Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   PCS90_RS13660 Genome accession   NZ_CP115386
Coordinates   2724223..2724879 (-) Length   218 a.a.
NCBI ID   WP_000611328.1    Uniprot ID   P66797
Organism   Escherichia coli strain CUVET20-PYO2     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2719223..2729879
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  PCS90_RS13630 (PCS90_13585) yecA 2720475..2721140 (-) 666 WP_000847877.1 UPF0149 family protein YecA -
  PCS90_RS13650 (PCS90_13605) pgsA 2721789..2722337 (-) 549 WP_001538881.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  PCS90_RS13655 (PCS90_13610) uvrC 2722394..2724226 (-) 1833 WP_001773939.1 excinuclease ABC subunit UvrC Machinery gene
  PCS90_RS13660 (PCS90_13615) letA 2724223..2724879 (-) 657 WP_000611328.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  PCS90_RS13665 (PCS90_13620) yecU 2725175..2725351 (+) 177 WP_001307856.1 protein YecU -
  PCS90_RS13670 (PCS90_13625) yecF 2725338..2725562 (+) 225 WP_000106474.1 DUF2594 family protein YecF -
  PCS90_RS13675 (PCS90_13630) sdiA 2725630..2726352 (-) 723 WP_001154255.1 transcriptional regulator SdiA -
  PCS90_RS13680 (PCS90_13635) tcyN 2726582..2727334 (-) 753 WP_001273000.1 L-cystine ABC transporter ATP-binding protein TcyN -
  PCS90_RS13685 (PCS90_13640) tcyL 2727331..2727999 (-) 669 WP_001158220.1 cystine ABC transporter permease -
  PCS90_RS13690 (PCS90_13645) dcyD 2728014..2729000 (-) 987 WP_001128237.1 D-cysteine desulfhydrase -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23862.63 Da        Isoelectric Point: 6.9614

>NTDB_id=704098 PCS90_RS13660 WP_000611328.1 2724223..2724879(-) (letA) [Escherichia coli strain CUVET20-PYO2]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRANAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=704098 PCS90_RS13660 WP_000611328.1 2724223..2724879(-) (letA) [Escherichia coli strain CUVET20-PYO2]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAATGGTGCCGGGCAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGAGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTTAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGATATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P66797

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

50.725

94.954

0.482
  letA Legionella pneumophila strain ERS1305867

50.725

94.954

0.482