Detailed information    

insolico Bioinformatically predicted

Overview

Name   mutX   Type   Machinery gene
Locus tag   H7675_RS05470 Genome accession   NZ_AP023389
Coordinates   1082594..1083070 (-) Length   158 a.a.
NCBI ID   WP_002984880.1    Uniprot ID   A0A0H2UU18
Organism   Streptococcus pyogenes strain KUN-0012590     
Function   DNA mismatch repair (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1077594..1088070
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  H7675_RS05455 (KUN2590_10330) fbp54 1078407..1080059 (+) 1653 WP_184004525.1 Rqc2 family fibronectin-binding protein Fbp54 -
  H7675_RS05460 (KUN2590_10340) - 1080118..1081365 (-) 1248 WP_002984878.1 tetratricopeptide repeat protein -
  H7675_RS05465 (KUN2590_10350) - 1081355..1082536 (-) 1182 WP_031488330.1 AI-2E family transporter -
  H7675_RS05470 (KUN2590_10360) mutX 1082594..1083070 (-) 477 WP_002984880.1 NUDIX hydrolase Machinery gene
  H7675_RS05475 (KUN2590_10370) rfbB 1083291..1084331 (-) 1041 WP_010922196.1 dTDP-glucose 4,6-dehydratase -
  H7675_RS05480 (KUN2590_10380) - 1084575..1085168 (-) 594 WP_002990099.1 dTDP-4-dehydrorhamnose 3,5-epimerase family protein -
  H7675_RS05485 (KUN2590_10390) rfbA 1085168..1086037 (-) 870 WP_014407521.1 glucose-1-phosphate thymidylyltransferase RfbA -
  H7675_RS05490 (KUN2590_10400) - 1086095..1087201 (-) 1107 WP_063510231.1 NAD(P)/FAD-dependent oxidoreductase -
  H7675_RS05495 (KUN2590_10410) - 1087241..1088029 (-) 789 WP_031488333.1 Nif3-like dinuclear metal center hexameric protein -

Sequence

Protein


Download         Length: 158 a.a.        Molecular weight: 18462.68 Da        Isoelectric Point: 4.3268

>NTDB_id=70475 H7675_RS05470 WP_002984880.1 1082594..1083070(-) (mutX) [Streptococcus pyogenes strain KUN-0012590]
MTQLATICYIDNGDSLLLLHRNKKENDVHKGKWISVGGKLEAGETPDECARREILEETHLTVTEMAFKGIITFPEFTPGH
DWYTYVFKVTGFEGDLISDEESREGTLEWVPYDQVLEKPTWEGDYDIFKWILEDRPFFSAKFTYDQNNQLMDKSVTFY

Nucleotide


Download         Length: 477 bp        

>NTDB_id=70475 H7675_RS05470 WP_002984880.1 1082594..1083070(-) (mutX) [Streptococcus pyogenes strain KUN-0012590]
ATGACTCAATTAGCAACCATTTGTTACATTGATAATGGCGATTCTTTGCTATTATTACACCGCAATAAAAAAGAAAATGA
TGTCCACAAAGGCAAGTGGATTTCAGTTGGGGGTAAGCTCGAGGCTGGTGAGACCCCAGATGAGTGTGCCCGTCGTGAGA
TTTTAGAGGAAACCCATTTGACTGTTACAGAGATGGCCTTTAAAGGAATCATTACTTTTCCAGAATTTACCCCTGGTCAT
GACTGGTATACCTATGTTTTTAAAGTAACAGGATTTGAAGGAGACCTCATTTCAGATGAAGAGTCACGAGAAGGAACCTT
GGAATGGGTACCTTACGATCAAGTGTTGGAAAAGCCAACTTGGGAAGGTGATTATGACATTTTTAAATGGATTTTAGAAG
ACCGTCCTTTTTTCTCTGCCAAATTTACCTATGACCAAAACAACCAACTCATGGATAAATCTGTGACCTTTTATTGA

Domains

Predicted by InterProScan.

NUDIX domain (NUDIX)

(2-130)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0H2UU18

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mutX Streptococcus pneumoniae R6

70.253

100

0.703

Multiple sequence alignment