Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   PCS82_RS05705 Genome accession   NZ_CP115376
Coordinates   1133828..1134484 (-) Length   218 a.a.
NCBI ID   WP_022645829.1    Uniprot ID   -
Organism   Escherichia coli strain CUVET20-PYO4     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1128828..1139484
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  PCS82_RS05670 (PCS82_05660) - 1129374..1130018 (-) 645 Protein_1124 transposase -
  PCS82_RS05675 (PCS82_05665) - 1130055..1130696 (+) 642 Protein_1125 hypothetical protein -
  PCS82_RS05695 (PCS82_05685) pgsA 1131394..1131942 (-) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  PCS82_RS05700 (PCS82_05690) uvrC 1131999..1133831 (-) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  PCS82_RS05705 (PCS82_05695) letA 1133828..1134484 (-) 657 WP_022645829.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  PCS82_RS05710 (PCS82_05700) yecU 1134780..1134956 (+) 177 WP_001307856.1 protein YecU -
  PCS82_RS05715 (PCS82_05705) yecF 1134943..1135167 (+) 225 WP_000106474.1 DUF2594 family protein YecF -
  PCS82_RS05720 (PCS82_05710) sdiA 1135234..1135956 (-) 723 WP_001154255.1 transcriptional regulator SdiA -
  PCS82_RS05725 (PCS82_05715) tcyN 1136186..1136938 (-) 753 WP_001272994.1 L-cystine ABC transporter ATP-binding protein TcyN -
  PCS82_RS05730 (PCS82_05720) tcyL 1136935..1137603 (-) 669 WP_001158220.1 cystine ABC transporter permease -
  PCS82_RS05735 (PCS82_05725) dcyD 1137618..1138604 (-) 987 WP_001128235.1 D-cysteine desulfhydrase -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23938.73 Da        Isoelectric Point: 6.9612

>NTDB_id=703989 PCS82_RS05705 WP_022645829.1 1133828..1134484(-) (letA) [Escherichia coli strain CUVET20-PYO4]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRANAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIAYDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=703989 PCS82_RS05705 WP_022645829.1 1133828..1134484(-) (letA) [Escherichia coli strain CUVET20-PYO4]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGGCAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACTGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATCCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTATGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

50.725

94.954

0.482
  letA Legionella pneumophila strain ERS1305867

50.725

94.954

0.482