSITRDVSGEGVQQALLKIIEGTVASVPPQGGRKHPNQEMIHVDTKN
ILFIVGGAFDGIEEIVKQRLGEKIIGFGHNNRAIDEKESYMQHIIADDIQKFGIIPELIGRLPVFAALDQLTTEDLVRIL
TEPKNALVKQYQTLLSYDDVELDFDEDALLAIAEKAIERKTGARGLRSIIEETMLDVMFEVPGQDNVKRVRVTKAAVDGK
EKPLLETA

Nucleotide


Download         Length: 1227 bp        

>NTDB_id=705257 NLY77_RS04680 WP_002934974.1 925079..926305(+) (clpX) [Streptococcus suis strain 1521251]
ATGGCTGTTAAGCATACACATGAGCTAATCTATTGCTCATTTTGCGGAAAAAATCAAGAAGAAGTTAAAAAAATTATCGC
AGGGAACAATGTCTTCATTTGTAATGAGTGCGTGGAACTAGCACAGGAAATCATTCGTGAGGAACTGGCAGAAGAAGTTT
TGACAGACTTGGCCGATACGCCAAAGCCACAAGAATTACTCAATATCCTGAACAACTACGTCATCGGACAGGATCGTGCA
AAACGTGCTTTAGCAGTAGCCGTTTACAACCACTACAAACGTATCAATTTCCAAGATAGCCGTGATGAGAACGATGTTGA
TTTGCAAAAATCAAATATCCTCATGATTGGCCCGACTGGTTCAGGAAAAACCTTCCTAGCTCAGACCTTGGCTAAAAGTT
TGAATGTCCCGTTTGCTATTGCTGATGCGACTGCTCTTACTGAGGCGGGTTATGTTGGTGAAGACGTAGAAAATATCCTC
CTCAAACTTTTGCAGGCTGCAGACTTTAACATCGACCGTGCAGAAAGAGGAATTATCTATGTGGATGAAATTGATAAAAT
TGCCAAAAAAGGTGAAAATGTGTCCATTACCCGCGATGTATCTGGTGAAGGTGTCCAGCAAGCTCTCCTAAAAATTATCG
AGGGAACTGTGGCCAGCGTACCACCACAAGGCGGACGCAAACATCCAAACCAAGAAATGATTCACGTGGATACCAAAAAT
ATCCTGTTTATCGTTGGCGGTGCATTTGATGGTATCGAAGAAATCGTCAAGCAGCGTCTCGGTGAAAAAATCATCGGTTT
TGGTCATAATAATCGTGCTATTGATGAAAAAGAATCATACATGCAACATATCATTGCAGACGATATTCAAAAATTCGGTA
TCATTCCAGAGTTGATTGGTCGCTTGCCTGTATTTGCAGCTTTGGACCAATTGACAACAGAGGATTTGGTACGCATTTTG
ACGGAACCGAAGAATGCTCTTGTAAAACAATACCAGACACTCTTGTCTTATGATGACGTGGAGCTTGACTTTGATGAGGA
CGCCTTGTTAGCAATTGCAGAAAAGGCAATTGAACGTAAGACTGGTGCTCGTGGACTTCGTTCCATCATTGAAGAAACGA
TGTTGGATGTCATGTTTGAGGTGCCAGGCCAAGATAACGTTAAACGCGTTCGTGTAACAAAAGCAGCAGTAGACGGTAAG
GAAAAGCCTTTACTAGAAACTGCATAA

Domains

Predicted by InterproScan.

ClpX C4-type zinc finger (zf-C4_ClpX)

(11-47)

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(311-389)

AAA domain (Cdc48 subfamily) (AAA_2)

(109-304)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB G7SE29

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpX Streptococcus mutans UA159

83.13

100

0.833
  clpX Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

58.209

98.529

0.574