Detailed information NTG0704675

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: NKZ79_RS08805
• Genome accession: NZ_CP100340
• Coordinates: 1751710..1752759 (-)
• Length: 349 a.a.
• NCBI ID: WP_012775295.1
• Uniprot ID: A0A2K1T047
• Organism: Streptococcus suis strain STC78
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 1746710..1757759

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
NKZ79_RS08785 (NKZ79_08785)	trpB	1747026..1748201 (-)	1176	WP_204101559.1	tryptophan synthase subunit beta	-
NKZ79_RS08790 (NKZ79_08790)	-	1749236..1749763 (-)	528	WP_002942846.1	VanZ family protein	-
NKZ79_RS08795 (NKZ79_08795)	rlmN	1749760..1750872 (-)	1113	WP_012028433.1	23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN	-
NKZ79_RS08800 (NKZ79_08800)	-	1750881..1751522 (-)	642	WP_014638483.1	YutD-like domain-containing protein	-
NKZ79_RS08805 (NKZ79_08805)	sepM	1751710..1752759 (-)	1050	WP_012775295.1	SepM family pheromone-processing serine protease	Regulator
NKZ79_RS08810 (NKZ79_08810)	coaD	1752746..1753234 (-)	489	WP_015647233.1	pantetheine-phosphate adenylyltransferase	-
NKZ79_RS08815 (NKZ79_08815)	rsmD	1753224..1753763 (-)	540	WP_024388284.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
NKZ79_RS08820 (NKZ79_08820)	-	1754070..1754792 (-)	723	WP_044684680.1	hypothetical protein	-
NKZ79_RS08825 (NKZ79_08825)	-	1754849..1755235 (-)	387	WP_004194735.1	rhodanese-like domain-containing protein	-
NKZ79_RS08830 (NKZ79_08830)	-	1755235..1755453 (-)	219	WP_041179287.1	YqgQ family protein	-
NKZ79_RS08835 (NKZ79_08835)	-	1755761..1756363 (-)	603	WP_015647237.1	response regulator transcription factor	-
NKZ79_RS08840 (NKZ79_08840)	-	1756360..1757454 (-)	1095	WP_044684682.1	sensor histidine kinase	-

Sequence

Protein

• Length: 349 a.a.
• Molecular weight: 37761.83 Da
• Isoelectric Point: 4.6112

>NTDB_id=704675 NKZ79_RS08805 WP_012775295.1 1751710..1752759(-) (sepM) [Streptococcus suis strain STC78]
MKKNRKLTLIASIVLGTLLIWFAVFVRLPYYLESPGGAADIRQVLTVNNQIDQEDGSYNFTYVSVQQATALQLFAAQFDP
YTTVRSSEEMTGGADNEEYFRIARFYMETSQNMAKYQGLTLAGKEVNLDFFGVYVLALTDDSTFKKVLNIADTVVSINGK
TFESSPDLIKYVSGLEVGSDVTVGYISAGQEKSADGKIIKLSNGKNGIGITLVDHTEVQSSIPIDFQTGDIGGPSAGLMF
TLAIYTQLAEPDLRDGRIIAGTGTIEQDGKVGDIGGADKKVISAAKSGASIFFVPNNPVDVEVLKKNPKAKTNYEEAKEA
AEKAGLDIEVVPVKTVQEAIDYLKKTKGE

Nucleotide

• Length: 1050 bp

>NTDB_id=704675 NKZ79_RS08805 WP_012775295.1 1751710..1752759(-) (sepM) [Streptococcus suis strain STC78]
ATGAAGAAAAATAGGAAGTTAACCTTAATTGCATCTATTGTTTTAGGAACTCTTTTGATTTGGTTTGCCGTTTTTGTTCG
TCTGCCTTATTATTTGGAAAGTCCAGGTGGAGCTGCCGATATTCGTCAGGTACTAACGGTGAACAATCAAATAGACCAAG
AGGATGGCTCTTACAACTTCACCTATGTATCAGTCCAACAAGCTACAGCTTTACAACTATTCGCTGCTCAGTTTGATCCC
TATACGACAGTTCGTTCCTCTGAAGAGATGACAGGAGGGGCCGACAATGAGGAGTATTTCCGTATAGCACGGTTTTACAT
GGAAACTTCGCAAAATATGGCGAAGTATCAAGGATTGACCTTGGCAGGAAAAGAAGTCAATCTTGATTTCTTTGGTGTCT
ATGTGCTTGCCTTGACGGATGATTCAACCTTTAAAAAAGTTCTTAATATTGCCGACACTGTTGTGAGTATCAATGGAAAA
ACATTTGAGTCTTCTCCTGATTTGATTAAATATGTGAGTGGCTTGGAGGTTGGAAGTGATGTAACAGTTGGTTATATTAG
CGCTGGTCAGGAAAAATCTGCGGACGGTAAGATTATCAAATTGTCTAATGGCAAAAACGGAATAGGCATCACTCTCGTAG
ATCATACAGAGGTTCAAAGTTCGATTCCGATTGATTTCCAAACAGGAGATATTGGTGGTCCAAGTGCTGGTCTGATGTTT
ACACTTGCCATCTATACTCAACTCGCAGAGCCTGACTTACGTGATGGTCGGATTATTGCTGGTACGGGGACTATCGAGCA
GGATGGAAAAGTAGGTGACATTGGTGGGGCTGATAAGAAGGTCATTTCGGCAGCTAAGTCTGGTGCAAGTATCTTTTTTG
TACCAAACAATCCAGTTGATGTAGAAGTTTTGAAGAAAAACCCAAAGGCTAAAACGAACTATGAAGAAGCTAAGGAAGCA
GCCGAGAAAGCAGGTCTAGATATTGAGGTAGTTCCTGTGAAAACTGTTCAAGAGGCTATTGATTATTTGAAGAAAACAAA
GGGCGAGTAA

Domains

Predicted by InterproScan.

• PDZ domain (PDZ_2) (132-195)

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (232-315)

3D structure

• AlphaFold DB: A0A2K1T047

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	60.807	99.427	0.605