Detailed information    

insolico Bioinformatically predicted

Overview

Name   ruvA   Type   Machinery gene
Locus tag   H7674_RS08550 Genome accession   NZ_AP023388
Coordinates   1758969..1759565 (-) Length   198 a.a.
NCBI ID   WP_011285268.1    Uniprot ID   Q48QW4
Organism   Streptococcus pyogenes strain NIH35     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1753969..1764565
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  H7674_RS08515 (SPNIH35_16330) - 1754029..1754334 (-) 306 WP_002982199.1 DUF1292 domain-containing protein -
  H7674_RS08520 (SPNIH35_16340) ruvX 1754346..1754765 (-) 420 WP_002982196.1 Holliday junction resolvase RuvX -
  H7674_RS08525 (SPNIH35_16350) - 1754762..1755031 (-) 270 WP_002982194.1 IreB family regulatory phosphoprotein -
  H7674_RS08530 (SPNIH35_16360) spx 1755145..1755543 (-) 399 WP_002982188.1 transcriptional regulator Spx -
  H7674_RS08535 (SPNIH35_16370) recA 1755834..1756970 (-) 1137 WP_011285265.1 recombinase RecA Machinery gene
  H7674_RS08540 (SPNIH35_16380) cinA 1757059..1758330 (-) 1272 WP_011285266.1 competence/damage-inducible protein A Machinery gene
  H7674_RS08545 (SPNIH35_16390) - 1758399..1758959 (-) 561 WP_011018314.1 DNA-3-methyladenine glycosylase I -
  H7674_RS08550 (SPNIH35_16400) ruvA 1758969..1759565 (-) 597 WP_011285268.1 Holliday junction branch migration protein RuvA Machinery gene
  H7674_RS08555 (SPNIH35_16410) - 1759567..1760787 (-) 1221 WP_011285269.1 MDR family MFS transporter -
  H7674_RS08560 (SPNIH35_16420) hexB 1760798..1762780 (-) 1983 WP_021340699.1 DNA mismatch repair endonuclease MutL Machinery gene
  H7674_RS08565 (SPNIH35_16430) - 1762875..1764026 (-) 1152 WP_003058754.1 tyrosine-type recombinase/integrase -
  H7674_RS09235 - 1764275..1764418 (+) 144 WP_011185066.1 putative holin-like toxin -

Sequence

Protein


Download         Length: 198 a.a.        Molecular weight: 21811.12 Da        Isoelectric Point: 6.2537

>NTDB_id=70407 H7674_RS08550 WP_011285268.1 1758969..1759565(-) (ruvA) [Streptococcus pyogenes strain NIH35]
MYDYIKGQLTKITAKYIVVETNGLGYIINVANPYSFTDSVNQLVTIYLHQVIREDAHLLFGFHTEDEKDVFLKLISVSGI
GPTTALAIVAVDDNEGLVNAIDNSDIKYLMKFPKIGKKTAQQMVLDLAGKFVEAPQETGNTKARSNKAGNTQLDEAIEAL
LALGYKAAELKKIRAFFEGTSETAEQYIKSALKLLMKG

Nucleotide


Download         Length: 597 bp        

>NTDB_id=70407 H7674_RS08550 WP_011285268.1 1758969..1759565(-) (ruvA) [Streptococcus pyogenes strain NIH35]
ATGTACGATTATATTAAAGGTCAATTGACCAAAATTACGGCAAAATACATTGTCGTTGAAACAAATGGACTAGGCTATAT
TATCAATGTAGCCAATCCTTATAGCTTTACAGATAGTGTCAACCAACTGGTAACTATTTACCTGCATCAAGTGATTCGTG
AGGATGCTCACTTGTTGTTTGGGTTTCATACGGAAGACGAAAAAGATGTTTTTCTGAAATTAATTTCTGTATCTGGCATT
GGCCCCACAACAGCTCTTGCTATTGTGGCAGTTGATGATAATGAGGGACTTGTGAATGCCATTGATAACAGTGACATTAA
GTACCTAATGAAATTTCCTAAAATTGGTAAAAAAACAGCGCAGCAAATGGTTCTTGACTTAGCTGGCAAATTTGTGGAGG
CTCCACAAGAGACTGGTAATACCAAAGCGCGCAGCAATAAAGCAGGCAATACTCAACTGGACGAAGCGATTGAAGCCCTC
CTTGCCCTCGGTTATAAGGCAGCGGAATTGAAGAAAATTCGTGCCTTCTTTGAAGGAACCTCTGAAACGGCCGAACAATA
CATCAAATCAGCCCTTAAACTATTAATGAAAGGCTAG

Domains

Predicted by InterProScan.

Helix-hairpin-helix domain (HHH_5)

(71-127)

RuvA N terminal domain (RuvA_N)

(1-61)

RuvA, C-terminal domain (RuvA_C)

(152-196)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q48QW4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ruvA Streptococcus pneumoniae TIGR4

67.005

99.495

0.667
  ruvA Streptococcus pneumoniae R6

67.005

99.495

0.667
  ruvA Streptococcus pneumoniae D39

67.005

99.495

0.667
  ruvA Bacillus subtilis subsp. subtilis str. 168

41.379

100

0.424

Multiple sequence alignment