Detailed information NTG0704555

Bioinformatically predicted

Overview

• Name: comEC/celB
• Type: Machinery gene
• Locus tag: NKZ66_RS06090
• Genome accession: NZ_CP100336
• Coordinates: 1212740..1214977 (-)
• Length: 745 a.a.
• NCBI ID: WP_044752722.1
• Uniprot ID: -
• Organism: Streptococcus suis strain STC81
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1207740..1219977

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
NKZ66_RS06060 (NKZ66_06060)	tmk	1207857..1208495 (-)	639	WP_002935358.1	dTMP kinase	-
NKZ66_RS06065 (NKZ66_06065)	-	1208670..1209536 (+)	867	WP_002935357.1	YitT family protein	-
NKZ66_RS06070 (NKZ66_06070)	-	1209573..1210844 (-)	1272	WP_002935355.1	toxic anion resistance protein	-
NKZ66_RS06075 (NKZ66_06075)	-	1210850..1211677 (-)	828	WP_024417275.1	hypothetical protein	-
NKZ66_RS06080 (NKZ66_06080)	-	1211770..1212426 (-)	657	WP_023370708.1	CBS domain-containing protein	-
NKZ66_RS06085 (NKZ66_06085)	-	1212609..1212731 (-)	123	Protein_1152	IS982 family transposase	-
NKZ66_RS06090 (NKZ66_06090)	comEC/celB	1212740..1214977 (-)	2238	WP_044752722.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
NKZ66_RS06095 (NKZ66_06095)	comEA/celA/cilE	1214961..1215623 (-)	663	WP_079394055.1	helix-hairpin-helix domain-containing protein	Machinery gene
NKZ66_RS06100 (NKZ66_06100)	-	1215693..1216439 (-)	747	WP_014735985.1	1-acyl-sn-glycerol-3-phosphate acyltransferase	-
NKZ66_RS06105 (NKZ66_06105)	-	1216586..1218031 (+)	1446	WP_172001200.1	UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L- lysine ligase	-
NKZ66_RS06110 (NKZ66_06110)	-	1218183..1218983 (+)	801	WP_172001201.1	ABC transporter ATP-binding protein	-
NKZ66_RS06115 (NKZ66_06115)	-	1218980..1219909 (+)	930	WP_172001202.1	ABC transporter substrate-binding protein	-

Sequence

Protein

• Length: 745 a.a.
• Molecular weight: 84145.26 Da
• Isoelectric Point: 7.3815

>NTDB_id=704555 NKZ66_RS06090 WP_044752722.1 1212740..1214977(-) (comEC/celB) [Streptococcus suis strain STC81]
MLRSIKLPCQPIHLALLAVAAYFVVRSFSLLTMGLLSLVLAVFGVRQGKAVFLRTLPLLALCGLFFGFQKLQWNRADQSA
PEQVTTVQVIPDTIEVNGDSLSFRGRADGQTYQVFYKLASQEEQTYFQELADLVQLEVEAEVSLPAGQRNFKGFDYQAYL
KTQGIYRTVKITVIKKIVPVQSRNVFDWLSSWRRQALVYIKTNFPAPMSHYMTGLLFGELDSDFDQMSDLYSSLGIIHLF
ALSGMQVGFFIDKFRWILLRLGLTKEAVDKLQIPFSIVYAGLTGFSVSVVRSLVQKILGNLGLRKLDNFAVTVFVCFLLL
PRFLLTAGGVLTFTYAFLLTVFDFEDLGQVKKAAVESLSISLGILPVLMIYFFAFQPLSILLTFVFSFVFDVLLLPGLSV
IFLLSPIIKITWVNGFFVLMEKIIVWVADLGLRPWILGKPSVVILILLLVCLFLLYDFHRKKKWLLGLSLVLALLFFITK
HPLENEVTVVDIGQGDSIFMRDMRGRTVLIDVGGRVDFAAKEAWQERSRQANAERTLIPYLHSRGVDRIDSLVLTHTDTD
HVGDVLEVAKQVHIGRIYVSPGSLTVPDFVATLKEINVPVHVVKVGDRLPIFDSYLEVLYPDGTGDGGNNDSIVLYGRLL
ETNFLFTGDLEQGELDLIETYPNLPVDVLKAGHHGSKGSSYPEFLDHIEAKIALISAGENNRYKHPHQETLDRFDSRDIQ
VYRTDQQGAIRFRGWKEWRIETVRR

