Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   NLY76_RS08130 Genome accession   NZ_CP100430
Coordinates   1667197..1667886 (-) Length   229 a.a.
NCBI ID   WP_002942700.1    Uniprot ID   A0A126UNE5
Organism   Streptococcus suis strain LSS42     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1662197..1672886
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NLY76_RS08105 (NLY76_08105) - 1662512..1663225 (-) 714 WP_024390114.1 NADPH-dependent oxidoreductase -
  NLY76_RS08110 (NLY76_08110) dnaI 1663222..1664121 (-) 900 WP_044757363.1 primosomal protein DnaI -
  NLY76_RS08115 (NLY76_08115) - 1664121..1665272 (-) 1152 WP_024390115.1 replication initiation/membrane attachment protein -
  NLY76_RS08120 (NLY76_08120) nrdR 1665259..1665750 (-) 492 WP_002938341.1 transcriptional regulator NrdR -
  NLY76_RS08125 (NLY76_08125) - 1665822..1666952 (-) 1131 WP_012027644.1 AI-2E family transporter -
  NLY76_RS08130 (NLY76_08130) covR 1667197..1667886 (-) 690 WP_002942700.1 DNA-binding response regulator Regulator
  NLY76_RS08135 (NLY76_08135) gndA 1667968..1669395 (-) 1428 WP_002942698.1 NADP-dependent phosphogluconate dehydrogenase -
  NLY76_RS08140 (NLY76_08140) - 1669492..1670031 (-) 540 WP_014736258.1 DUF177 domain-containing protein -
  NLY76_RS08145 (NLY76_08145) trxB 1670041..1670958 (-) 918 WP_029751717.1 thioredoxin-disulfide reductase -
  NLY76_RS08150 (NLY76_08150) - 1670973..1671197 (-) 225 WP_044770125.1 DUF4059 family protein -
  NLY76_RS08155 (NLY76_08155) - 1671215..1672558 (-) 1344 WP_044770126.1 DEAD/DEAH box helicase -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26225.11 Da        Isoelectric Point: 5.3968

>NTDB_id=705221 NLY76_RS08130 WP_002942700.1 1667197..1667886(-) (covR) [Streptococcus suis strain LSS42]
MAKKILIAGKERNLSHFVSMELQKKDYLVDYASTGKEAMSLAHETDFDLILMSFQLSDMSSKELAAELLAIKPATVMIVV
VEPTEVSQYGEEVLSYAVSYVVKPFVISDLVEQISAIFRGRDFIDNNCKQVHMHAAYRDLKVDFQNRTVTRGDELINLTR
REYDLLATLMNSPEPVSREQLLERVWKYEAASETNVVDVYIRYLRGKLDLPHQDSYIKTVRGVGYAMRD

Nucleotide


Download         Length: 690 bp        

>NTDB_id=705221 NLY76_RS08130 WP_002942700.1 1667197..1667886(-) (covR) [Streptococcus suis strain LSS42]
ATGGCTAAGAAAATTTTGATTGCTGGTAAAGAACGCAATCTCTCGCATTTTGTTTCCATGGAATTGCAGAAAAAAGACTA
TCTTGTTGATTATGCATCGACAGGGAAAGAGGCTATGTCCTTGGCACATGAAACGGATTTTGACTTGATTCTGATGAGTT
TTCAGCTTTCAGACATGTCCAGCAAGGAATTGGCTGCAGAACTATTAGCGATAAAACCAGCCACGGTCATGATTGTGGTA
GTTGAGCCGACAGAAGTTAGTCAATATGGGGAAGAAGTCCTCTCTTATGCTGTTTCCTACGTAGTGAAGCCCTTTGTCAT
CAGTGATTTAGTGGAGCAAATCTCTGCGATTTTTCGTGGTCGTGATTTTATTGACAATAACTGTAAACAGGTTCACATGC
ATGCGGCCTATCGTGATTTGAAGGTTGATTTTCAAAATCGAACAGTGACTCGAGGTGATGAATTGATTAATTTGACCCGC
CGAGAGTATGATCTGTTGGCGACCTTAATGAACAGCCCAGAGCCTGTTAGTCGAGAACAACTTCTTGAGCGTGTTTGGAA
ATATGAAGCGGCTTCTGAGACCAATGTCGTCGATGTATATATTCGCTATCTACGTGGTAAACTGGATTTGCCACATCAAG
ATTCATATATAAAAACAGTTCGTGGTGTCGGATATGCCATGCGCGATTGA

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(155-227)

Response regulator receiver domain (Response_reg)

(5-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A126UNE5

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

47.619

100

0.48
  covR Lactococcus lactis subsp. lactis strain DGCC12653

41.949

100

0.432