Detailed information    

insolico Bioinformatically predicted

Overview

Name   micB   Type   Regulator
Locus tag   NKZ66_RS07375 Genome accession   NZ_CP100336
Coordinates   1490468..1491817 (-) Length   449 a.a.
NCBI ID   WP_044670912.1    Uniprot ID   A0A123U4C9
Organism   Streptococcus suis strain STC81     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1485468..1496817
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NKZ66_RS07360 (NKZ66_07360) pbp2b 1485851..1487923 (-) 2073 WP_024376693.1 penicillin-binding protein PBP2B -
  NKZ66_RS07365 (NKZ66_07365) vga(F) 1488015..1489400 (-) 1386 WP_254369355.1 ABC-F type ribosomal protection protein Vga(F) -
  NKZ66_RS07370 (NKZ66_07370) vicX 1489658..1490461 (-) 804 WP_099807080.1 MBL fold metallo-hydrolase Regulator
  NKZ66_RS07375 (NKZ66_07375) micB 1490468..1491817 (-) 1350 WP_044670912.1 cell wall metabolism sensor histidine kinase VicK Regulator
  NKZ66_RS07380 (NKZ66_07380) micA 1491810..1492514 (-) 705 WP_204101676.1 response regulator YycF Regulator
  NKZ66_RS07385 (NKZ66_07385) - 1492708..1493469 (+) 762 WP_002935839.1 amino acid ABC transporter ATP-binding protein -
  NKZ66_RS07390 (NKZ66_07390) - 1493480..1494319 (+) 840 WP_002935837.1 transporter substrate-binding domain-containing protein -
  NKZ66_RS07395 (NKZ66_07395) - 1494334..1495032 (+) 699 WP_002935835.1 amino acid ABC transporter permease -
  NKZ66_RS07400 (NKZ66_07400) - 1495047..1495706 (+) 660 WP_002935828.1 amino acid ABC transporter permease -

Sequence

Protein


Download         Length: 449 a.a.        Molecular weight: 51066.10 Da        Isoelectric Point: 4.5202

>NTDB_id=704559 NKZ66_RS07375 WP_044670912.1 1490468..1491817(-) (micB) [Streptococcus suis strain STC81]
MINQLRYLMTTAEFWFVVILIGFLIALTVLLIENYRDNKQIKQLNQKVNALIEGNYADVLDMRGSPEITDMANSLNDLSE
VIRLTHDNLEQEKTRLTSILSYMSDGVIATDRIGRIIMINDMAQKQLGLSNQKQEQYHLLEVLDLSDRYTLRDLLAQTPE
IVIDHTNENEEFLTLRANFATIRSESGLISGLVVVLHDMTEQAKEERERRLFVSNVSHELRTPLTSVKSYLEALDEGALT
ESVAPSFVKVSLDETNRMMRMITDLLSLSRIDNQVGQIDVELINFTAFVTFILNRFDQMKNADSDKVYTIVRDYQISPIW
VEIDTDKMTQVLDNILNNAIKYSPDGGTITFSMKTTDSQLIVSVSDEGLGIPKADLPRIFDRFYRVDKARSRAQGGTGLG
LAIAKEIVKQHKGFIWAKSEYGHGSTFTIVLPYSKDIALDEWDDSDEEE

Nucleotide


Download         Length: 1350 bp        

>NTDB_id=704559 NKZ66_RS07375 WP_044670912.1 1490468..1491817(-) (micB) [Streptococcus suis strain STC81]
ATGATTAATCAATTACGTTATTTAATGACCACGGCAGAATTTTGGTTTGTTGTCATTTTGATTGGCTTTCTAATTGCTCT
GACGGTCCTTTTGATTGAAAACTATCGGGATAATAAGCAAATTAAACAACTCAATCAAAAAGTCAATGCCTTAATTGAGG
GGAATTATGCAGATGTGTTAGACATGAGGGGAAGTCCTGAAATCACAGACATGGCGAATTCTCTTAATGATCTGTCCGAG
GTCATCCGTTTAACTCATGATAATTTAGAACAAGAAAAGACTCGTCTGACTTCCATCCTGTCCTATATGAGTGACGGTGT
TATTGCTACAGACCGTATCGGACGGATCATCATGATTAACGATATGGCCCAGAAACAGTTGGGACTTTCTAACCAAAAGC
AGGAGCAGTATCACCTGCTAGAGGTTTTAGATTTATCAGACCGTTATACATTGAGAGATTTGTTGGCTCAGACACCTGAG
ATTGTGATTGATCACACCAATGAAAACGAAGAATTTTTGACTTTACGCGCTAATTTTGCCACGATTCGTAGTGAGAGTGG
TCTGATTTCTGGCTTGGTTGTCGTCTTACATGATATGACCGAGCAGGCCAAGGAAGAACGGGAACGTAGGCTGTTTGTGT
CAAATGTGAGTCATGAATTGCGTACGCCATTGACTTCCGTCAAATCCTATCTAGAGGCTCTGGATGAGGGAGCGCTGACG
GAGTCTGTTGCACCGAGTTTTGTTAAGGTATCCTTAGATGAGACCAACCGCATGATGCGGATGATTACAGACCTCCTAAG
CTTATCGCGTATTGATAATCAAGTTGGTCAGATAGATGTCGAACTGATAAACTTTACTGCTTTTGTGACCTTTATTCTTA
ACCGTTTTGACCAAATGAAAAATGCTGATTCTGATAAGGTCTATACGATTGTTCGTGACTATCAAATCAGTCCTATTTGG
GTTGAGATTGATACAGATAAGATGACTCAGGTTTTGGATAATATCTTAAATAATGCCATTAAATATTCGCCAGACGGTGG
GACAATTACCTTCAGCATGAAGACCACGGATAGCCAGTTGATTGTATCCGTCTCAGACGAAGGTCTGGGGATTCCGAAAG
CAGATTTACCTAGAATTTTTGACCGATTCTATCGCGTGGACAAGGCACGATCTCGTGCCCAAGGTGGTACAGGTCTTGGT
TTAGCTATTGCAAAAGAAATCGTAAAACAACATAAGGGCTTTATCTGGGCTAAAAGCGAATATGGTCATGGCTCAACGTT
TACAATTGTCTTGCCGTACAGCAAGGACATCGCACTAGATGAGTGGGATGATTCAGATGAGGAAGAATAG

Domains

Predicted by InterproScan.

His Kinase A (phospho-acceptor) domain (HisKA)

(209-273)

PAS fold (PAS)

(96-199)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(324-434)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A123U4C9

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  micB Streptococcus pneumoniae Cp1015

70.183

97.105

0.682
  vicK Streptococcus mutans UA159

70.72

89.755

0.635