Nucleotide

• Length: 2238 bp

>NTDB_id=704555 NKZ66_RS06090 WP_044752722.1 1212740..1214977(-) (comEC/celB) [Streptococcus suis strain STC81]
ATGTTACGGTCGATTAAGCTCCCCTGCCAGCCCATTCACCTGGCTCTTTTGGCGGTGGCAGCCTACTTTGTAGTCCGCTC
TTTTTCCCTCTTGACAATGGGCCTGCTCAGTTTGGTGTTAGCTGTCTTTGGTGTTCGGCAAGGTAAGGCAGTTTTCCTCA
GAACGCTGCCGCTTCTAGCCCTGTGTGGTCTCTTTTTCGGATTTCAAAAGCTTCAATGGAATCGAGCAGACCAGTCAGCC
CCAGAGCAAGTCACAACTGTTCAGGTCATTCCAGATACCATTGAAGTCAACGGGGACAGTCTGTCCTTTCGCGGTCGGGC
TGACGGACAAACCTATCAGGTTTTCTACAAATTAGCCAGTCAGGAGGAGCAGACTTATTTTCAAGAGCTGGCAGACCTGG
TCCAGCTAGAAGTGGAAGCAGAGGTCAGCCTGCCAGCTGGTCAGAGGAATTTCAAGGGCTTTGACTATCAGGCCTATCTG
AAAACACAGGGCATCTATCGGACAGTCAAGATTACGGTAATCAAGAAGATTGTCCCTGTCCAGTCTAGGAATGTTTTTGA
CTGGTTGTCAAGCTGGCGGAGGCAGGCCTTGGTCTATATCAAAACCAATTTTCCAGCTCCTATGAGTCACTACATGACAG
GGCTTTTGTTTGGGGAGCTGGATAGTGATTTCGACCAGATGAGTGACCTCTATTCTAGTCTAGGAATCATTCATCTCTTT
GCCCTGTCTGGTATGCAGGTTGGATTTTTCATCGATAAGTTTCGCTGGATTTTACTGCGTTTGGGCTTGACCAAGGAAGC
CGTAGATAAGTTGCAGATTCCCTTTTCAATTGTTTATGCTGGTTTGACAGGCTTTTCTGTGTCGGTGGTGCGGTCCTTGG
TCCAAAAAATTCTGGGTAATCTGGGCTTGCGGAAGCTGGATAACTTTGCGGTGACAGTTTTTGTCTGTTTCTTGTTGCTG
CCCCGATTTTTACTGACAGCAGGAGGAGTGCTGACTTTTACCTATGCTTTCTTGCTGACGGTTTTTGATTTTGAGGACTT
GGGGCAGGTCAAAAAGGCTGCGGTGGAGAGCCTCAGTATTTCGCTGGGAATTTTGCCGGTGCTGATGATCTATTTCTTTG
CCTTCCAGCCCCTGTCTATTCTCTTGACTTTTGTATTTTCCTTTGTCTTTGATGTCCTGCTCTTGCCAGGCTTGTCGGTC
ATTTTTCTCTTATCACCAATTATCAAGATTACCTGGGTCAACGGATTTTTCGTCTTGATGGAAAAAATTATTGTCTGGGT
GGCAGATTTGGGATTGCGACCTTGGATACTGGGCAAGCCGTCTGTGGTAATTCTTATTCTCTTGCTGGTCTGTCTCTTCT
TACTTTATGATTTCCACAGAAAAAAGAAATGGCTCTTAGGACTGAGCCTGGTCCTTGCTCTGCTATTTTTCATCACCAAA
CACCCGCTGGAAAACGAGGTGACGGTGGTGGACATCGGGCAGGGTGACAGCATCTTTATGCGGGATATGCGGGGGCGGAC
GGTTCTGATTGATGTGGGCGGACGAGTCGATTTCGCGGCCAAGGAAGCGTGGCAGGAGCGGTCTCGGCAGGCAAATGCAG
AGCGGACTTTGATTCCCTATCTGCATAGTCGGGGCGTGGACAGGATTGATAGTTTGGTTCTGACACACACCGACACAGAC
CATGTGGGCGATGTGCTGGAAGTGGCTAAGCAGGTCCATATTGGTCGAATTTACGTGTCGCCGGGAAGTCTGACGGTGCC
TGACTTTGTAGCAACCTTGAAAGAAATTAATGTGCCTGTCCATGTGGTCAAAGTGGGCGACCGCTTGCCGATTTTTGACT
CCTATCTGGAGGTCCTCTATCCAGACGGGACAGGCGACGGTGGCAATAATGACTCCATTGTCCTTTACGGTCGCTTGTTG
GAAACTAACTTTCTCTTTACAGGAGACCTGGAGCAAGGGGAGTTGGACTTGATAGAAACCTATCCCAACCTGCCTGTCGA
TGTCCTCAAAGCCGGTCACCACGGCTCCAAAGGTTCTTCCTATCCTGAATTTTTGGACCATATCGAAGCCAAGATTGCCT
TGATATCTGCTGGAGAAAATAACCGCTACAAGCATCCACACCAAGAAACCTTGGACCGCTTTGATAGTCGAGATATCCAA
GTCTATCGCACAGACCAGCAAGGAGCCATCCGCTTCCGAGGTTGGAAGGAGTGGAGGATTGAAACGGTGAGGAGGTAA

Domains

Predicted by InterproScan.

• Competence protein (Competence) (215-460)

• Domain of unknown function (DUF4131) (DUF4131) (30-172)

• Metallo-beta-lactamase superfamily (Lactamase_B) (493-698)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEC/celB	Streptococcus mitis SK321	54.24	99.732	0.541
comEC/celB	Streptococcus mitis NCTC 12261	53.467	100	0.538
comEC/celB	Streptococcus pneumoniae TIGR4	52.463	100	0.529
comEC/celB	Streptococcus pneumoniae Rx1	52.197	100	0.526
comEC/celB	Streptococcus pneumoniae D39	52.197	100	0.526
comEC/celB	Streptococcus pneumoniae R6	52.197	100	0.526
comEC	Lactococcus lactis subsp. cremoris KW2	49.332	100	0.495