Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   NKZ66_RS09040 Genome accession   NZ_CP100336
Coordinates   1791644..1792333 (-) Length   229 a.a.
NCBI ID   WP_012027645.1    Uniprot ID   -
Organism   Streptococcus suis strain STC81     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1786644..1797333
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NKZ66_RS09015 (NKZ66_09015) - 1787115..1787827 (-) 713 Protein_1740 nitroreductase family protein -
  NKZ66_RS09020 (NKZ66_09020) dnaI 1787824..1788723 (-) 900 WP_043026135.1 primosomal protein DnaI -
  NKZ66_RS09025 (NKZ66_09025) - 1788723..1789874 (-) 1152 WP_105152114.1 replication initiation/membrane attachment protein -
  NKZ66_RS09030 (NKZ66_09030) nrdR 1789861..1790352 (-) 492 WP_002938341.1 transcriptional regulator NrdR -
  NKZ66_RS09035 (NKZ66_09035) - 1790424..1791554 (-) 1131 WP_043026138.1 AI-2E family transporter -
  NKZ66_RS09040 (NKZ66_09040) covR 1791644..1792333 (-) 690 WP_012027645.1 DNA-binding response regulator Regulator
  NKZ66_RS09045 (NKZ66_09045) gndA 1792415..1793842 (-) 1428 WP_204101564.1 NADP-dependent phosphogluconate dehydrogenase -
  NKZ66_RS09050 (NKZ66_09050) - 1793930..1794469 (-) 540 WP_024417740.1 DUF177 domain-containing protein -
  NKZ66_RS09055 (NKZ66_09055) trxB 1794479..1795396 (-) 918 WP_002942687.1 thioredoxin-disulfide reductase -
  NKZ66_RS09060 (NKZ66_09060) - 1795410..1795634 (-) 225 WP_002936682.1 DUF4059 family protein -
  NKZ66_RS09065 (NKZ66_09065) - 1795652..1796995 (-) 1344 WP_105095192.1 DEAD/DEAH box helicase -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26255.14 Da        Isoelectric Point: 5.3968

>NTDB_id=704566 NKZ66_RS09040 WP_012027645.1 1791644..1792333(-) (covR) [Streptococcus suis strain STC81]
MAKKILIAGKERNLSHFVSMELQKKDYLVDYASTGKEAMSLAHETDFDLILMSFQLSDMSSKELATELLAIKPATVMIVV
VEPTEVSQYGEEVLSYAVSYVVKPFVISDLVEQISAIFRGRDFIDNNCKQVHMHAAYRDLKVDFQNRTVTRGDELINLTR
REYDLLATLMNSPEPVSREQLLERVWKYEAASETNVVDVYIRYLRGKLDLPHQDSYIKTVRGVGYAMRD

Nucleotide


Download         Length: 690 bp        

>NTDB_id=704566 NKZ66_RS09040 WP_012027645.1 1791644..1792333(-) (covR) [Streptococcus suis strain STC81]
ATGGCTAAGAAAATTTTGATTGCTGGTAAAGAACGCAATCTCTCGCATTTTGTTTCCATGGAATTGCAGAAAAAAGACTA
TCTTGTTGATTATGCATCGACAGGGAAAGAGGCTATGTCCTTGGCACATGAAACGGATTTTGACTTGATTCTGATGAGTT
TTCAGCTTTCAGACATGTCCAGCAAGGAATTGGCTACAGAACTATTAGCGATAAAACCAGCCACGGTCATGATTGTGGTA
GTTGAGCCGACAGAAGTTAGTCAATATGGGGAAGAAGTCCTCTCTTATGCTGTTTCCTACGTAGTGAAGCCCTTTGTCAT
CAGTGATTTAGTGGAGCAAATCTCTGCGATTTTTCGTGGTCGTGACTTTATTGACAATAACTGTAAACAGGTTCACATGC
ATGCGGCCTATCGTGATTTGAAGGTTGATTTTCAAAATCGAACAGTGACTCGAGGTGATGAATTGATTAATTTGACCCGC
CGAGAGTATGATCTGTTGGCGACCTTAATGAATAGCCCAGAGCCTGTTAGTAGAGAACAACTTCTTGAGCGTGTTTGGAA
ATATGAAGCGGCTTCTGAGACCAATGTCGTCGATGTATATATTCGCTATCTACGTGGTAAACTGGATTTGCCACATCAAG
ATTCATATATAAAAACAGTTCGTGGTGTCGGATATGCCATGCGCGATTGA

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(155-227)

Response regulator receiver domain (Response_reg)

(5-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

47.619

100

0.48
  covR Lactococcus lactis subsp. lactis strain DGCC12653

41.949

100

0.432